Simultaneous paired analysis of numerical chromosomal aberrations and DNA content in osteosarcoma

Modern Pathology

Volumn 14, Issue 7, 2001, Pages 710-716

  Serra, M ^a   Tarkkanen, M ^b   Baldini, N ^a   Scotlandi, K ^a   Sarti, M ^a   Maurici, D ^a   Manara, M C ^a   Benini, S ^a   Bacchini, P ^c   Knuutila, S ^b   Picci, P ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^c Servizio di Anatomia Patologica   (Italy)

Author keywords

CGH; Cytometry; FISH; Osteosarcoma; Ploidy

Indexed keywords

DNA;

ARTICLE; CELL NUCLEUS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; CYTOFLUOROMETRY; DNA CONTENT; FLOW CYTOMETRY; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; IMAGE CYTOMETRY; METAPHASE CHROMOSOME; NUMERICAL CHROMOSOME ABERRATION; OSTEOSARCOMA; PLOIDY; PRIORITY JOURNAL; STANDARDIZATION;

BONE NEOPLASMS; CHROMOSOME ABERRATIONS; DNA, NEOPLASM; FLOW CYTOMETRY; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; OSTEOSARCOMA; PLOIDIES; TUMOR CELLS, CULTURED;

EID: 17844380243     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3880377     Document Type: Article

References (31)

1. Clinical and biological significance of aneuploidy in human tumours
2. Flow cytometry, cellular DNA content, and prognosis in human malignancy
3. Flow cytometric measurements of DNA and other cell components in human tumors: A critical appraisal
4. Cellular DNA content in human osteosarcoma: Aspects on diagnosis and prognosis
5. Flow DNA analysis of primary bone tumors. Relationship between cellular DNA content and histopathologic classification
6. Clinical importance of near-diploid tumor stem lines in patients with osteosarcoma of an extremity
7. Prognostication including DNA analysis in osteosarcoma
8. DNA cytometry of musculoskeletal tumors. A review
9. Flow cytometric studies of human osteosarcoma
10. Flow cytometric analysis of DNA in bone and soft-tissue tumors using nuclear suspensions
11. Numerical chromosome 1, 7, 9, and 11 aberrations in bladder cancer detected by in situ hybridization
12. Fluorescence in situ hybridization: Powerful molecular tool for cancer prognosis
13. Sensitive detection of chromosome copy number aberrations in prostate cancer by fluorescence in situ hybridization
14. Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors
15. Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
16. Computer image analysis of comparative genomic hybridization
17. Minimal sizes of deletions detected by comparative genomic hybridization
18. Comparative genomic hybridization in clinical cytogenetics
19. SARG: A new human osteosarcoma cell line. Expression of bone markers and of major histocompatibility antigens
20. Pre-treatment of human osteosarcoma cells with N-methylformamide enhances P-glycoprotein expression and resistance to doxorubicin
21. Absence of stimulatory effect of G-CSF on the growth of human sarcoma cells
22. Redundancy of autocrine loops in human osteosarcoma cells
23. DNA cytometry of osteosarcoma
24. Comparison of cytogenetics, interphase cytogenetics, and DNA flow cytometry in bone tumors
25. Flow cytometric DNA and cytogenetic studies in human tumors: A comparison and discussion of the differences in modal values obtained by the two methods
26. Relevance of DNA ploidy as a measure of genetic deviation: A comparison of flow cytometry and cytogenetics in 25 cases of human breast cancer
27. Gains and losses of DNA sequences in osteosarcomas by comparative genomic hybridization
28. Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas
29. DNA sequence copy number increase at 8q: A potential new prognostic marker in high-grade osteosarcoma
30. Comparative cytogenetic and DNA flow cytometric analysis of 150 bone and soft-tissue tumors
31. Tumor heterogeneity in osteosarcoma as identified by flow cytometry