Improving the estimation of change from baseline in a continuous outcome measure in the clinical trial setting

Contemporary Clinical Trials

Volumn 26, Issue 1, 2005, Pages 2-16

  Mayer Hamblett, Nicole ^a,b   Kronmal, Richard A ^b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Adaptive methods; Bias; Clinical trials; Generalized estimating equations; Nonlinear treatment response; Repeated measures

Indexed keywords

ARTICLE; CALCULATION; CLINICAL TRIAL; CYSTIC FIBROSIS; MATHEMATICAL MODEL; NONLINEAR SYSTEM; OUTCOMES RESEARCH; RANDOMIZATION; BIOASSAY; COMPUTER SIMULATION; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; FORCED EXPIRATORY VOLUME; HUMAN; RANDOMIZED CONTROLLED TRIAL; SAMPLE SIZE; STATISTICAL ANALYSIS; STATISTICAL MODEL; STATISTICS;

COMPUTER SIMULATION; CYSTIC FIBROSIS; DATA INTERPRETATION, STATISTICAL; ENDPOINT DETERMINATION; FORCED EXPIRATORY VOLUME; HUMANS; MODELS, STATISTICAL; RANDOMIZED CONTROLLED TRIALS; SAMPLE SIZE;

EID: 17844379480     PISSN: 15517144     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cct.2004.08.008     Document Type: Article

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