Immunophenotypic approach to the identification and characterization of clonal plasma cells from patients with monoclonal gammopathies

Journal of Biological Regulators and Homeostatic Agents

Volumn 18, Issue 3-4, 2004, Pages 392-398

  Perez Andres M ^a   Santiago, M ^a   Almeida, J ^a   Mateo, G ^a   Porwit MacDonald, A ^b   Bjorklund, E ^b   Valet, G ^c   Kraan, J ^d   Gratama, J W ^d   D'Hautcourt, J L ^e   Merle Beral, H ^f   Lima, M ^g   Montalban, M A ^h   San Miguel, J F ^a   Orfao, Alberto ^a  

^a Centro de Investigacion del Cancer   (Spain)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d ERASMUS MEDICAL CENTER   (Netherlands)

^e Clinique Saint Joseph at Mons   (Belgium)

^f PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^g HOSPITAL DE SANTO ANTÓNIO   (Portugal)

^h HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOD; BONE MARROW; CELL CLONE; EFFUSION; IMMUNOPHENOTYPING; LYMPH NODE; MONOCLONAL IMMUNOGLOBULINEMIA; PLASMA CELL; PLASMACYTOMA; TISSUE PRESERVATION; TONSIL; HUMAN; IMMUNOLOGY; METHODOLOGY; PARAPROTEINEMIA;

HUMANS; IMMUNOPHENOTYPING; PARAPROTEINEMIAS; PLASMA CELLS;

EID: 17844378692     PISSN: 0393974X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Orfao A, Rivas R, Lopez A, Ciudad J, Almeida J. Inmunofenotipado. In: Manual de obtención, transporte y conservación de muestras biológicas en Hematología y Hemoterapia. Ed: Josep Ma Jou. Acción Médica S.A. Madrid (Spain). 2003; pp. 83-92.
2. McCoy JP. Handling, storage, and preparation of human blood cells. In: Robinson JP, ed. Current protocols in cytometry. New York: John Wiley& Sons Inc. 1998; pp. 5.1.1-5.1.13.
3. Harada H, Kawano MM, Huang N, et al. Phenotypic difference of normal plasma cells from mature myeloma cells. Blood 1993; 81: 2658-63.
4. Terstappen LW. Identification and characterization of plasma cells in normal human bone marrow by high-resolution flow cytometry. Blood 1990; 76: 1739-47.
5. San Miguel JF. Immunophenotypic heterogeneity of multiple myeloma: Influence on the biology and clinical course of the disease. Castellano-Leones (Spain) Cooperative Group for the Study of Monoclonal Gammopathies. Br J Haematol 1991; 77: 185-90.
6. Ocqueteau M, Orfao A, Almeida J, et al. Immunophenotypic characterization of plasma cells from monoclonal gammopathy of undetermined significance patients. Implications for the differential diagnosis between MGUS and multiple myeloma. Am J Pathol 1998; 152: 1655-65.
7. Almeida J, Orfao A, Mateo G, et al. Immunophenotypic and DNA content characteristics of plasma cells in multiple myeloma and monoclonal gammopathy of undetermined significance. Pathol Biol (Paris) 1999; 47: 119-27.
8. Orfao A, Garcia-Sanz R, Lopez-Berges MC, et al. A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique. Cytometry 1994; 17: 332-9.
9. San Miguel JF, Almeida J, Mateo G, et al. Immunophenotypic evaluation of the plasma cell compartment in multiple myeloma: A tool for comparing the efficacy of different treatment strategies and predicting outcome. Blood 2002; 99: 1853-6.
10. Ishiwaka H, Tsumayama N, Mahmoud MS, et al. CD19 expression and growth inhibition of tumors in human multiple myeloma. Leukemia Lymphoma 2002; 43: 613-6.
11. Almeida J, Orfao A, Ocqueteau M, et al. High-sensitive immunophenotyping and DNA ploidy studies for the investigation of minimal residual disease in multiple myeloma. Br J Haematol 1999; 107: 121-31.
12. Perez-Andrés M, Almeida J, Martin-Ayuso M, et al. Clonal plasma cells from monoclonal gammopathy of undetermined significance, multiple myeloma and plasma cell leukemia show different expression profiles of molecules involved in the interaction with the immunological bone marrow microenvironment. Leukemia 2005; 19: 449-55.
13. Harada Y, Kawano MM, Huang N, et al. Identification of early plasma cells in peripheral blood and ther clinical significance. Br J Haematol 1996; 92: 184-91.
14. Pope B, Brown R, Gibson J, Joshua D. Plasma cells in peripheral blood stem cell harvests from patients with multiple myeloma are predominantly polyclonal. Bone Marrow Transplant 1997; 20: 205-10.
15. Mateo G, Corral M, Almeida J, et al. Immunophenotypic analysis of peripheral blood stem cell harvests from patients with multiple myeloma. Haematologica 2003; 88: 1013-21.
16. Drexler HG, Matsuo Y. Malignant hematopoietic cell lines: In vitro models for the study of multiple myeloma and plasma cell leukemia. Leuk Res 2000; 24: 681-703.
17. Jourdan M, Ferlin M, Legouffe E, et al. The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells. Br J Haematol 1998; 100: 637-46.
18. Rawstron AC, Barrans SL, Blythe D, et al. In multiple myeloma, only a single stage of neoplastic plasma cell differentiation can be identified by VLA-5 and CD45 expression. Br J Haematol 2001; 113: 794-802.
19. Kappelmayer J, Gratama JW, Karaszi E, et al. Flow cytometric detection of intracellular myeloperoxidase, CD3 and CD79a. Interaction between monoclonal antibody clones, fluorochromes and sample preparation protocols. J Immunol Methods 2000; 242: 53-65.
20. Jego G, Robillard N, Puthier D, et al. Reactive plasmacytoses are expansions of plasmablasts retaining the capacity to differentiate into plasma cells. Blood 1999; 94: 701-12.
21. Garcia-Sanz R, Orfao A, Gonzalez M, et al. Primary plasma cell leukemia: Clinical, immunophenotypic, DNA ploidy, and cytogenetic characteristics. Blood 1999; 93: 1032-7.
22. Mason D, Andre P, Bensussan A, et al. CD antigens 2002. Blood 2002; 99: 3877-80.
23. Kraan J, Gratama JW, Keeney M, D'Hautcourt JL. Setting up and calibration of a flow cytometer for multicolor immunophenotyping. J Biol Regul Homeost Agents 2003; 17: 223-33.
24. Dahl IM, Rasmussen T, Kauric G, Husebekk A. Differential expression of CD56 and CD44 in the evolution of extramedullary myeloma. Br J Haematol 2002; 116: 273-7.
25. San Miguel JF, Vidriales MB, Ocio E, et al. Immunophenotypic analysis of Waldenstrom's macroglobulinemia. Semin Oncol 2003; 30: 187-95.
26. Rawstron AC, Davies FE, DasGupta R, et al. Flow cytometric disease monitoring in multiple myeloma: The relationship between normal and neoplastic plasma cells predicts outcome after transplantation. Blood 2002; 100: 3095-100.
27. Rawstron A, Fenton J, Gonzalez D, et al. High-Risk MGUS: Identification by immunophenotype, karyotype, and clonal homogeneity. (Abstract). Blood 2003; 102: 36.