Association between microsatellite instability and clinico-pathological characteristics in sporadic colon cancer;Asociación entre la inestabilidad de microsatélites y las características clínicas y anatomopatólogicas en pacientes con cáncer de colon esporádico

Medicina Clinica

Volumn 124, Issue 12, 2005, Pages 441-446

  Guerrero, David ^a,d   Balen, Enrique ^b   Martínez Peñuela, José María ^b   García Foncillas, Jesús ^c   Larrinaga, Begoña ^b   Caballero, María Cristina ^b   Herrera, Javier ^b   Lera, José Miguel ^b  

^a Instituto de Investigación Sanitaria de Navarra   (Spain)

^b Instituto de Investigación Sanitaria de Navarra   (Spain)

^c UNIVERSITY OF NAVARRA   (Spain)

^d Ctro de Invest Biomédica   (Spain)

Author keywords

Colonic neoplasms; Disease free survival; Genes; High degree of genomic instability; Microsatellite repeats; Prognosis

Indexed keywords

FLUOROURACIL; FOLINIC ACID; IRINOTECAN; MICROSATELLITE DNA; RALTITREXED;

ARTICLE; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER STAGING; CANCER SURVIVAL; CLINICAL FEATURE; COLON CANCER; ELECTROPHORESIS; FEMALE; GENE LOCATION; GENOMIC INSTABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MICROSATELLITE MARKER; MUCINOUS CARCINOMA; POLYMERASE CHAIN REACTION; POPULATION DIFFERENTIATION; PROGNOSIS;

EID: 17844375407     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1157/13073216     Document Type: Article

References (28)

1. GLOBOCAN 2000. Cancer incidence, mortality and prevalence worldwide, Version 1.0; IARC CancerBase N.o 5.
2. Registro de Cáncer de Navarra. Sección de Enfermedades no Transmisibles y Estadísticas Vitales. Incidencia y mortalidad por cáncer en Navarra, 1993-1997. Tendencias en los últimos 25 años. Anales Sis San Navarra. 2001;24:339-62.
3. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell. 1990;61:759-67.
4. Yamamoto H, Sawai H, Perucho M. Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype. Cancer Res. 1997;57:4420-6.
5. Esteller M. Epigenetic lesions causing genetic lesions in human cancer: promoter hypermethylation of DNA repair genes. Eur J Cancer. 2000;36:2294-300.
6. Ionov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature 1993;363:558-61.
7. Chaves P, Cruz C, Lage P, Claro I, Cravo M, Leitao CN, et al. Immunohistochemical detection of mismatch repair gene proteins as a useful tool for the identification of colorectal carcinoma with the mutator phenotype. J Pathol. 2000;191:355-60.
8. Goel A, Arnold CN, Niedzwiecki D, Chang DK, Ricciardiello L, Carethers JM, et al. Characterization of sporadic colon cancer by patterns of genomic instability. Cancer Res. 2003;63:1608-14.
9. González-García I, Moreno V, Navarro M, Martí-Rague J, Marcuello E, Benasco C, et al. Standardized approach for microsatellite instability detection in colorectal carcinomas. J Natl Cancer Inst. 2000;92:544-9.
10. Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res. 1998;58:5248-57.
11. Rodriguez Bigas MA, Boland CR, Hamilton SR, Henson DE, Jass. JR, Khan PM, et al. A National Cancer Institute Workshop on Hereditary Nonpoiyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst. 1997;89:1758-62.
12. Sarma DP. The Dukes classification of colorectal cancer. JAMA. 1986;256:1447.
13. Compton CC. Colorectal carcinoma: diagnostic, prognostic and molecular features. Mod Pathol. 2003;16:376-88.
14. th ed. Philadelphia: Lippincott-Raven; 1997.
15. Graziano F, Cascinu S. Prognostic molecular markers for planning adjuvant chemotherapy trials in Dukes' B colorectal cancer patients: how much evidence is enough? Ann Oncol. 2003;14:1026-38.
16. Ikeda Y, Mori M, Akagi K, Iwashita A, Haraguchi Y, Maehara Y, et al. Differences between features of adenoma in the rectum versus sigmoid colon. Am J Gastroenterol. 2000;95:3620-3.
17. De Goede E, Filez L, Janssens J, Van Cutsem E. Follow-up of colon cancer: detection of liver metastases: benefit and periodicity. Acta Gastroenterol Belg. 1998;61:8-10.
18. Peethambaram P, Weiss M, Loprinzi CL, Novotny P, O'Fallon JR, Erlichman C, et al. An evaluation of postoperative follow-up tests in colon cancer patients treated for cure. Oncology. 1997;54:287-92.
19. Messerini L, Ciantelli M, Baglioni S, Palomba A, Zampi G, Papi L. Prognostic significance of microsatellite instability in sporadic mucinous colorectal cancers. Hum Pathol. 1999;30:629-34.
20. Biemer-Huttmann AE, Walsh MD, McGuckin MA, Simms LA, Young J, Leggett BA, et al. Mucin core protein expression in colorectal cancers with high levels of microsatellite instability indicates a novel pathway of morphogenesis. Clin Cancer Res. 2000;6:1909-16.
21. Liang JT, Chang KJ, Chen JC, Lee CC, Cheng YM, Hsu HC, et al. Clinicopathologic and carcinogenetic appraisal of DNA replication error in sporadic T3NOMO stage colorectal cancer after curative resection. Hepatogastroenterology. 1999;46:883-90.
22. Gervaz P, Cerottini JP, Bouzourene H, Hahnloser D, Doan CL, Benhattar J, et al. Comparison of microsatellite instability and chromosomal instability in predicting survival of patients with T3NO colorectal cancer. Surgery. 2002;131:190-7.
23. Gryfe R, Kim H, Hsieh ET, Aronson MD, Holowaty EJ, Bull SB, et al. Tumor microsatellite instavility and clinical outcome in young patients with colorectal cancer. N Engl J Med. 2000;342:69-77.
24. Watanabe T, Wu TT, Catalano PJ, UEKI T, Satriano R, Haller DG, et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med. 2001;344:1196-206.
25. Samowitz WS, Curtin K, Ma KN, Schaffer D, Coleman LW, Leppert M, et al. Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level. Cancer Epidemiol Biomarkers Prev. 2001;10:917-23.
26. Liang JT, Huang KC, Lai HS, Lee PH, Cheng YM, Hsu HC, et al. High-frequency microsatellite instability predicts better chemosensitivity to high-dose 5-fluorouracil plus leucovorin chemotherapy for stage IV sporadic colorectal cancer after palliative bowel resection. Int J Cancer. 2002;101:519-25.
27. Ribic CM, Sargent DJ, Moore MJ, Thibodeau SN, French AJ, Goldberg RM, et al. Tumor microsatellite-instability status as a predictor of bene-fit from Fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med. 2003;349:247-57.
28. Iacopetta B. Are there two sides to colorectal cancer? Int J Cancer. 2002;101:403-8.