Immunomonitoring of renal transplant recipients in the early posttransplant period by sequential analysis of chemokine and chemokine receptor gene expression in peripheral blood mononuclear cells

Transplantation Proceedings

Volumn 37, Issue 2, 2005, Pages 747-751

  Dalton, R S J ^a   Webber, J N ^c   Pead, P ^b   Gibbs, P J ^a   Sadek, S A ^a   Howell, W M ^b  

^a QUEEN ALEXANDRA HOSPITAL   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CHEMOKINE CCL4; CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON INDUCIBLE PROTEIN 10; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; METHYLPREDNISOLONE; RANTES; UNCLASSIFIED DRUG;

ACUTE GRAFT REJECTION; BLOOD SAMPLING; CELL SEPARATION; CONFERENCE PAPER; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; IMMUNE SYSTEM; KIDNEY BIOPSY; KIDNEY DONOR; KIDNEY GRAFT; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NEPHRECTOMY; PATIENT MONITORING; PERIPHERAL BLOOD MONONUCLEAR CELL; POSTOPERATIVE PERIOD; PREDICTION; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECIPIENT; SEQUENTIAL ANALYSIS; STATISTICAL SIGNIFICANCE; SURGICAL PATIENT; TIME;

EID: 17844371051     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2004.12.097     Document Type: Conference Paper

References (21)

1. P.J. Gibbs, S.A. Sadek, C. Cameron Immunomonitoring of renal transplant recipients in the early post transplant period by analysis of cytokine gene expression in peripheral blood mononuclear cells Transpl Proc 33 2001 3285
2. J. Pattison, P.J. Nelson, P. Huie RANTES chemokine expression in cell mediated transplant rejection of the kidney Lancet 1 1994 209
3. D.H. Adams, S.G. Hubscher, J. Fear Hepatic expression of macrophage inflammatory protein-1α and macrophage inflammatory protein-1β after liver transplantation Transplantation 61 1996 817
4. P. Cockwell, C.O. Savage Chemokines and their receptors in leukocyte trafficking and renal inflammation Nephrol Dial Transplant 12 1997 1307
5. H.-J. Grone, C. Weber, K.S. Weber Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment FASEB J 13 1999 1371
6. W. Gao, P.S. Topham, J.A. King Targeting of the chemokine receptor CCR1 suppresses development of acute and chronic cardiac allograft rejection J Clin Invest 105 2000 35
7. M. Fischereder, B. Luckow, B. Hocher CC chemokine receptor 5 and renal-transplant survival Lancet 357 2001 1758
8. L.J. Picker, E.C. Butcher Physiological and molecular mechanisms of lymphocyte homing Annu Rev Immunol 10 1992 561
9. C.R. MacKay Migration pathways and immunologic memory among T Lymphocytes Semin Immunol 4 1992 51
10. C. Agostini, F. Calabrese, F. Rea CXCR3 and its ligand CXCL10 are expressed by inflammatory cells infiltrating lung allografts and mediate chemotaxis of T cells at sites of rejection Am J Pathology 158 2001 1703
11. S. Segerer, Y. Cui, F. Eitner Expression of chemokines and chemokine receptors during human renal transplant rejection Am J Kid Diseases 37 2001 518
12. V. Grau, D. Gemsa, B. Steiniger Chemokine expression during acute rejection of rat kidneys Scand J Immunol 51 2000 435
13. L.C. Tan, W.M. Howell, J.L. Smith Sequential monitoring of peripheral T-lymphocyte cytokine gene expression in the early post renal allograft period Transplantation 71 2001 751
14. D. Rukavina, S. Balen-Marunic, G. Rubesa Perforin expression in peripheral blood lymphocytes in rejecting and tolerant kidney transplant recipients Transplantation 61 1996 285
15. S. Koga, M. Auerbach, T. Engeman T cell infiltration into Class II MHC-disparate allografts and acute rejection is dependent on the IFN-γ-induced chemokine Mig J Immunol 163 1999 4878
16. W.W. Hancock, B. Lu, W. Gao Requirement of the chemokine receptor CXCR3 for acute allograft rejection J Exp Med 192 2000 1515
17. J.A. Belperio, M.D. Burdick, M.P. Keane The role of the CC chemokine, RANTES, in acute lung allograft rejection J Immunol 165 2000 461
18. S. Qin, J.B. Rottman, P. Myers The chemokine receptors CXCR3 and CCR5 mark subsets of T cell associated with certain inflammatory reactions J Clin Invest 101 1998 746
19. S. Goddard, A. Williams, C. Morland Differential expression of chemokines and chemokine receptors shapes the inflammatory response in rejecting human liver transplants Transplantation 72 2001 1957
20. S. Segerer, M. Mack, H. Regele Expression of the CC chemokine receptor 5 in human kidney diseases Kidney Int 56 1999 52
21. R.M. Gorezynski, R.B. Adams, G.A. Levy Correlation of peripheral blood lymphocyte and intragraft cytokine mRNA expression with rejection in orthotopic liver transplantation Surgery 120 1996 496