HFRS causing hantaviruses do not induce apoptosis in confluent vero E6 and A-549 cells

Journal of Medical Virology

Volumn 76, Issue 2, 2005, Pages 234-240

  Hardestam, Jonas ^a,b   Klingström, Jonas ^a,b   Mattsson, Karin ^b   Lundkvist, Åke ^a,b  

^a SWEDISH INSTITUTE FOR INFECTIOUS DISEASE CONTROL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Dobrava; Hantaan; Puumala; Saarema; Tula hantavirus; TUNEL

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIVISION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DNA CLEAVAGE; DOBRAVA VIRUS; HANTAVIRUS; HUMAN; HUMAN CELL; IN VITRO STUDY; NICK END LABELING; NONHUMAN; PUUMALA VIRUS; SAAREMAA VIRUS; VERO CELL; VIRUS HEMORRHAGIC FEVER; VIRUS STRAIN;

ANIMALS; APOPTOSIS; CELL ADHESION; CELL LINE, TUMOR; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; DNA; HANTAVIRUS; HEMORRHAGIC FEVER WITH RENAL SYNDROME; HUMANS; IN SITU NICK-END LABELING; VERO CELLS;

EID: 17844368325     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmv.20347     Document Type: Article

References (30)

1. Avsic-Zupanc T, Xiao SY, Stojanovic A, Gligic A, van der Groen G, LeDuc JW. 1992. Characterization of Dobrava virus: A hantavirus from Slovenia, Yugoslavia. J Med Virol 38:132-137.
2. Ebihara H, Yoshimatsu K, Ogino M, Araki K, Ami Y, Kariwa H, Takashima I, Li D, Arikawa J. 2000. Pathogenicity of Hantaan virus in newborn mice: Genetic reassortant study demonstrating that a single amino acid change in glycoprotein G1 is related to virulence. J Virol 74:9245-9255.
3. Kanerva M, Mustonen J, Vaheri A. 1998. Pathogenesis of Puumala and other hantavirus infections. Rev Med Virol 8:67-86.
4. Kang JI, Park SH, Lee PW, Ahn BY. 1999. Apoptosis is induced by hantaviruses in cultured cells. Virology 264:99-105.
5. Khaiboullina SF, St Jeor SC. 2002. Hantavirus immunology. Viral Immunol 15:609-625.
6. Khaboullina SF, Rizvanov AA, Otteson E, Miyazato A, Maciejenski V, St. Jeor S. 2004. Regulation of cellular gene expression in endothelial cells by Sin Nombre and Prospect Hill viruses. Viral Immunol 17:234-251.
7. Lee JS. 1998. Clinical manifestations and treatment of HFRS and HPS. In: Lee HW, Calisher C, Schmaljohn C, editors. Manual of hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Seoul: WHO Collaborating Center for Virus Reference and Research Center (Hantavirus) Asian Institute for Life Sciences, pp 18-27.
8. Lee HW, Lee PW, Johnson KM. 1978. Isolation of the etiological agent of Korean hemorrhagic fever. J Infect Dis 137:298-308.
9. Lee HW, Lee PW, Baek LJ, Song CK, Seong IW. 1981. Intraspecific transmission of Hantaan virus, etiologic agent of Korean hemorrhagic fever, in the rodent Apodemus agrarius. Am J Trop Med Hyg 30:1106-1112.
10. Li XD, Kukkonen S, Vapalahti O, Plyusnin A, Lankinen H, Vaheri A. 2004. Tula hantavirus infection of Vero E6 cells induces apoptosis involving caspase 8 activation. J Gen Virol 85:3261-3268.
11. Lundkvist A, Plyusnin A. 2002. Molecular epidemiology of hantavirus infections. In: Leitner T, editor. Molecular epidemiology of human viruses. Boston: Kluwer Academic Publishers, pp 351-384.
12. Lundkvist Å, Fatouros A, Niklasson B. 1991. Antigenic variation of European haemorrhagic fever with renal syndrome virus strains characterized using bank vole monoclonal antibodies. J Gen Virol 72:2097-2103.
13. Lundkvist A, Hukic M, Hörling J, Gilljam M, Nichol S, Niklasson B. 1997. Puumala and Dobrava viruses cause hemorrhagic fever with renal syndrome in Bosnia-Herzegovina: Evidence of highly cross-neutralizing antibody responses in early patient sera. J Med Virol 53:51-59.
14. Markotic A, Hensley L, Geisbert T, Spik K, Schmaljohn C. 2003. Hantaviruses induce cytopathic effects and apoptosis in continuous human embryonic kidney cells. J Gen Virol 84:2197-2202.
15. McCaughey C, Shi X, Elliot RM, Wyatt DE, O'Neill HJ, Coyle PV. 1999. Low pH-induced cytopathic effect-A survey of seven hantavirus strains. J Virol Methods 81:193-197.
16. Nemirov K, Vapalahti O, Lundkvist A, Vasilenko V, Golovljova I, Plyusnina A, Niemimaa J, Henttonen H, Vaheri A, Plyusnin A. 1999. Isolation and characterization of Dobrava hantavirus carried by the striped field mouse (Apodemus agrarius) in Estonia. J Gen Virol 80:371-379.
17. Nemirov K, Lundkvist A, Vaheri A, Plyusnin A. 2003. Adaptation of Puumala hantavirus to cell culture is associated with point mutations in the coding region of the L segment and in the noncoding regions of the L segment. J Virol 77:8793-8800.
18. O'Brien V. 1998. Viruses and apoptosis. J Gen Virol 79:1833-1845.
19. Paddenberg R, Wulf S, Weber A, Heimann P, Beck LA, Mannherz HG. 1996. Internucleosomal DNA fragmentation in cultured cells under conditions reported to induce apoptosis may be caused by mycoplasma endonucleases. Eur J Cell Biol 71:105-119.
20. Pekosz A, Phillips J, Pleasure D, Merry D, Gonzalez-Scarano F. 1996. Induction of apoptosis by La Crosse virus infection and role of neuronal differentiation and human bcl-2 expression in its prevention. J Virol 70:5329-5335.
21. Pensiero MN, Sharefkin JB, Dieffenbach CW, Hay J. 1992. Hantaan virus infection of human endothelial cells. J Virol 66:5929-5936.
22. Plyusnin A. 2002. Genetics of hantaviruses: Implications to taxonomy. Arch Virol 147:665-682.
23. Pugachev KV, Frey TK. 1998. Rubella virus induces apoptosis in culture cells. Virology 250:359-370.
24. Raftery MJ, Kraus AA, Ulrich R, Krüger DH, Schönrich G. 2002. Hantavirus infection of dendritic cells. J Virol 76:10724-10733.
25. Schmaljohn C, Hjelle B. 1997. Hantaviruses: A global disease problem. Emerg Infect Dis 3:95-104.
26. Settergren B, Ahlm C, Alexeyev O, Billheden J, Stegmyr B. 1997. Pathogenetic and clinical aspects of the renal involvement in hemorrhagic fever with renal syndrome. Ren Fail 19:1-14.
27. Temonen M, Vapalahti O, Holthofer H, Brummer-Korvenkontio M, Vaheri A, Lankinen H. 1993. Susceptibility of human cells to Puumala virus infection. J Gen Virol 74:515-518.
28. Vapalahti O, Lundkvist Å, Kukkonen SK, Cheng Y, Gilljam M, Kanerva M, Manni T, Pejcoch M, Niemimaa J, Kaikusalo A, Henttonen H, Vaheri A, Plyusnin A. 1996. Isolation and characterization of Tula virus, a distinct serotype in the genus Hantavirus, family Bunyaviridae. J Gen Virol 77:3063-3067.
29. Vapalahti O, Mustonen J, Lundkvist Å, Henttonen H, Plyusnin A, Vaheri A. 2003. Hantavirus infections in Europe. Lancet Infect Dis 3:653-661.
30. Yanagihara R, Silverman DJ. 1990. Experimental infection of human vascular endothelial cells by pathogenic and nonpathogenic hantaviruses. Arch Virol 111:281-286.