Drugs from symbioses;Wirkstoffe aus symbiosen

BioSpektrum

Volumn 11, Issue 2, 2005, Pages 172-173

  Piel, Jörn ^a,b  

^a Kekule Inst F Org Chem Biochem   (Germany)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BRYOSTATIN 1; POLYKETIDE SYNTHASE;

BACTERIAL STRAIN; BIOSYNTHESIS; BUGULA NERITINA; COLEOPTERA; GENE CLUSTER; MICROFLORA; NONHUMAN; SHORT SURVEY; SYMBIOSIS;

EID: 17844361947     PISSN: 09470867     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (12)

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2. Piel, J. (2004): Metabolites from symbiotic bacteria. Nat. Prod. Rep. 21: 519-538.
3. Hentschel, U., et al. (2002): Molecular evidence for a uniform microbial community in sponges from different oceans, Appl. Environ. Microbiol. 68, 4431-4440.
4. Kellner, R. L. L and Dettner, K. (1996): Differential efficacy of toxic pederin in deterring potential arthropod predators of Paederus (Coleoptera: Staphylinidae) offspring. Oecologia 107: 293-300.
5. Norton, S. A. and Lyons, C. (2002): Blister beetles and the ten plagues. Lancet 359: 1950.
6. Kellner, R. L. L. (2001): Horizontal transmission of biosynthetic capabilities for pederin in Paederus melanurus (Coleoptera: Staphylinidae). Chemoecology 11: 127-130.
7. Piel, J. (2002): A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles. Proc. Natl. Acad. Sci. U.S.A. 99: 14002-14007.
8. Piel, J. Wen, C., Platzer, M. and Hui, D. (2004): Unprecedented diversity of catalytic domains in the first four modules of the putative pederin polyketide synthase. ChemBioChem 5: 93-98.
9. Piel, J., Höfer, I. and Hui, D. (2004): Evidence for a symbiosis island involved in horizontal acquisition of pederin biosynthetic capabilities by the bacterial symbiont of Paederus fuscipes beetles. J. Bacteriol. 186: 1280-1286.
10. Piel, J., Hui, D., Fusetani, N. and Matsunaga, S. (2004): Targeting polyketide syntheses with iteratively acting acyltransferases from metagenomes of uncultured bacterial consortia. Environ. Microbiol. 6: 921-927.
11. Piel, J., Hui, D., Wen, G. Butzke, D., Platzer, M., Fusetani, N. and Matsunaga, S. (2004): Antitumor polyketide biosynthesis by an uncultivated bacterial symbiont of the marine sponge Theonella swinhoei. Proc. Natl. Acad. Sci. U.S.A. 101: 16222-16227.
12. Hildebrand, M. et al. (2004): bryA: An unsual polyketide synthase gene from the uncultivated bacterial symbiont of the bryozoan Bugula neritina. Chem. Biol. 11: 1543-1552.