Findings and theoretical considerations on the usefulness of the acid-labile subunit in the monitoring of acromegaly

Growth Hormone and IGF Research

Volumn 11, Issue SUPPL. 1, 2001, Pages

  Morrison, Katherine M ^a   Wu, Zida ^a   Bidlingmaier, Martin ^a   Strasburger, Christian J ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Acid labile subunit; Acromegaly; Disease activity; Growth hormone; Insulin like growth factor I; Insulin like growth factor binding protein 3

Indexed keywords

BIOLOGICAL MARKER; CARRIER PROTEIN; DRUG DERIVATIVE; GLYCOPROTEIN; GROWTH HORMONE RECEPTOR; HUMAN GROWTH HORMONE; INSULIN LIKE GROWTH FACTOR BINDING PROTEIN, ACID LABILE SUBUNIT; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN, ACID LABILE SUBUNIT; PEGVISOMANT; SOMATOMEDIN BINDING PROTEIN 3;

ACROMEGALY; ANIMAL; BLOOD; DRUG ANTAGONISM; HUMAN; METABOLISM; PREDICTION AND FORECASTING; REVIEW;

ACROMEGALY; ANIMALS; BIOLOGICAL MARKERS; CARRIER PROTEINS; GLYCOPROTEINS; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; PREDICTIVE VALUE OF TESTS; RECEPTORS, SOMATOTROPIN;

EID: 17744421000     PISSN: 10966374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-6374(01)80010-1     Document Type: Review

References (5)

1. Giustina A, Barkan A, Casanueva FF, et al. Criteria for cure of acromegaly: a consensus statement. J Clin Endocrinol Metab 2000; 85: 526-529.
2. Lee CY, Wu HB, Suh DS, Rechler MM. Insulin-like growth factor-I (IGF-I) concentration in 150-kilodalton complexes containing human IGF-binding protein-3 (hIGFBP-3) after intravenous injection of adult rats with hIGFBP-3. Endocrinology 1997; 138: 1649-1657.
3. Twigg SM, Baxter RC. Insulin-like growth factor (IGF)-binding protein 5 forms an alternative ternary complex with IGFs and the acid-labile subunit. J Biol Chem 1998; 273: 6074-6079.
4. Baxter RC. Characterization of the acid-labile subunit of the growth hormone-dependent insulin-like growth factor binding protein complex. J Clin Endocrinol Metab 1988; 67: 265-272.
5. Baxter RC, Martin JL, Beniac VA. High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum. J Biol Chem 1989; 264: 11843-11848.