Characterization of Saccharomyces cerevisiae Ras1p and Chimaeric Constructs of Ras Proteins Reveals the Hypervariable Region and Farnesylation as Critical Elements in the Adenylyl Cyclase Signaling Pathway

Biochemistry

Volumn 42, Issue 50, 2003, Pages 14903-14912

  Créchet, Jean Bernard ^a   Cool, Robbert H ^b   Jacquet, Eric ^a   Lallemand, Jean Yves ^a  

^a ECOLE POLYTECHNIQUE   (France)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MEMBRANES; ENZYME INHIBITION; GENES; PROTEINS; YEAST;

NUCLEOTIDE EXCHANGE FACTORS; PROTEOLYTIC ACTIVITIES;

BIOCHEMISTRY;

ADENYLATE CYCLASE; CHIMERIC PROTEIN; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RAS PROTEIN; RAS1P PROTEIN; RAS2P PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; COMPLEX FORMATION; DNA MODIFICATION; ENZYME ACTIVATION; FARNESYLATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN HYPERVARIABLE REGION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; CELL CYCLE PROTEINS; CELL MEMBRANE; ENZYME ACTIVATION; FUNGAL PROTEINS; GENES, RAS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; ONCOGENE PROTEIN P21(RAS); PROTEIN BINDING; PROTEIN ISOPRENYLATION; PROTEIN STRUCTURE, TERTIARY; RAS GTPASE-ACTIVATING PROTEINS; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; RAS-GRF1; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SIGNAL TRANSDUCTION; VARIATION (GENETICS);

CHIMAERIFORMES; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 17744407706     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0349928     Document Type: Article

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