Effects of single and repeated administration of sulthiame on amygdaloid kindled seizures in rats

Epilepsy Research

Volumn 27, Issue 2, 1997, Pages 81-87

  Song, Hong Ki ^b   Hamada, Koichi ^a   Yagi, Kazuichi ^a   Seino, Masakazu ^a  

^a SHIZUOKA INSTITUTE OF EPILEPSY AND NEUROLOGICAL DISORDERS   (Japan)

^b Kangdong Sacred Heart Hospital   (South Korea)

Author keywords

Kindling; Rats; Sulthiame; Therapeutic effect

Indexed keywords

MACROGOL; SULTIAME;

AFTERDISCHARGE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CLONUS; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; GRAND MAL SEIZURE; INTRAPERITONEAL DRUG ADMINISTRATION; KINDLING; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE THRESHOLD;

AMYGDALA; ANIMALS; ANTICONVULSANTS; ELECTROENCEPHALOGRAPHY; KINDLING, NEUROLOGIC; MALE; MYOCLONUS; RATS; RATS, WISTAR; SEIZURES; THIAZINES;

EID: 17744401821     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0920-1211(96)01012-1     Document Type: Article

References (21)

1. Albe-Fessard, D., Stutinsky, F. and Libouban, S., Atlas stereotaxique du diencephale du rat blanc, CNRS, Paris, 1966.
2. Albertson, T.E., Peterson, S.L. and Stark, L.G., Anticonvulsant drugs and their antagonism of kindled amydaloid seizures in rats, Neuropharmacology, 19 (1980) 643-652.
3. Albertson, T.E., Joy, R.M. and Stark, L.G., Carbamazepine: A pharmacological study in the kindling model of epilepsy, Neuropharmacology, 23 (1984) 1117-1123.
4. Ashton, D. and Wauquier, A., Behavioral analysis of the effects of 15 anticonvulsants in the amygdaloid kindled rat, Psychopharmacology, 65 (1979) 7-13.
5. Berry, D.J., Clarke, L.A. and Vallins, G.E., Determination of sulthiame, tetrahydro-2-p-sulphamoyl-phenyl-2H-1,2-thiazine-1,1-dioxide, in plasma at therapeutic concentrations, using high performance liquid chromatography, J. Chromatogr., 171 (1979) 363-370.
6. Doose, H., Baier, W.K., Ernst, J.P., Tuxhorn, I. and Völzke, E., Benign partial epilesy-Treatment with sulthiame, Dev. Med. Child. Neurol., 30 (1988) 683-684.
7. Eadie, M.J. and Tyrer, J.H. (Eds.), Anticonvulsant therapy: Pharmacological Basis and Practice, Churchill Livingstone, London, 1989, pp. 291-294.
8. Green, J.R., Troupin, A.S., Halpern, L.M., Friel, P. and Kanarek, P., Sulthiame: Evaluation as an anticonvulsant, Epilepsia, 15 (1974) 329-349.
9. Hamada, K., Ishida, S., Yagi, K. and Seino, M., Effects of zonisamide and acetazolamide on amygdaloid-kindled seizure in rats: Repeated administration, Epilepsia, 36 (Suppl.3) (1995) 39.
10. Hamada, K., Song, H.K., Ishida, S., Yagi, K. and Seino, M., Therapeutic effects of zonisamide and some conventional antiepileptic drugs on amygdaloid kindling in rats, J. Brain Science, 22 (1996) 7-15.
11. Ishida, S., Sagisaka, M., Higashi, T., Yagi, K. and Seino, M., Effects of antiepileptic drugs on limbic kindling in adults rats with repeated electroconvulsive shocks during infantile period-A preliminary report about effect of sodium valproate, Ann. Rep. Pharmacopsychiat. Res. Found., 15 (1984) 92-97 (English abstract).
12. Jibiki, I., Urata, K., Matsuda, H., Furuta, H., Yamaguchi, N. and Hisada, K., Efficacy of sulthiame (Ospolot®) on motor partial seizure status during sleep in a patient with motor cortrx epilepsy, Acta. Neurol., 49 (1993) 25-32.
13. Lister, R.G., LeDuc, B.W., Greenblatt, D.J. and File, S.E., Poor bioavailability of CGS 8216 in a water/Tween vehicle following intraperitoneal injection, Psychopharmacology, 91 (1987) 260-261.
14. Löscher, W., Nolting, B. and Fassbender, C.P., The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. I. The influence of administration vehicles, Epilepsy Res., 7 (1990) 173-181.
15. Löscher, W. and Schmidt, D., Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations, Epilepsy Res., 2 (1988) 145-181.
16. Lothman, E.W., Williamson, J.M. and VanLandingham K.E., Intraperitoneal phenytoin suppresses kindled responses: Effects on motor and electrographic eizures, Epilepsy Res., 9 (1991) 11-18.
17. Racine, RJ., Modification of seizure activity by electrical stimulation: II. Motor seizure, Electroenceph. Clin. Neurophysiol., 32 (1972) 281-294.
18. Silver, J.M., Shin, C. and McNamara, J.O., Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilepsy, Ann. Neurol., 29 (1991) 356-363.
19. Smyth, V.O.G., The use of Ospolot in temporal lobe epielpsy, Epilepsia, 5 (1964) 293-295.
20. Uthman, B.M. and Wilder, B.J., Less commonly used antiepileptic drugs. In: E. Wyllie (Ed.), The treatment of epilepsy: Principles and Practice, Lee and Febiger, Philadelphia, 1993, pp. 959-973.
21. Wada, J.A., Pharmacological prophylaxis in the kindling model of epilepsy, Arch. Neurol., 34 (1977) 389-395.