Long-term production of erythropoietin after electroporation-mediated transfer of plasmid DNA into the muscles of normal and uremic rats

Gene Therapy

Volumn 8, Issue 6, 2001, Pages 461-468

  Maruyama, H ^a   Ataka, K ^a   Gejyo, F ^a   Higuchi, N ^a   Ito, Y ^a   Hirahara, H ^a   Imazeki, I ^b   Hirata, M ^b   Ichikawa, F ^b   Neichi, T ^b   Kikuchi, H ^a   Sugawa, M ^b   Miyazaki, J ^c  

^a NIIGATA UNIVERSITY   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Chronic renal failure; Electroporation; Erythropoietin; Gene therapy; Hypertension

Indexed keywords

ERYTHROPOIETIN; PLASMID DNA; RECOMBINANT ERYTHROPOIETIN;

ANEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG DELIVERY SYSTEM; ELECTROPORATION; ERYTHROPOIESIS; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; HYPERTENSION; IN VIVO STUDY; MALE; MUSCLE; NEPHRECTOMY; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL; RAT; TARGET ORGAN; THROMBOCYTE COUNT; UREMIA;

ANIMALS; DNA; ELECTROPORATION; ERYTHROCYTES; ERYTHROPOIETIN; GENE THERAPY; HYPERTENSION, RENAL; KIDNEY FAILURE, CHRONIC; LINEAR MODELS; MODELS, ANIMAL; MUSCLE, SKELETAL; RATS; UREMIA;

ANIMALIA;

EID: 17744391278     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301412     Document Type: Article

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