An activity-dependent switch from facilitation to inhibition in the control of excitotoxicity by group I metabotropic glutamate receptors

European Journal of Neuroscience

Volumn 13, Issue 8, 2001, Pages 1469-1478

  Bruno, Valeria ^a   Battaglia, Giuseppe ^a   Copani, Agata ^b   Cespédes, Virtudes M ^c   Galindo, María F ^c   Ceña, Valentín ^c   Sánchez Prieto, Jose ^d   Gasparini, Fabrizio ^e   Kuhn, Rainer ^e   Flor, Peter J ^e   Nicoletti, Ferdinando ^a,b  

^a IRCCS NEUROMED   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c INSTITUTO DE NEUROCIENCIAS   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Activity dependent switch; Cortical cultures; Excitotoxicity; Group I metabotropic glutamate receptors; Hippocampal cultures; NMDA

Indexed keywords

1 (5 ISOQUINOLINESULFONYL) 2 METHYLPIPERAZINE; 3,5 DIHYDROXYPHENYLGLYCINE; CALPHOSTIN C; GLUTAMATE RECEPTOR AGONIST; METABOTROPIC RECEPTOR; PERTUSSIS TOXIN; PROTEIN KINASE C; QUISQUALIC ACID;

AMINO ACID BRAIN LEVEL; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DRUG POTENCY; FACILITATION; FETUS; MOUSE; NERVE DEGENERATION; NERVE EXCITABILITY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PYRAMIDAL NERVE CELL; RAT; RECEPTOR UPREGULATION; REGULATORY MECHANISM; SYNAPTIC TRANSMISSION;

ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; ENZYME ACTIVATION; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; MICE; N-METHYLASPARTATE; NERVE DEGENERATION; NEURAL INHIBITION; NEUROPROTECTIVE AGENTS; NEUROTOXINS; PROTEIN KINASE C; QUISQUALIC ACID; RECEPTORS, METABOTROPIC GLUTAMATE; RESORCINOLS; TIME FACTORS;

EID: 17744379361     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0953-816x.2001.01541.x     Document Type: Article

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