The clinical expression of hemochromatosis in Oslo, Norway: Excessive oral iron intake may lead to secondary hemochromatosis even in HFE C282Y mutation negative subjects

Scandinavian Journal of Gastroenterology

Volumn 35, Issue 12, 2000, Pages 1301-1307

  Bell, H ^a   Berg, J P ^a   Undlien, D E ^a   Distante, S ^a   Raknerud, N ^a   Heier, H E ^a   Try, K ^a   Thomassen, Y ^a   Haug, E ^a   Raha Chowdhury, R ^a   Thorsby, E ^a  

^a AKER UNIVERSITY HOSPITAL   (Norway)

Author keywords

Arthralgia; Blood donors; Clinical expression; Hemochromatosis; HFE gene mutation; Iron supplementation

Indexed keywords

FERRITIN; IRON; TRANSFERRIN;

ADULT; AGED; ARTHROPATHY; ARTICLE; ASTHENIA; BLOOD BANK; CLINICAL FEATURE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE SEVERITY; FATIGUE; FEMALE; FERRITIN BLOOD LEVEL; GENE MUTATION; GENOTYPE; HEMOCHROMATOSIS; HOMOZYGOSITY; HUMAN; HUMAN CELL; IRON INTAKE; IRON STORAGE; IRON THERAPY; LIVER BIOPSY; LIVER CELL; MAJOR CLINICAL STUDY; MALE; NORWAY; PERCUTANEOUS BIOPSY; PREVALENCE; PRIORITY JOURNAL; TRANSFERRIN BLOOD LEVEL;

ADULT; AGED; CYTOCHROMES; FEMALE; GENOTYPE; HEMOCHROMATOSIS; HUMANS; MALE; MIDDLE AGED; MUTATION; NORWAY; POLYMERASE CHAIN REACTION; PREVALENCE;

EID: 17744371115     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/003655200453665     Document Type: Article

References (27)

1. Prevalence of hemochromatosis among first-time and repeat blood donors in Norway
2. Long-term survival in patients with hereditary hemochromatosis
3. A novel MCH class I-like gene is mutated in patients with hereditary hemochromatosis
4. High prevalence of the hemochromatosis associated HFE gene mutation in a healthy Norwegian population in the city of Oslo and its phenotypic expression
5. Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis
6. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
7. Polymorphism in intron 4 of HFE gene may cause overestimation of C282Y homozygote prevalence in haemochromatosis
8. Liver fibrosis in genetic hemochromatosis. Respective roles of iron and non-iron-related factors in 127 homozygous patients
9. The relationship between iron overload, clinical symptoms and age in 410 patients with genetic hemochromatosis
10. Hemochromatosis and other iron storage disorders
11. Molecular medicine and hemochromatosis: At the crossroads
12. A genotypic study of 207 unrelated probands diagnosed as "genetic hemochromatosis" on "classical" phenotypic criteria
13. HFE mutations in patients with hereditary haemochromatosis in Sweden
14. Expression of HLA-linked hemochromatosis in subjects homozygous or heterozygous for the C282Y mutation
15. A population-based study of the clinical expression of the hemochromatosis gene
16. HFE gene mutation (C282Y) and phenotypic expression among a hospitalised population in a high prevalence area of hemochromatosis
17. Haemochromatosis and HLA-H
18. A simple genetic test identifies 90% of UK patients with haemochromatosis
19. Hemochromatosis and HLA-H
20. Clinical and family studies in genetic hemochromatosis: Microsatellite and HFE studies in five atypical families
21. Mutations in the MCH class I-like candidate gene for hemochromatosis in French patients
22. Mutation analysis of the HLA-H gene in Italian hemochromatosis patients
23. Genetic and clinical description of hemochromatosis probands and heterozygotes: Evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis
24. Predominance of the HLA-H Cys282Tyr mutation in Austrian patients with genetic haemochromatosis
25. Hereditary hemochromatosis. Gene discovery and its implications for population-based screening
26. Haemochromatosis and exercise related joint pains
27. Arthritis in hemochromatosis