Granulation of acetaminophen by a rotating fluidized-bed granulator

Pharmaceutical Development and Technology

Volumn 5, Issue 2, 2000, Pages 141-151

  Kawaguchi, Takeshi ^a   Sunada, Hisakazu ^a   Yonezawa, Yorinobu ^a   Danjo, Kazumi ^a   Hasegawa, Masaki ^b   Makino, Tadashi ^c   Sakamoto, Hiroshi ^d   Fujita, Kanji ^e   Tanino, Tadatsugu ^f   Kokubo, Hiroyasu ^g  

^a MEIJO UNIVERSITY   (Japan)

^b ASAHI CHEMICAL INDUSTRY CO   (Japan)

^c TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

^d Powder Tech Engineering Laboratory   (Japan)

^e Kikusui Seisakusho Co Ltd   (Japan)

^f SHIONOGI AND CO LTD   (Japan)

^g SHIN ETSU CHEMICAL CO LTD   (Japan)

Author keywords

Acetaminophen; Ascorbic acid; Ethenzamide; Granulation; Granule hardness; Rotating fluidized bed granulator; Standard formulation; Tableting

Indexed keywords

ASCORBIC ACID; ETHENZAMIDE; HYDROXYPROPYLCELLULOSE; LACTOSE; MAGNESIUM STEARATE; PARACETAMOL; STARCH;

ARTICLE; DRUG GRANULATION; FLUIDIZED BED; PLASTICITY; PRIORITY JOURNAL; TABLET COMPRESSION; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET HARDNESS; WETTABILITY;

ACETAMINOPHEN; ANALGESICS, NON-NARCOTIC; ASCORBIC ACID; CHEMISTRY, PHARMACEUTICAL; DRUG COMPOUNDING; HARDNESS; PARTICLE SIZE; POROSITY; POWDERS; SALICYLAMIDES; SOLUBILITY; TABLETS; TENSILE STRENGTH;

EID: 17644446483     PISSN: 10837450     EISSN: None     Source Type: Journal    
DOI: 10.1081/PDT-100100529     Document Type: Article

References (9)

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