Use of various microdosimetric models for the prediction of radon induced damage in human lungs

Radiation Protection Dosimetry

Volumn 104, Issue 2, 2003, Pages 127-137

  Bohm R ^a   Nikodemova D ^b   Holy K ^a  

^a Physics and Informatics   (Slovakia)

^b INST OF PREV AND CLINICAL MEDICINE   (Slovakia)

Author keywords

[No Author keywords available]

Indexed keywords

RADON; URANIUM;

ALPHA RHYTHM; ARTICLE; CELL TRANSFORMATION; CIGARETTE SMOKING; COMPARTMENT MODEL; CONTROLLED STUDY; CZECHOSLOVAKIA; HUMAN; HUMAN CELL; LUNG ALVEOLUS CELL; LUNG INJURY; LUNG PARENCHYMA; MATHEMATICAL COMPUTING; MICRODOSIMETRY; MUCUS; PERFORMANCE; PREDICTION; RADIATION ENERGY; RADIATION EXPOSURE; RADIATION HAZARD; RADIATION INJURY; RADIOLOGICAL PARAMETERS; RELIABILITY; RISK ASSESSMENT; TARGET CELL; THICKNESS; URANIUM MINE;

EID: 17644437383     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.rpd.a006173     Document Type: Article

References (23)

1. ICRP. Human respiratory tract model for radiological protection. ICRP 66 (Oxford: Pergamon) (1994).
2. National Research Council (NRC). Comparative dosimetry radon in mines and homes. (Washington, DC: NRC) (1991).
3. Tomášek, L., Darby, S. C., Fearn, T., Swerdlow, A. J., Placek, V. and Kunz, E. Patterns of lung cancer mortality among uranium miners in West Bohemia with varying rates of exposure to radon and its progeny. Radiat. Res. 137, 2511-2261 (1994).
4. Birchall, A. and James, A.C. Uncertainty analysis of the effective dose per unit exposure from radon progeny and implications for ICRP risk-weighting factors. Radiat. Prot. Dosim. 53(1-4), 133-140 (1994).
5. Harley, N. H. Interaction of α particles with bronchial cells. Health Phys. 55(4), 665-669 (1988).
6. Marsch, J. W. and Birchall, A. Determination of lung-to-blood absorption rates for lead and bismuth that are appropriate for radon progeny. Radiat. Prot. Dosim. 83(4), 331-337 (1999).
7. Brenner, D. J., Miller, R. C., Huang, Y. and Hall, E. J. The biological effectiveness of radon-progeny alpha particles. III. Quality factors. Radiat. Res. 142(1), 61-69 (1995).
8. Harley, N. H. and Pasternack., B. S. Alpha absorption measurements applied to lung dose from radon daughters. Health Phys. 23(6), 771-782 (1972).
9. Kraft, G., Krämer, M. and Scholz, M. LET, track structure and models. Radiat. Environ. Biophys. 31, 161-180 (1992).
10. Rossi, H. H. Geometric domains in cellular radiobiology. Radiat. Prot. Dosim. 52(1-4), 9-12 (1994).
11. Rossi, H. H. and Kellerer, A. M. Radiation carcinogenesis at low doses. Science 175, 200-204 (1972).
12. Hofmann, W. and Heistracher, T. Track structure predictions of radon-induced biological effects in human bronchial epithelium. Environ. Int. 22(1), 949-957 (1996).
13. Katz, R. and Hofmann, W. Biological effects of low doses of ionizing radiations: particle tracks in radiobiology. Nucl. Instrum. Methods 203, 433-442 (1982).
14. Katz, R., Zachariah, R., Cucinitta, F. A. and Zhang, Ch. Survey of cellular radiosensitivity parameters. Radiat. Res. 140, 356-365 (1994).
15. Sedlák, A. Microdosimetric approach to the problem of lung cancer induced by radon progeny. Health Phys. 70(5), 680-688 (1996).
16. Crawford-Brown, D. J. and Hofman W. Extension of a general state-vector model of radiation carcinogenesis to consideration of dose rate. Math. Bios. 115, 123-144 (1993).
17. Miller, R. C., Richards, M., Brenner, D. J., Hall, E. J., Jostes, R., Hui, T. E. and Brooks, A. L. Comparison of oncogenic transformation by accelerator-produced monoenergetic alpha particles and by polyenergetic alpha particles from radon progeny. Radiat. Res. 146(1), 75-80 (1996).
18. Miller, R. C., Marino, A., Brenner, D. J. and Martin, S. G. The biological effectiveness of radon-progeny alpha particles. II. Oncogenic transformation as a function of linear energy transfer. Radiat. Res. 142(1), 54-60 (1995).
19. Hieber, L., Ponsel, G., Roos, H., Fen, S., Fromke, E. and Kellerer, A. M. Absence of a dose-rate effect in the transformation of C3H 10T1/2 cells by alpha particles. Int. J. Radiat. Biol. 52, 859-869 (1987).
20. Mercer, R., Russel, M. L. and Crapo, J. D. Radon dosimetry based on the depth distribution of nuclei in human and rat lung. Health Phys. 61(1), 117-131 (1991).
21. National Research Council, Committee on Health Risks of Exposure to Radon. Health effects of exposure to radon (BEIR VI) (Washington, DC: National Academy Press) (1999).
22. Monchaux, G., Morlier, J. P., Altmeyer, S., Debroche, M. and Morin, M. Influence of exposure rate on lung cancer induction in rats exposed to radon progeny. Radiat. Res. 152(6), S137-140 (1999).
23. Mitchel, R. E. J., Jackson, J. S. and Heinmiller, B. Inhaled uranium ore dust and lung cancer risk in rats. Health Phys. 76(2), 145-155 (1999).