Comparative bioavailability/bioequivalence of two different sertraline formulations: A randomised, 2-period × 2-sequence, crossover clinical trial in healthy volunteers

Arzneimittel-Forschung/Drug Research

Volumn 55, Issue 4, 2005, Pages 191-197

  Almeida, Susana ^a,d   Portolés, Antonio ^b   Terleira, Ana ^b   Filipe, Augusto ^a   Cea, Eva ^b   Caturla, Maria Cruz ^c  

^a Tecnimede Group   (Portugal)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c Anapharm Europe   (Spain)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Antidepressant; CAS 79617 96 2; Sertraline, bioavailability, bioequivalence, pharmacokinetics, sex related analysis

Indexed keywords

SEROTONIN UPTAKE INHIBITOR; SERTRALINE;

ABDOMINAL DISCOMFORT; ADULT; ANALYSIS OF VARIANCE; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIARRHEA; DISTRIBUTION VOLUME; DIZZINESS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; FEMALE; HEADACHE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INSOMNIA; LINEAR REGRESSION ANALYSIS; MALE; NAUSEA; NORMAL HUMAN; PLASMA; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; TABLET FORMULATION; TANDEM MASS SPECTROMETRY; TREMOR; VOMITING;

EID: 17644421772     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1296844     Document Type: Article

References (10)

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