메뉴 건너뛰기




Volumn 7, Issue 5-6, 2005, Pages 694-700

Antioxidants as therapy for Parkinson's disease

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 8 HYDROXY 2 DEOXYGUANOSINE; 8 HYDROXYGUANINE; ADENOSINE TRIPHOSPHATE; ALPHA TOCOPHEROL; ANTIOXIDANT; CLIOQUINOL; DEOXYGUANOSINE DERIVATIVE; DOPAMINE RECEPTOR STIMULATING AGENT; EPIGALLOCATECHIN GALLATE; GREEN TEA EXTRACT; IRON CHELATE; LEVODOPA; MELATONIN; NITRIC OXIDE; NITRONE; OXIDOPAMINE; PEROXYNITRITE; POLYPHENOL; PRAMIPEXOLE; REACTIVE OXYGEN METABOLITE; ROPINIROLE; SELEGILINE; SUPEROXIDE DISMUTASE; UBIQUINONE; UNCLASSIFIED DRUG;

EID: 17644421395     PISSN: 15230864     EISSN: None     Source Type: Journal    
DOI: 10.1089/ars.2005.7.694     Document Type: Review
Times cited : (7)

References (75)
  • 1
    • 0030805622 scopus 로고    scopus 로고
    • A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • Alam ZI, Daniel SE, Lees AJ, Marsden DC, Jenner P, and Halliwell B. A generalized increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem 69: 1326-1329, 1997.
    • (1997) J Neurochem , vol.69 , pp. 1326-1329
    • Alam, Z.I.1    Daniel, S.E.2    Lees, A.J.3    Marsden, D.C.4    Jenner, P.5    Halliwell, B.6
  • 2
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine levels in substantia nigra
    • Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P, and Halliwell B. Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels in substantia nigra. J Neurochem 69: 1196-2003, 1997.
    • (1997) J Neurochem , vol.69 , pp. 1196-2003
    • Alam, Z.I.1    Jenner, A.2    Daniel, S.E.3    Lees, A.J.4    Cairns, N.5    Marsden, C.D.6    Jenner, P.7    Halliwell, B.8
  • 3
    • 0035968070 scopus 로고    scopus 로고
    • Neuroprotective effects of pramipexole in young and aged MPTP-treated mice
    • Anderson DW, Neavin T, Smith JA, and Schneider JS. Neuroprotective effects of pramipexole in young and aged MPTP-treated mice. Brain Res 905: 44-53, 2001.
    • (2001) Brain Res , vol.905 , pp. 44-53
    • Anderson, D.W.1    Neavin, T.2    Smith, J.A.3    Schneider, J.S.4
  • 5
    • 0031594295 scopus 로고    scopus 로고
    • 10 attenuates the 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice
    • 10 attenuates the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice. Brain Res 783: 109-114, 1998.
    • (1998) Brain Res , vol.783 , pp. 109-114
    • Beal, M.F.1    Matthews, R.T.2    Tieleman, A.3    Shults, C.W.4
  • 6
    • 0032712884 scopus 로고    scopus 로고
    • Diagnostic and therapeutic applications of azulenyl nitrone spin traps
    • Becker DA. Diagnostic and therapeutic applications of azulenyl nitrone spin traps. Cell Mol Life 56: 626-633, 1999.
    • (1999) Cell Mol Life , vol.56 , pp. 626-633
    • Becker, D.A.1
  • 7
    • 0028641246 scopus 로고
    • Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury
    • Beckman JS. Peroxynitrite versus hydroxyl radical: the role of nitric oxide in superoxide-dependent cerebral injury. Ann N Y Acad Sci 738: 69-75, 1994.
    • (1994) Ann N Y Acad Sci , vol.738 , pp. 69-75
    • Beckman, J.S.1
  • 8
    • 0031721802 scopus 로고    scopus 로고
    • Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
    • Bravo L. Polyphenols: chemistry, dietary sources, metabolism, and nutritional significance. Nutr Rev 56: 317-333, 1998.
    • (1998) Nutr Rev , vol.56 , pp. 317-333
    • Bravo, L.1
  • 10
    • 0024500857 scopus 로고
    • Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: Behavioral and biochemical evidence
    • Cadet JL, Katz M, Jackson-Lewis V, and Fahn S. Vitamin E attenuates the toxic effects of intrastriatal injection of 6-hydroxydopamine (6-OHDA) in rats: behavioral and biochemical evidence. Brain Res 476: 10-15, 1989.
    • (1989) Brain Res , vol.476 , pp. 10-15
    • Cadet, J.L.1    Katz, M.2    Jackson-Lewis, V.3    Fahn, S.4
  • 11
    • 0031842356 scopus 로고    scopus 로고
    • Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion
    • Cassarino DS, Fall CP, Smith TS, and Bennett JP Jr. Pramipexole reduces reactive oxygen species production in vivo and in vitro and inhibits the mitochondrial permeability transition produced by the parkinsonian neurotoxin methylpyridinium ion. J Neurochem 71: 295-301, 1998.
    • (1998) J Neurochem , vol.71 , pp. 295-301
    • Cassarino, D.S.1    Fall, C.P.2    Smith, T.S.3    Bennett Jr., J.P.4
  • 13
    • 0036746177 scopus 로고    scopus 로고
    • Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate
    • Choi JY, Park CS, Kim DJ, Cho MH, Jin BK, Pie JE, and Chung WG. Prevention of nitric oxide-mediated 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced Parkinson's disease in mice by tea phenolic epigallocatechin 3-gallate. Neurotoxicology 23: 367-374, 2002.
    • (2002) Neurotoxicology , vol.23 , pp. 367-374
    • Choi, J.Y.1    Park, C.S.2    Kim, D.J.3    Cho, M.H.4    Jin, B.K.5    Pie, J.E.6    Chung, W.G.7
  • 14
    • 0021712735 scopus 로고
    • Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP) in monkeys
    • Cohen G, Pasik P, Cohen B, Leist A, Mytilineou C, and Yahr MD. Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) in monkeys. Eur J Pharmacol 106: 209-210, 1984.
    • (1984) Eur J Pharmacol , vol.106 , pp. 209-210
    • Cohen, G.1    Pasik, P.2    Cohen, B.3    Leist, A.4    Mytilineou, C.5    Yahr, M.D.6
  • 15
    • 0035170284 scopus 로고    scopus 로고
    • Melatonin protects against 6-OHDA-induced neurotoxicity in rats: A role for mitochondrial complex 1 activity
    • Dabbeni-Sala F, Di Santo S, Franceschini D, Skaper SD, and Giusti P. Melatonin protects against 6-OHDA-induced neurotoxicity in rats: a role for mitochondrial complex 1 activity. FASEB J 15: 164-170 2001.
    • (2001) FASEB J , vol.15 , pp. 164-170
    • Dabbeni-Sala, F.1    Di Santo, S.2    Franceschini, D.3    Skaper, S.D.4    Giusti, P.5
  • 19
    • 0025821265 scopus 로고
    • Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia
    • Dexter DT, Carayon A, Javoy-Agid F, Agid Y, Wells FR, Daniel SE, Lees AJ, Jenner P, and Marsden CD. Alterations in the levels of iron, ferritin and other trace metals in Parkinson's disease and other neurodegenerative diseases affecting the basal ganglia. Brain 114(Pt 4): 1953-1975, 1991.
    • (1991) Brain , vol.114 , Issue.PART 4 , pp. 1953-1975
    • Dexter, D.T.1    Carayon, A.2    Javoy-Agid, F.3    Agid, Y.4    Wells, F.R.5    Daniel, S.E.6    Lees, A.J.7    Jenner, P.8    Marsden, C.D.9
  • 21
    • 0028287193 scopus 로고
    • Erratum
    • Dexter DT, Holley AE, Flitter WD, Slater TF, Wells FR, Daniel SE, Lees AJ, Jenner P, and Marsden CD. Increased levels of lipid hydroperoxides in the parkinsonian substantia nigra: an HPLC and ESR study. Mov Disord 9: 92-97, 1994. Erratum in: Mov Disord 9: 380, 1994.
    • (1994) Mov Disord , vol.9 , pp. 380
  • 22
    • 0026636491 scopus 로고
    • A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease
    • Fahn S. A pilot trial of high-dose alpha-tocopherol and ascorbate in early Parkinson's disease. Ann Neurol 32 Suppl: S128-S132, 1992.
    • (1992) Ann Neurol , vol.32 , Issue.SUPPL.
    • Fahn, S.1
  • 24
    • 0023724071 scopus 로고
    • Case-control study of early life dietary factors in Parkinson's disease
    • Golbe LI, Farrell TM, and Davis PH. Case-control study of early life dietary factors in Parkinson's disease. Arch Neurol 45: 1350-1353, 1988.
    • (1988) Arch Neurol , vol.45 , pp. 1350-1353
    • Golbe, L.I.1    Farrell, T.M.2    Davis, P.H.3
  • 25
    • 0033761653 scopus 로고    scopus 로고
    • Chemical and pharmacological aspects of heteroaryl-nitrones
    • Goldstein S and Lestage P. Chemical and pharmacological aspects of heteroaryl-nitrones. Curr Med Chem 7: 1255-1267, 2000.
    • (2000) Curr Med Chem , vol.7 , pp. 1255-1267
    • Goldstein, S.1    Lestage, P.2
  • 26
    • 0032589184 scopus 로고    scopus 로고
    • Potent neuroprotective and antioxidant activity of apomorphine in MPTP and 6-hydroxydopamine induced neurotoxicity
    • Grünblatt E, Mandel S, Gassen M, and Youdim MB. Potent neuroprotective and antioxidant activity of apomorphine in MPTP and 6-hydroxydopamine induced neurotoxicity. J Neural Transm Suppl 55: 57-70, 1999.
    • (1999) J Neural Transm Suppl , vol.55 , pp. 57-70
    • Grünblatt, E.1    Mandel, S.2    Gassen, M.3    Youdim, M.B.4
  • 27
    • 0034796353 scopus 로고    scopus 로고
    • Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
    • Halliwell B. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18: 685-716, 2001.
    • (2001) Drugs Aging , vol.18 , pp. 685-716
    • Halliwell, B.1
  • 28
    • 0037105296 scopus 로고    scopus 로고
    • Structure and function of xanthine oxidoreductase: Where are we now?
    • Harrison R. Structure and function of xanthine oxidoreductase: where are we now? Free Radic Biol Med 33: 774-797, 2002.
    • (2002) Free Radic Biol Med , vol.33 , pp. 774-797
    • Harrison, R.1
  • 29
    • 0021893798 scopus 로고
    • Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6- tetrahydropyridine (MPTP) in the mouse: Relationships between monoamine oxidase, MPTP metabolism and neurotoxicity
    • Heikkila RE, Hess A, and Duvoisin RC. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) in the mouse: relationships between monoamine oxidase, MPTP metabolism and neurotoxicity. Life Sci 36: 231-236, 1985.
    • (1985) Life Sci , vol.36 , pp. 231-236
    • Heikkila, R.E.1    Hess, A.2    Duvoisin, R.C.3
  • 31
    • 0033554203 scopus 로고    scopus 로고
    • Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist
    • Iida M, Miyazaki I, Tanaka K, Kabuto H, Iwata-Ichikawa E, and Ogawa N. Dopamine D2 receptor-mediated antioxidant and neuroprotective effects of ropinirole, a dopamine agonist. Brain Res 838: 51-59, 1999.
    • (1999) Brain Res , vol.838 , pp. 51-59
    • Iida, M.1    Miyazaki, I.2    Tanaka, K.3    Kabuto, H.4    Iwata-Ichikawa, E.5    Ogawa, N.6
  • 32
    • 0023616456 scopus 로고
    • Vitamin E remains the major lipid-soluble, chain-breaking antioxidant in human plasma even in individuals suffering severe vitamin E deficiency
    • Ingold KU, Webb AC, Witter D, Burton GW, Metcalfe TA, and Muller DP. Vitamin E remains the major lipid-soluble, chain-breaking antioxidant in human plasma even in individuals suffering severe vitamin E deficiency. Arch Biochem Biophys 259: 224-225, 1987.
    • (1987) Arch Biochem Biophys , vol.259 , pp. 224-225
    • Ingold, K.U.1    Webb, A.C.2    Witter, D.3    Burton, G.W.4    Metcalfe, T.A.5    Muller, D.P.6
  • 33
    • 0037237927 scopus 로고    scopus 로고
    • Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
    • Ischiropoulos H and Beckman JS. Oxidative stress and nitration in neurodegeneration: cause, effect, or association? J Clin Invest 111: 163-169, 2003.
    • (2003) J Clin Invest , vol.111 , pp. 163-169
    • Ischiropoulos, H.1    Beckman, J.S.2
  • 34
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion S36-S38
    • Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol 53 Suppl 3: S26-S36; discussion S36-S38, 2003.
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 40
    • 0032522304 scopus 로고    scopus 로고
    • Electron transport-linked ubiquinone-dependent recycling of α-tocopherol inhibits autooxidation of mitochondrial membranes
    • Lass A and Sohal RS. Electron transport-linked ubiquinone-dependent recycling of α-tocopherol inhibits autooxidation of mitochondrial membranes. Arch Biochem Biophys 352: 229-236, 1998.
    • (1998) Arch Biochem Biophys , vol.352 , pp. 229-236
    • Lass, A.1    Sohal, R.S.2
  • 42
    • 0034851553 scopus 로고    scopus 로고
    • Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic neurodegeneration
    • Levites Y, Weinreb O, Maor G, Youdim MB, and Mandel S. Green tea polyphenol (-)-epigallocatechin-3-gallate prevents N-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced dopaminergic neurodegeneration. J Neurochem 78: 1073-1082, 2001.
    • (2001) J Neurochem , vol.78 , pp. 1073-1082
    • Levites, Y.1    Weinreb, O.2    Maor, G.3    Youdim, M.B.4    Mandel, S.5
  • 43
    • 0033789565 scopus 로고    scopus 로고
    • Free radical pathways in CNS injury
    • Lewén A, Matz P, and Chan PH. Free radical pathways in CNS injury. J Neurotrauma 17: 871-890, 2000.
    • (2000) J Neurotrauma , vol.17 , pp. 871-890
    • Lewén, A.1    Matz, P.2    Chan, P.H.3
  • 44
    • 0036161352 scopus 로고    scopus 로고
    • Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical
    • Li XJ, Gu J, Lu SD, and Sun FY. Melatonin attenuates MPTP-induced dopaminergic neuronal injury associated with scavenging hydroxyl radical. J Pineal Res 32: 47-52, 2002.
    • (2002) J Pineal Res , vol.32 , pp. 47-52
    • Li, X.J.1    Gu, J.2    Lu, S.D.3    Sun, F.Y.4
  • 45
    • 1642382889 scopus 로고    scopus 로고
    • Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3-gallate: Implications for neurodegenerative diseases
    • Mandel S, Weinreb O, Amit T, and Youdim MB. Cell signaling pathways in the neuroprotective actions of the green tea polyphenol (-)-epigallocatechin-3- gallate: implications for neurodegenerative diseases. J Neurochem 88: 1555-1569, 2004.
    • (2004) J Neurochem , vol.88 , pp. 1555-1569
    • Mandel, S.1    Weinreb, O.2    Amit, T.3    Youdim, M.B.4
  • 46
    • 0022548599 scopus 로고
    • Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)
    • Martinovits G, Melamed E, Cohen O, Rosenthal J, and Uzzan A. Systemic administration of antioxidants does not protect mice against the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP). Neurosci Lett 69: 192-197, 1986.
    • (1986) Neurosci Lett , vol.69 , pp. 192-197
    • Martinovits, G.1    Melamed, E.2    Cohen, O.3    Rosenthal, J.4    Uzzan, A.5
  • 47
    • 0001115172 scopus 로고
    • Serum coenzyme Q-10 level in Parkinson syndrome
    • edited by Folkers K, Littarru GP, and Yamagami, T. Amsterdam: Elsevier Science Publishers
    • Matsubara T, Azuma T, Yoshida S, and Yamagami T. Serum coenzyme Q-10 level in Parkinson syndrome. In: Biomedical and Clinical Aspects of Coenzyme Q, edited by Folkers K, Littarru GP, and Yamagami, T. Amsterdam: Elsevier Science Publishers, 1991, pp. 159-166.
    • (1991) Biomedical and Clinical Aspects of Coenzyme Q , pp. 159-166
    • Matsubara, T.1    Azuma, T.2    Yoshida, S.3    Yamagami, T.4
  • 49
    • 0025831475 scopus 로고
    • Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: Preliminary observations
    • Mihatsch W, Russ H, Gerlach M, Riederer P, and Przuntek H. Treatment with antioxidants does not prevent loss of dopamine in the striatum of MPTP-treated common marmosets: preliminary observations. J Neural Transm Park Dis Dement Sect 3: 73-78, 1991.
    • (1991) J Neural Transm Park Dis Dement Sect , vol.3 , pp. 73-78
    • Mihatsch, W.1    Russ, H.2    Gerlach, M.3    Riederer, P.4    Przuntek, H.5
  • 51
    • 0035824271 scopus 로고    scopus 로고
    • Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway
    • Morgan WW and Nelson JF. Chronic administration of pharmacological levels of melatonin does not ameliorate the MPTP-induced degeneration of the nigrostriatal pathway. Brain Res 921: 115-121, 2001.
    • (2001) Brain Res , vol.921 , pp. 115-121
    • Morgan, W.W.1    Nelson, J.F.2
  • 52
    • 0033669158 scopus 로고    scopus 로고
    • The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease
    • Moussaoui S, Obinu MC, Daniel N, Reibaud M, Blanchard V, and Imperato A. The antioxidant ebselen prevents neurotoxicity and clinical symptoms in a primate model of Parkinson's disease. Exp Neurol 166: 235-245, 2000.
    • (2000) Exp Neurol , vol.166 , pp. 235-245
    • Moussaoui, S.1    Obinu, M.C.2    Daniel, N.3    Reibaud, M.4    Blanchard, V.5    Imperato, A.6
  • 53
    • 0031801548 scopus 로고    scopus 로고
    • Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced neurotoxicity in mice
    • Muralikrishnan D and Mohanakumar KP. Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice. FASEB J 12: 905-912, 1998.
    • (1998) FASEB J , vol.12 , pp. 905-912
    • Muralikrishnan, D.1    Mohanakumar, K.P.2
  • 54
    • 0036292827 scopus 로고    scopus 로고
    • Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells
    • Nie G, Cao Y, and Zhao B. Protective effects of green tea polyphenols and their major component, (-)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells. Redox Rep 7: 171-177, 2002.
    • (2002) Redox Rep , vol.7 , pp. 171-177
    • Nie, G.1    Cao, Y.2    Zhao, B.3
  • 55
    • 0029809527 scopus 로고    scopus 로고
    • Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: Dose-response study and correlations with plasma levels
    • Pappert EJ, Tangney CC, Goetz CG, Ling ZD, Lipton JW, Stebbins GT, and Carvey PM. Alpha-tocopherol in the ventricular cerebrospinal fluid of Parkinson's disease patients: dose-response study and correlations with plasma levels. Neurology 47: 1037-1042, 1996.
    • (1996) Neurology , vol.47 , pp. 1037-1042
    • Pappert, E.J.1    Tangney, C.C.2    Goetz, C.G.3    Ling, Z.D.4    Lipton, J.W.5    Stebbins, G.T.6    Carvey, P.M.7
  • 56
    • 0027530638 scopus 로고
    • Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease
    • Parkinson Study Group. Effects of tocopherol and deprenyl on the progression of disability in early Parkinson's disease. N Engl J Med 328: 176-183, 1993.
    • (1993) N Engl J Med , vol.328 , pp. 176-183
  • 57
    • 0037012478 scopus 로고    scopus 로고
    • Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression
    • Parkinson Study Group. Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 287: 1653-1661, 2002.
    • (2002) JAMA , vol.287 , pp. 1653-1661
  • 58
    • 0022400573 scopus 로고
    • Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine by four different antioxidants in the mouse
    • Perry TL, Yong VW, Clavier RM, Jones K, Wright JM, Foulks JG, and Wall RA. Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine by four different antioxidants in the mouse. Neurosci Lett 60: 109-114, 1985.
    • (1985) Neurosci Lett , vol.60 , pp. 109-114
    • Perry, T.L.1    Yong, V.W.2    Clavier, R.M.3    Jones, K.4    Wright, J.M.5    Foulks, J.G.6    Wall, R.A.7
  • 59
    • 0023638144 scopus 로고
    • Alpha-tocopherol and betacarotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Perry TL, Yong VW, Hansen S, Jones K, Bergeron C, Foulks JG, and Wright JM. Alpha-tocopherol and betacarotene do not protect marmosets against the dopaminergic neurotoxicity of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurol Sci 81:321-331, 1987.
    • (1987) J Neurol Sci , vol.81 , pp. 321-331
    • Perry, T.L.1    Yong, V.W.2    Hansen, S.3    Jones, K.4    Bergeron, C.5    Foulks, J.G.6    Wright, J.M.7
  • 60
    • 0030752296 scopus 로고    scopus 로고
    • Melatonin in relation to cellular antioxidative defense mechanisms
    • Reiter RJ, Carneiro RC, and Oh CS. Melatonin in relation to cellular antioxidative defense mechanisms. Horm Metab Res 29: 363-372, 1997.
    • (1997) Horm Metab Res , vol.29 , pp. 363-372
    • Reiter, R.J.1    Carneiro, R.C.2    Oh, C.S.3
  • 61
    • 0035895844 scopus 로고    scopus 로고
    • Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: Behavioral and histochemical evidence
    • Roghani M and Behzadi G. Neuroprotective effect of vitamin E on the early model of Parkinson's disease in rat: behavioral and histochemical evidence. Brain Res 892: 211-217, 2001.
    • (2001) Brain Res , vol.892 , pp. 211-217
    • Roghani, M.1    Behzadi, G.2
  • 62
    • 0000232034 scopus 로고
    • A marker of oxyradical-mediated DNA damage (8-hydroxy-2′- deoxyguanosine) is increased in nigro-striatum of Parkinson's disease brain
    • Sanchez-Ramos JR, Overvil E, and Ames BN. A marker of oxyradical-mediated DNA damage (8-hydroxy-2′-deoxyguanosine) is increased in nigro-striatum of Parkinson's disease brain. Neurodegeneration 3: 197-204, 1994.
    • (1994) Neurodegeneration , vol.3 , pp. 197-204
    • Sanchez-Ramos, J.R.1    Overvil, E.2    Ames, B.N.3
  • 64
    • 0028978106 scopus 로고
    • Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity
    • Schulz JB, Henshaw DR, Matthews RT, and Beal MF. Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity. Exp Neurol 132: 279-283, 1995.
    • (1995) Exp Neurol , vol.132 , pp. 279-283
    • Schulz, J.B.1    Henshaw, D.R.2    Matthews, R.T.3    Beal, M.F.4
  • 65
    • 0346849912 scopus 로고    scopus 로고
    • Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lesion in rats
    • Shachar DB, Kahana N, Kampel V, Warshawsky A, and Youdim MB. Neuroprotection by a novel brain permeable iron chelator, VK-28, against 6-hydroxydopamine lesion in rats. Neuropharmacology 46: 254-263, 2004.
    • (2004) Neuropharmacology , vol.46 , pp. 254-263
    • Shachar, D.B.1    Kahana, N.2    Kampel, V.3    Warshawsky, A.4    Youdim, M.B.5
  • 67
    • 0141761467 scopus 로고    scopus 로고
    • 10 in neurodegenerative diseases
    • 10 in neurodegenerative diseases. Curr Med Chem 10: 1917-1921, 2003.
    • (2003) Curr Med Chem , vol.10 , pp. 1917-1921
    • Shults, C.W.1
  • 68
    • 0030612117 scopus 로고    scopus 로고
    • 10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects
    • 10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects. Ann Neurol 42: 261-264, 1997.
    • (1997) Ann Neurol , vol.42 , pp. 261-264
    • Shults, C.W.1    Haas, R.H.2    Passov, D.3    Beal, M.F.4
  • 70
    • 0031746550 scopus 로고    scopus 로고
    • Alpha tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study
    • Parkinson Study Group
    • Vatassery GT, Fahn S, and Kuskowski MA. Alpha tocopherol in CSF of subjects taking high-dose vitamin E in the DATATOP study. Parkinson Study Group. Neurology 50: 1900-1902, 1998.
    • (1998) Neurology , vol.50 , pp. 1900-1902
    • Vatassery, G.T.1    Fahn, S.2    Kuskowski, M.A.3
  • 71
    • 0032744787 scopus 로고    scopus 로고
    • High doses of vitamin E in the treatment of disorders of the central nervous system in the aged
    • Vatassery GT, Bauer T, and Dysken M. High doses of vitamin E in the treatment of disorders of the central nervous system in the aged. Am J Clin Nutr 70: 793-801, 1999.
    • (1999) Am J Clin Nutr , vol.70 , pp. 793-801
    • Vatassery, G.T.1    Bauer, T.2    Dysken, M.3
  • 73
    • 0032973751 scopus 로고    scopus 로고
    • A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease
    • Willis GL and Armstrong SM. A therapeutic role for melatonin antagonism in experimental models of Parkinson's disease. Physiol Behav 66: 785-795, 1999.
    • (1999) Physiol Behav , vol.66 , pp. 785-795
    • Willis, G.L.1    Armstrong, S.M.2
  • 74
    • 0036018104 scopus 로고    scopus 로고
    • The dopamine agonist cabergoline provides neuroprotection by activation of the glutathione system and scavenging free radicals
    • Yoshioka M, Tanaka K, Miyazaki I, Fujita N, Higashi Y, Asanuma M, and Ogawa N. The dopamine agonist cabergoline provides neuroprotection by activation of the glutathione system and scavenging free radicals. Neurosci Res 43: 259-267, 2002.
    • (2002) Neurosci Res , vol.43 , pp. 259-267
    • Yoshioka, M.1    Tanaka, K.2    Miyazaki, I.3    Fujita, N.4    Higashi, Y.5    Asanuma, M.6    Ogawa, N.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.