Ascorbate in the rat lens: Dependence on dietary intake

Ophthalmic Research

Volumn 37, Issue 3, 2005, Pages 142-149

  Mody Jr , Vino C ^a   Kakar, Manoj ^a   Elfving, Åse ^b   Söderberg, Per G ^a   Löfgren, Stefan ^a  

^a ST ERIK S EYE HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Ascorbate; Rat lens

Indexed keywords

ASCORBIC ACID; PHOSPHORIC ACID DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALIBRATION; CATARACT; CONFIDENCE INTERVAL; CONTROLLED STUDY; DIETARY INTAKE; DISEASE COURSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HOMOGENATE; ION EXCHANGE; LENS; NONHUMAN; PRIORITY JOURNAL; RAT; REGRESSION ANALYSIS;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DIET; EATING; FEMALE; LENS, CRYSTALLINE; RATS; RATS, SPRAGUE-DAWLEY; SPECIMEN HANDLING;

EID: 17644421201     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000085534     Document Type: Article

References (39)

1. Halliwell B, Gutteridge JMC: Free Radicals in Biology and Medicine. New York, Oxford University Press, 1999, chapt 3: Antioxidant defenses, pp 200-208.
2. Committee on Animal Nutrition NRC: Ascorbic Acid. Vitamin Tolerance of Animals. Washington, National Academy Press, 1987, pp 36-42.
3. Long C (ed): The Component Parts of the Eye. Biochemists' Handbook. Princeton, Van Nostrand, 1961, pp 706-715.
4. Varma SD: Scientific basis for medical therapy of cataracts by anti-oxidants. Am J Clin Nutr 1991;53:335S-345S.
5. Reddy VN, Giblin FJ, Lin LR, Chakrapani B: The effect of aqueous humor ascorbate on ultraviolet-B-induced DNA damage in lens epithelium. Invest Ophthalmol Vis Sci 1998;39:344-350.
6. Sies H, Stahl W, Sundquist A: Antioxidant functions of vitamins. Ann NY Acad Sci 1992;669:7-20.
7. Varma SD, Srivastava VK, Richards RD: Photoperoxidation in lens and cataract formation. Ophthalmic Res 1982;14:167-175.
8. Tung WH, Chylack LT, Andley UP: Lens hexokinase deactivation by near-UV irradiation. Curr Eye Res 1988;7:257-263.
9. Reddy GB, Bhat KS: Protection against UVB inactivation (in vitro) of rat lens enzymes by natural antioxidants. Mol Cell Biochem 1999;194:41-45.
10. Devamanoharan PS, Henein M, Morris S, Ramachandran S, Richards RD, Varma SD: Prevention of selenite cataract by vitamin C. Exp Eye Res 1991;52:563-568.
11. Hegde KR, Varma SD: Protective effect of ascorbate against oxidative stress in the mouse lens. Biochim Biophys Acta 2004;1670:12-18.
12. Sasaki H, Hata I, Shui YB, Kojima M, Sakamoto A, Kawakami Y, Takahashi N, Sasaki K: The effect of physiological levels of antioxidants on human lens epithelial cells and rat lenses damaged by UV irradiation (ARVO abstract). Invest Ophthalmol Vis Sci 2000;41:4.
13. Jacques PF, Taylor A, Hankinson SE, Willett WC, Mahnken B, Lee Y, Vaid K, Lahav M: Long-term vitamin C supplement use and prevalence of early age-related lens opacities. Am J Clin Nutr 1997;66:911-916.
14. Leske MC, Chylac L, Suh-Yuh W: The lens opacities case-control study: Risk factors for cataract. Arch Ophthalmol 1991;109:244-251.
15. Robertson J, Donner A, Trevithick J: A possible role for vitamins C and E in cataract prevention. Am J Clin Nutr 1991;53:346S-351S.
16. Tessier F, Moreaux V, Birlouez-Aragon I, Junes P, Mondon H: Decrease in vitamin C concentration in human lenses during cataract progression. Int J Vitam Nutr Res 1998;68:309-315.
17. Ringvold A: Quenching of UV-induced fluorescence by ascorbic acid in the aqueous humor. Acta Ophthalmol Scand 1995;73:529-533.
18. Garland D: Ascorbic acid and the eye. Am J Clin Nutr 1991;54:1198S-1202S.
19. Müller HK: Reducing property of aqueous humor. Nature (Lond) 1933;132:280-281.
20. Omaye ST, Turnbull JD, Sanberlica HE: Selected methods for the determination of ascorbic acid in animal cells, tissue and fluids. Methods Enzymol 1979;62:3-11.
21. Richer SP, Rose RC: Water soluble antioxidants in mammalian aqueous humor: Interaction with UVB and hydrogen peroxide. Vision Res 1998;38:2881-2888.
22. Schell DA, Bode AM: Measurement of ascorbic acid and dehydroascorbic acid in mammalian tissues utilizing HPLC and electrochemical detection. Biochem Chromatogr 1993;7:267-272.
23. Blondin J, Baragi V, Schwartz E, Sadowski JA, Taylor A: Delay of UV-induced eye lens protein damage in guinea pigs by dietary ascorbate. J Free Radic Biol Med 1986;2:275-281.
24. Berger J, Shepard D, Morrow F, Taylor A: Relationship between dietary intake and tissue levels of reduced and total vitamin C in the nonscorbutic guinea pig. J Nutr 1989;119:734-740.
25. Watson DG, Iqbal Z, Midgley JM, Pryce-Jones H, Morrison L, Dutton GN, Karditsas S, Wilson W: Measurement of ascorbic acid in human aqueous humor and plasma and bovine aqueous humor by high-performance liquid chromatography with electrochemical detection. J Pharm Biomed Anal 1993;11:389-392.
26. Hallström A, Carlsson A, Hillered L, Ungerstedt U: Simultaneous determination of lactate, pyruvate, and ascorbate in microdialysis samples from rat brain, blood, fat, and muscle using high-performance liquid chromatography. J Pharmacol Methods 1989;22:113-124.
27. Ringvold A, Anderssen E, Kjonniksen I: Distribution of ascorbate in the anterior bovine eye. Invest Ophthalmol Vis Sci 2000;41:20-23.
28. Takano S, Ishiwata S, Nakazawa M, Mizugaki M, Tamai M: Determination of ascorbic acid in human vitreous humor by high-performance liquid chromatography with UV detection. Curr Eye Res 1997;16:589-594.
29. Mody V, Kakar M, Elfving Å, Löfgren S, Ungerstedt U, Söderberg PG: Determination of ascorbate in the ocular lens (EVER abstract). Ophthalmic Res 2001;33(suppl 1):135.
30. McGahan MC: Ascorbic acid levels in aqueous and vitreous humors of the rabbit: Effects of inflammation and ceruloplasmin. Exp Eye Res 1985;41:291-298.
31. Hiraki S, Yamada Y, Ishida T, Nakamura Y, Motose K: The analysis of aqueous humor in albino rabbits by high performance liquid chromatography. Nihon Ganka Kiyo 1984;35:393-398.
32. Rose RC, Nahrwold DL: Ascorbic acid analysis in biological fluids. Anal Biochem 1982;123:389-393.
33. Lloyd L, Warner FP: Quantitative reversed phase HPLC analysis of L-ascorbic acid (vitamin C) and identification of its degradation products. Chromatographia 1987;24:371-376.
34. Washko PW, Welch RW, Dhariwal KR, Wang Y, Levine M: Ascorbic acid and dehydroascorbic acid analyses in biological samples. Anal Biochem 1992;204:1-14.
35. Taylor A, Jahngen-Hodge J, Smith DE, Palmer VJ, Dallal GE, Lipman RD, Padhye N, Frei B: Dietary restriction delays cataract and reduces ascorbate levels in Emory mice. Exp Eye Res 1995;61:55-62.
36. Taylor A, Jacques PF, Nowell T, Perrone G, Blumberg J, Handelman G, Jozwiak B, Nadler D: Vitamin C in human and guinea pig aqueous, lens and plasma in relation to intake. Curr Eye Res 1997;16:857-864.
37. Koshiishi I, Mamura Y, Liu J, Imanari T: Evaluation of an acidic deproteinization for the measurement of ascorbate and dehydroascorbate in plasma samples. Clin Chem 1998;44:863-868.
38. Schmidt K, Oberritter H, Bruchelt G, Hagmaier V, Hornig D: Studies on the metabolic conversion of ascorbate. Int J Vitam Nutr Res 1983;53:77-85.
39. Johnsen H, Ringvold A, Blika S: Ascorbic acid determination in serum and aqueous humor by high-performance liquid chromatography. Acta Ophthalmol 1985;63:31-34.