Mutations in anionic trypsinogen gene are not associated with tropical calcific pancreatitis [3]

Gut

Volumn 54, Issue 5, 2005, Pages 728-729

  Idris, M M ^a   Bhaskar, S ^a   Reddy, D N ^b   Mani, K R ^a   Rao, G V ^b   Singh, L ^a   Chandak, G R ^a  

^a CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

^b ASIAN INSTITUTE OF GASTROENTEROLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSMEMBRANE CONDUCTANCE REGULATOR; TRYPSINOGEN;

CLINICAL ARTICLE; CONTROLLED STUDY; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LETTER; PANCREATITIS; PATHOGENESIS; PRIORITY JOURNAL; PROMOTER REGION; PRSS1 GENE; SPINK1 GENE; TROPICAL CALCIFIC PANCREATITIS;

CALCINOSIS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MUTATION; PANCREATITIS; TRYPSIN; TRYPSINOGEN;

EID: 17644420759     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2004.055335     Document Type: Letter

References (9)

1. Whitcomb DC, Garry MV, Preston RA, et al. Hereditary pancreatitis caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141-5.
2. Gorry MC, Gabbaizedeh D, Furey W, et al. Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology 1997;113:1063-8.
3. Witt H, Luck W, Hennies HC, et al. Mutations in the gene encoding the serine protease inhibitor Kazal type I are associated with chronic pancreatitis. Nat Genet 2000;25:213-16.
4. Sharer N, Schwarz M, Malone G, et al. Mutations in the cystic fibrosis gene in patients with chronic prancreatitis. N Engl J Med 1998;339:645-52.
5. Cohn JA, Friedman KJ, Noone PG, et al. Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis. N Engl J Med 1998;339:653-8.
6. Chandak GR, Idris MM, Reddy DN, et al. Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis. J Med Genet 2002;39:347-51.
7. Bhatia E, Chowdhuri G, Sikora SS, et al. Tropical calcific pancreatitis: strong association with SPINK1 trypsin inhibitor mutations. Gastroenterology 2002;123:1020-5.
8. Schneider A, Suman A, Rossi L, et al. SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh. Gastroenterology 2002;123:1026-30.
9. Chen J, Audrezet M, Mercier B, et al. Exclusion of anionic trypsinogen and mesotrypsinogen involvement in hereditary pancreatitis without cationic trypsinogen gene mutations. Scand J Gastroenterol 1999;8:831-2.