Effect of dihydroartemisinin on proliferation of human lung adenocarcinoma cell line A549

Chinese Journal of Lung Cancer

Volumn 8, Issue 2, 2005, Pages 85-88

  Chen, Weiqiang ^a   Qi, Haowen ^b   Wu, Changgui ^a   Cui, Yan ^b   Liu, Bin ^b   Li, Yan ^b   Wu, Junzhen ^b  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b NONE

Author keywords

Dihydroartemisinin; Lung neoplasms; Nude mice

Indexed keywords

ANTINEOPLASTIC AGENT; DIHYDROARTEMISININ;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL COUNT; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA CONTENT; DRUG EFFECT; FLOW CYTOMETRY; GROWTH CURVE; HUMAN; HUMAN CELL; IC 50; LUNG ADENOCARCINOMA; MOUSE; NONHUMAN; NUDE MOUSE;

EID: 17644420363     PISSN: 10093419     EISSN: 19996187     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Chen HH, Zhou HJ, Fang X. Inhibition of human cancer cell line growth and human umbilical vein endothelial cell angiogenesis by artemisinin derivatives in vitro. Pharmacol Res, 2003, 48(3): 231-236.
2. Posner GH, Northrop J, Paik IH, et al. New chemical and biological aspects of artemisinin-derived trioxane dimers. Bioorg Med Chem, 2002, 10(1): 227-232.
3. Efferth T, Olbrich A, Bauer R. mRNA expression profiles for the response of human tumor cell lines to the antimalarial drugs artesunate, arteether, and artemether. Biochem Pharmacol, 2002, 64 (4): 617-623.
4. Jeyadevan JP, Bray PG, Chadwick J , et al. Antimalarial and antitumor evaluation of novel C-10 non-acetal dimers of 10beta-(2-hydroxyethyl) deoxoartemisinin. J Med Chem, 2004, 47(5): 1290-1298.
5. Posner GH, Paik IH, Sur S, et al. Orally active, antimalarial, anticancer, artemisinin-derived trioxane dimers with high stability and efficacy. J Med Chem, 2003, 46(6): 1060-1065.
6. Sadava D, Phillips T, Lin C, et al. Transferrin overcomes drug resistance to artemisinin in human small-cell lung carcinoma cells. Cancer Lett, 2002, 179(2): 151-156.
7. Galal AM, Ross SA, ElSohly MA, et al. Deoxyartemisinin derivatives from photooxygenatton of anhydrodeoxydihydroartemisinin and their cytotoxic evaluation. J Nat Prod, 2002, 65(2): 184-188.
8. Singh NP, Lai H. Selective toxicity of dihydroartemisinin and holotransferrin toward human breast cancer cells. Life Sci, 2001, 70 (1): 49-56.
9. Zhu HF, Lan L, Zhao SX, et al. Characterization of Human Lung Cancer Cell Line A549 in 615-SCID Mice. Acta Laboratorium Animalis Scientia Sinica, 2003, 11(4): 200-202.