Memantine alleviates toxicity induced by dichlorvos in rats

Journal of Occupational Health

Volumn 47, Issue 2, 2005, Pages 96-101

  Zhou, Zhijun ^a,b   Dai, Xufeng ^a   Gu, Xi'an ^a   Sun, Yunguang ^a   Zheng, Guang ^a   Zheng, Jie ^a  

^a FUDAN UNIVERSITY   (China)

^b FUDAN UNIVERSITY   (China)

Author keywords

Dichlorvos; Memantine; NMDA receptor

Indexed keywords

ACETYLCHOLINESTERASE; DICHLORVOS; DIZOCILPINE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; TRITIUM;

ACUTE TOXICITY; ANIMAL MODEL; ARTICLE; BLOOD; BRAIN; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVITY; FASCICULATION; INTOXICATION; MALE; NEUROTOXICITY; NEUROTRANSMISSION; NONHUMAN; RAT; TREATMENT OUTCOME;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; DICHLORVOS; EXCITATORY AMINO ACID ANTAGONISTS; INSECTICIDES; MALE; MEMANTINE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

ANIMALIA; TRITIUM;

EID: 17644410335     PISSN: 13419145     EISSN: None     Source Type: Journal    
DOI: 10.1539/joh.47.96     Document Type: Article

References (25)

1. AN Masuda, M Takatsu, H Morianari and T Ozawa: Sarin poisoning in Tokyo subway. Lancet 345, 1446 (1995)
2. PM Herman, H Van and JH Bueters: Protective activity of adenosine receptor agonists in the treatment of organophosphate poisoning. Trends Pharmacol Sci 20, 438-440 (1999)
3. ZJ Zhou, YP Hu, YG Sun and J Chen: Protective effect of clonidine against toxicity of organophosphorus pesticides. J Occup Health 43, 346-350 (2001)
4. Urbanska EM, Dekundy A, Kleinrok Z, et al. Glutamatergic receptor agonists and brain pathology. In: Kostrzewa RM, ed. Highly selective neurotoxins. Totowa, New Jersey: Humana Press, 1997: 329-354.
5. Y Solberg and M Belkin: The role of excitotoxicity in organophosphorus nerve agents central poisoning. Trends Pharmacol Sci 18, 183-185 (1997)
6. TM Shih and JH McDonough: Neurochemical mechanisms in soman-induced seizures. J Appl Toxicol 17, 255-264 (1997)
7. RC Gupta and WL Kadel: Methyl-parathion acute toxicity: Prophylaxis and therapy with memantine and atropine. Arch Int Pharmacodyn Ther 305, 208-221 (1990)
8. K Masuo, KI Enomoto and T Maeno: Effect of memantine on the frog neuromuscular junction. Eur J Pharmacol 130, 187-195 (1986)
9. MD Youssef: Organophosphorous poisoning and therapeutic agents: clinical profile. Pesticide Safety News 5, 3 (2002)
10. EH Wong, JA Kemp, T Priestley, AR Knight, GN Woodruff and LL Iversen: The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci 83, 7104-7108 (1986)
11. JP Yu: Pain induced by suxamethonium. Foreign Medical Science-Section Surgery 8, 115 (1981) (in Chinese)
12. GL Ellman, KD Courtney, V Andres and RM Feather-Stone: A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7, 88-95 (1961)
13. OH Lowry, NJ Rosebrough, AL Farr and RJ Randall: Protein measurement with folin phenol reagent. J Biol Chem 193, 265-275 (1951)
14. LP Miller, BG Lyeth, LW Jenkins, L Oleniak, D Panchision, RJ Hamn, LL Phillips, CE Dixon and GL Clifton: Excitatory amino acid receptor subtype binding following traumatic brain injury. Brain Research 526, 103-107 (1990)
15. DW Choi, H Monyer, RG Giffard, MP Goldberg and CW Christine: Acute brain injury, NMDA receptors, and hydrogen ions: observations in cortical cell cultures. Adv Exp Med Biol 268, 501-504 (1990)
16. PS Johnson and EK Michaelis: Characterization of organophosphate interactions at N-methyl-D-aspartate receptors in brain synaptic membranes. Mol Pharmacol 41, 750-756 (1992)
17. N Takei and Y Endo: Ca2+ ionophore-induced apoptosis on cultured embryonic rat cortical neurons. Brain Res 652, 65 (1994)
18. R Bullock: Introducing NMDA antagonists into clinical practice: why head injury trials? Br J Clin Pharmacol 34, 396-401 (1992)
19. RC Gupta and WL Kadel: Prevention and antagonism of acute carbofuran intoxication by memantine and atropine. J Toxicol Environ Health 28, 111-122 (1989)
20. RC Gupta and WL Kadel: Methyl parathion acute toxicity: Prophylaxis and therapy with memantine and atropine. Arch Int Pharmacodyn 305, 208-221 (1990)
21. RC Gupta, JT Goad and WL Kadel: Protection and reversal by memantine and atropine of carbofuran-induced changes in biomarkers. Drug Dev Res 28, 153-160 (1993)
22. MJ Mclean, RC Gupta, WD Dettbarn and AW Wamil: Prophylactic and therapeutic efficacy of memantine against seizures produced by soman in the rat. Toxicol Appl Pharmacol 112, 95-103 (1992)
23. HPM van Helden and TJH Bueters: Protective activity of adenosine receptor agonists in the treatment of organophosphate poisoning. Trends Pharmacol Sci 20, 438-441 (1999)
24. I Bregovec, M Maksimovic and V Kilibarda: Adamantane derivatives as potential reactivators of acetylcholinesterase inhibited by organophosphorous compounds. Acta Pharmaceutica 42, 251-253 (1992)
25. XF Dai, G Zheng, YG Sun, J Zheng and ZJ Zhou: Therapeutic effect of memantine against the acute intoxication of dichlorvos. Occup Health & Emerg Rescue 20, 169-172 (2002) (in Chinese)