Analysis of Epstein-Barr virus gene expression upon phorbol ester and hydroxyurea treatment by real-time quantitative PCR

Archives of Virology

Volumn 150, Issue 4, 2005, Pages 755-770

  Pan, Y R ^a   Fang, C Y ^a   Chang, Y S ^b   Chang, H Y ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; HYDROXYUREA; MESSENGER RNA; PHORBOL 13 ACETATE 12 MYRISTATE; PRIMER DNA; VIRUS RNA;

ANIMAL; ARTICLE; CELL LINE; DNA TEMPLATE; DRUG EFFECT; EPSTEIN BARR VIRUS; GENE EXPRESSION REGULATION; GENETICS; METHODOLOGY; POLYMERASE CHAIN REACTION; VIRUS GENOME;

ANIMALS; CELL LINE; DNA PRIMERS; DNA, COMPLEMENTARY; GENE EXPRESSION REGULATION, VIRAL; GENOME, VIRAL; HERPESVIRUS 4, HUMAN; HYDROXYUREA; POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, VIRAL; TEMPLATES, GENETIC; TETRADECANOYLPHORBOL ACETATE;

HUMAN HERPESVIRUS 4;

EID: 17644406750     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-004-0431-7     Document Type: Article

References (20)

1. Baer R, Bankier AT, Biggin MD, Deininger PL, Farrell PJ, Gibson TJ, Hatfull G, Hudson GS, Satchwell SC, Seguin C, Tuffenll P, Barrel B (1984) DNA sequence and expression of the B95-8 Epstein-Barr virus genome. Nature 310: 207-211
2. Chavrier P, Gruffat H, Chevallier-Greco A, Buisson M, Sergeant A (1989) The Epstein-Barr virus (EBV) early promoter DR contains a cis-acting element responsive to the EBV transactivator EB1 and an enhancer with constitutive and inducible activities. J Virol 63: 607-614
3. Chodosh J, Holder VP, Gan YJ, Belgaumi A, Sample J, Sixbey JW (1998) Eradication of latent Epstein-Barr virus by hydroxyurea alters the growth-transformed cell phenotype. J Infect Dis 177: 1194-1201
4. Countryman J, Jenson H, Seibl R, Wolf H, Miller G (1987) Polymorphic proteins encoded within BZLF1 of defective and standard Epstein-Barr viruses disrupt latency. J Virol 61: 3672-3679
5. Fakhari FD, Dittmer DP (2002) Charting latency transcripts in Kaposi's sarcoma-associated herpesvirus by whole-genome real-time quantitative PCR. J Virol 76: 6213-6223
6. Farrell PJ, Bankier A, Seguin C, Deininger P, Barrell BG (1983) Latent and lytic cycle promoters of Epstein-Barr virus. EMBO J 2: 1331-1338
7. Herrmann K, Niedobitek G (2003) Epstein-Barr virus-associated carcinomas: facts and fiction. J Pathol 199: 140-145
8. Hummel M, Kieff E (1982) Epstein-Barr virus RNA. VIII. Viral RNA in permissively infected B95-8 cells. J Virol 43: 262-272
9. Huyghe P, Dassonneville L, Fenaux P, Bailly C (2004) Hydroxyurea-induced apoptosis in an EBV-immortalized lymphoblastoid cell line. Oncol Res 14: 235-245
10. Jiang R, Zhang JL, Satoh Y, Sairenji T (2004) Mechanism for induction of hydroxyurea resistance and loss of latent EBV genome in hydroxyurea-treated Burkitt's lymphoma cell line Raji. J Med Virol 73: 589-595
11. Jones JO, Arvin AM (2003) Microarray analysis of host cell gene transcription in response to varicella-zoster virus infection of human T cells and fibroblasts in vitro and SCIDhu skin xenografts in vivo. J Virol 77: 1268-1280
12. Kawanishi M, Sugawara K, Ito Y (1986) DNA synthesis inhibitors suppress expression of Epstein-Barr virus in chemically activated human lymphoblastoid cells. Intervirology 25: 223-231
13. Leung E, Shenton BK, Jackson G, Gould FK, Yap C, Talbot D (2002) Use of real-time PCR to measure Epstein-Barr virus genomes in whole blood. J Immunol Methods 270: 259-267
14. Lidin BI, Lamon EW (1983) Effects of DNA synthesis inhibitors on early antigen expression following primary infection or superinfection by Epstein-Barr virus. Arch Virol 77: 13-25
15. Macsween KF, Crawford DH (2003) Epstein-Barr virus-recent advances. Lancet Infect Dis 3: 131-140
16. Mellinghoff I, Daibata M, Humphreys RE, Mulder C, Takada K, Sairenji T (1991) Early events in Epstein-Barr virus genome expression after activation: regulation by second messengers of B cell activation. Virology 185: 922-928
17. Niesters HG, van Esser J, Fries E, Wolthers KC, Cornelissen J, Osterhaus AD (2000) Development of a real-time quantitative assay for detection of Epstein-Barr virus. J Clin Microbiol 38: 712-715
18. Novakova Z, Roubal J (1988) Induction of Epstein-Barr virus antigens by hydroxyurea. Acta Virol 32: 160-163
19. Weigel R, Miller G (1985) Latent and viral replicative transcription in vivo from the BamHI K fragment of Epstein-Barr virus DNA. J Virol 54: 501-508
20. Young LS, Murray PG (2003) Epstein-Barr virus and oncogenesis: from latent genes to tumours. Oncogene 22: 5108-5121