Treatment of metastatic gestational choriocarcinoma with oral methotrexate in a combat environment

Obstetrics and Gynecology

Volumn 105, Issue 5 II, 2005, Pages 1250-1254

  Farley, John H ^a   Heathcock, R Brian ^b   Branch, Walter ^b   Larsen, Wilma ^b   Homas, Dallas ^b  

^a TRIPLER ARMY MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHORIONIC GONADOTROPIN BETA SUBUNIT; METHOTREXATE;

ABDOMINAL HYSTERECTOMY; ADULT; ANAMNESIS; ARTICLE; CANCER GRADING; CASE REPORT; CHEMOTHERAPY; CHORIOCARCINOMA; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; CURETTAGE; FEMALE; GESTATION PERIOD; HUMAN; LABORATORY TEST; METASTASIS; PHYSICAL EXAMINATION; PREGNANCY; PRIORITY JOURNAL; SALPINGOOOPHORECTOMY; THORAX RADIOGRAPHY; TREATMENT OUTCOME; ULTRASOUND; VAGINA BLEEDING;

ADMINISTRATION, ORAL; ADULT; BIOPSY, NEEDLE; CHEMOTHERAPY, ADJUVANT; CHORIOCARCINOMA; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; HYSTERECTOMY; IMMUNOHISTOCHEMISTRY; METHOTREXATE; NEOPLASM METASTASIS; NEOPLASM STAGING; POSTPARTUM PERIOD; PREGNANCY; RISK ASSESSMENT; TREATMENT OUTCOME;

EID: 17644402417     PISSN: 00297844     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.AOG.0000157761.18295.43     Document Type: Article

References (17)

1. Smith HO, Qualls CR, Prairie BA, Padilla LA, Rayburn WF, Key CR. Trends in gestational choriocarcinoma: a 27-year perspective. Obstet Gynecol 2003;102:978-87.
2. Yarris JP, Hunter AJ. Roy Hertz, MD (1909-2002): the cure of choriocarcinoma and its impact on the development of chemotherapy for cancer. Gynecol Oncol 2003;89:193-8.
3. Hammond CB, Hertz R, Ross GT, Lipsett MB, Odell WD. Primary chemotherapy for nonmetastatic gestational trophoblastic neoplasms. Am J Obstet Gynecol 1967;98:71-8.
4. Bagshawe KD, Dent J, Newlands ES, Begent RH, Rustin GJ. The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT). Br J Obstet Gynaecol 1989;96:795-802.
5. McNeish IA, Strickland S, Holden L, Rustin GJ, Foskett M, Seckl MJ, et al. Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000. J Clin Oncol 2002;20:1838-44.
6. Barter JF, Soong SJ, Hatch KD, Orr JW Jr, Partridge EC, Austin JM Jr, et al. Treatment of nonmetastatic gestational trophoblastic disease with oral methotrexate. Am J Obstet Gynecol 1987;157:1166-8.
7. Homesley HD, Blessing JA, Rettenmaier M, Capizzi RL, Major FJ, Twiggs LB. Weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease. Obstet Gynecol 1988;72:413-8.
8. Hoffman MS, Fiorica JV, Gleeson NC, Roberts WS, Cavanagh D. A single institution experience with weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease. Gynecol Oncol 1996;60:292-4.
9. Hertz R, Li MC, Spencer DB. Effect of methotrexate therapy upon choriocarcinoma and chorioadenoma. Proc Soc Exp Biol Med 1956;93:361-6.
10. Brewer JI, Gerbie AB, Dolkart RE, Skom JH, Nagle RG, Torok EE. Chemotherapy in trophoblastic diseases. Am J Obstet Gynecol 1964;90:566-78.
11. Hreshchyshyn MM, Graham JB, Holland JF. Treatment of malignant trophoblastic growth in women, with special reference to amethopterin. Am J Obstet Gynecol 1961;81:688-705.
12. Patsner B. Successful treatment of persistent partial mole with oral methotrexate therapy. Gynecol Oncol 1992;46:233-4.
13. Barter JF, Soong SJ, Hatch KD, Orr JW Jr, Partridge EC, Austin JM Jr, et al. Treatment of nonmetastatic gestational trophoblastic disease with sequential intramuscular and oral methotrexate. Gynecol Oncol 1989;33:82-4.
14. Gleeson NC, Finan MA, Fiorica JV, Robert WS, Hoffman MS, Wilson J. Nonmetastatic gestational trophoblastic disease: weekly methotrexate compared with 8-day methotrexate-folinic acid. Eur J Gynaecol Oncol 1993;14:461-5.
15. Kulier R, Gulmezoglu AM, Hofmeyr GJ, Cheng LN, Campana A. Medical methods for first trimester abortion (Cochrane Review). In: The Cochrane Library, Issue 2, 2004. Oxford: Update Software.
16. Homesley HD, Blessing JA, Schlaerth J, Rettenmaier M, Major FJ. Rapid escalation of weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease: a Gynecologic Oncology Group study. Gynecol Oncol 1990;39:305-8.
17. Wong LC, Choo YC, Ma HK. Primary oral etoposide therapy in gestational trophoblastic disease: an update. Cancer 1986;58:14-7.