A catalytic subunit of cyclic AMP-dependent protein kinase, PKAC-1, regulates asexual differentiation in Neurospora crassa

Genes and Genetic Systems

Volumn 80, Issue 1, 2005, Pages 25-34

  Banno, Shinpei ^a   Ochiai, Noriyuki ^a   Noguchi, Rieko ^a   Kimura, Makoto ^b   Yamaguchi, Isamu ^b   Kanzaki, Sei Ichi ^c,d   Murayama, Tadako ^c   Fujimura, Makoto ^a  

^a TOYO UNIVERSITY   (Japan)

^b RIKEN Center for Sustainable Resource Science   (Japan)

^c KANTO GAKUIN UNIVERSITY   (Japan)

^d YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

cAMP; Cell polarity; Conidiation; Neurospora crassa; Protein kinase A

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ARTICLE; CATALYSIS; CONIDIUM; ENZYME ACTIVITY; ENZYME SUBUNIT; FUNGAL VIRULENCE; FUNGUS CULTURE; NEUROSPORA CRASSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CATALYTIC DOMAIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FUNGAL PROTEINS; MORPHOGENESIS; MUTATION; NEUROSPORA CRASSA; SIGNAL TRANSDUCTION;

FUNGI; NEUROSPORA CRASSA;

EID: 17644402110     PISSN: 13417568     EISSN: None     Source Type: Journal    
DOI: 10.1266/ggs.80.25     Document Type: Article

References (37)

1. Adachi, K., and Hamer, J. E. (1998). Divergent cAMP signaling pathways regulate growth and pathogenesis in the rice blast fungus Magnaporthe grisea. Plant Cell 10, 1361-1374.
2. Bailey, L. A., and Ebbole, D. J. (1998). The fluffy gene of Neurospora crassa encodes a Gal4p-type C6 zinc cluster protein required for conidial development. Genetics 148, 1813-1820.
3. Borges-Walmsley, M. I., and Walmsley, A. R. (2000). cAMP signaling in pathogenic fungi: control of dimorphic switching and pathogenicity. Trends Microbiol 8, 133-41.
4. Borkovich, K. A., Alex, L. A., Yarden, O., Freitag, M., Turner, G. E., Read, N. D., Seiler, S., Bell-Pedersen, D., Paietta, J., Plesofsky, N., Plamann, M., Goodrich-Tanrikulu, M., Schulte, U., Mannhaupt, G., Nargang, F. E., Radford, A., Selitrennikoff, C., Galagan, J. E., Dunlap, J. C., Loros, J. J., Catcheside, D., Inoue, H., Aramayo, R., Polymenis, M., Selker, E. U., Sachs, M. S., Marzluf, G. A., Paulsen, I., Davis, R., Ebbole, D. J., Zelter, A., Kalkman, E. R., O'Rourke, R., Bowring, F., Yeadon, J., Ishii, C., Suzuki, K., Sakai, W., and Pratt, R. (2004). Lessons from the genome sequence of Neurospora crassa: tracing the path from genomic blueprint to multicellular organism. Microbiol. Mol. Biol. Rev. 68, 1-108.
5. Bruno, K. S., Aramayo, R., Minke, P. F., Metzenberg, R. L., and Plamann, M. (1996). Loss of growth polarity and mislocalization of septa in a Neurospora mutant altered in the regulatory subunit of cAMP-dependent protein kinase. EMBO J. 15, 5772-5782.
6. Choi, W., and Dean, R. A. (1997). The adenylate cyclase gene MAC1 of Magnaporthe grisea controls appressorium formation and other aspects of growth and development. Plant Cell 9, 1973-1983.
7. Cortat, M., and Turian, G. (1974). Conidiation of Neurospora crassa in submerged culture without mycelial phase. Arch. Microbiol. 95, 305-309.
8. Cruz, A. K., Terenzi, H. F., and Jorge, J. A. (1988). Cyclic AMP-dependent, constitutive thermotolerance in the adenylate cyclase-deficient cr-1 (crisp) mutant of Neurospora crassa. Curr. Genet. 13, 451-454.
9. Davis, R. H., and de Serres, F. J. (1970) Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol. 17, 79-143.
10. De Serres, F. J., Inoue, H., and Schubach, M. E. (1980) Mutagenesis at the ad-3A and ad-3B loci in haploid UV-sensitive strains of Neurospora crassa, I. Development of isogenic strains and spontaneous mutability. Mutation Res. 71, 53-65.
11. D'Souza, C. A., and Heitman, J. (2001). Conserved cAMP signaling cascades regulate fungal development and virulence. FEMS Microbiol. Rev. 25, 349-364.
12. Durrenberger, F., Wong, K., and Kronstad, J. W. (1998). Identification of a cAMP-dependent protein kinase catalytic subunit required for virulence and morphogenesis in Ustilago maydis. Proc. Natl. Acad. Sci. U S A 95, 5684-5689.
13. Gold, S. E., Brogdon, S. M., Mayorga, M. E., and Kronstad, J. W. (1997). The Ustilago maydis regulatory subunit of a cAMP-dependent protein kinase is required for gall formation in maize. Plant Cell 9, 1585-1594.
14. Gorovits, R., and Yarden, O. (2003). Environmental suppression of Neurospora crassa cot-1 hyperbranching: a link between COT1 kinase and stress sensing. Eukaryot. Cell 2, 699-707.
15. Ito, S., Matsui, Y., Toh-e, A., Harashima T., and H. Inoue (1997). Isolation and characterization of the krev-1 gene, a novel member of ras superfamily in Neurospora crassa: involvement in sexual cycle progression. Mol. Gen. Genet. 255, 429-437.
16. Ivey, F. D., Kays, A. M., and Borkovich, K. A. (2002). Shared and independent roles for a Galpha(i) protein and adenylate cyclase in regulating development and stress responses in Neurospora crassa. Eukaryot. Cell 1, 634-642.
17. Kays, A. M., Rowley, P. S., Baasiri, R. A., and Borkovich, K. A. (2000). Regulation of conidiation and adenylate cyclase levels by the Galpha protein GNA-3 in Neurospora crassa. Mol. Cell. Biol. 20, 7693-7705.
18. Kronstad, J., De Maria, A. D., Funnell, D., Laidlaw, R. D., Lee, N., de Sa, M. M., and Ramesh, M. (1998). Signaling via cAMP in fungi: interconnections with mitogen-activated protein kinase pathways. Arch. Microbiol. 170, 395-404.
19. Lee, N., D'Souza, C. A., and Kronstad, J. W. (2003). Of smuts, blasts, mildews, and blights: cAMP signaling in phytopathogenic fungi. Annu. Rev. Phytopathol. 41, 399-427.
20. Lengeler, K. B., Davidson, R. C., D'Souza, C., Harashima, T., Shen, W. C., Wang, P., Pan, X., Waugh, M., and Heitman, J. (2000). Signal transduction cascades regulating fungal development and virulence. Microbiol. Mol. Biol. Rev. 64, 746-785.
21. Madi, L., McBride, S. A., Bailey, L. A., and Ebbole, D. J. (1997). rco-3, a gene involved in glucose transport and conidiation in Neurospora crassa. Genetics 146, 499-508.
22. Mitchell, T. K., and Dean, R. A. (1995). The cAMP-dependent protein kinase catalytic subunit is required for appressorium formation and pathogenesis by the rice blast pathogen Magnaporthe grisea. Plant Cell 7, 1869-1878.
23. Ochiai, N., Fujimura, M., Motoyama, T., Ichiishi, A., Usami, R., Horikoshi, K., and Yamaguchi, I. (2001). Characterization of mutations in the two-component histidine kinase gene that confer fludioxonil resistance and osmotic sensitivity in the os-1 mutants of Neurospora crassa. Pest. Manag. Sci. 57, 437-442.
24. Pan, X., and Heitman, J. (1999). Cyclic AMP-dependent protein kinase regulates pseudohyphal differentiation in Saccharomyces cerevisiae. Mol. Cell Biol. 19, 4874-4887.
25. Robertson, L. S., and Fink, G. R. (1998). The three yeast A kinases have specific signaling functions in pseudohyphal growth. Proc. Natl. Acad. Sci. U S A 95, 13783-13787.
26. Rosenberg, G., and Pall, M. L. (1979). Properties of two cyclic nucleotide-deficient mutants of Neurospora crassa. J. Bacteriol. 137, 1140-1144.
27. Selker, E. U. (1990) Premeiotic instability of repeated sequences in Neurospora crassa. Ann. Rev. Genet., 224, 579-613.
28. Tamaru, H., and Inoue, H. (1989). Isolation and characterization of a laccase-derepressed mutant of Neurospora crassa. J. Bacteriol. 171, 6288-6293.
29. Terenzi, H. F., Flawia, M. M., and Torres, H. N. (1974). A Neurospora crassa morphological mutant showing reduced adenylate cyclase activity. Biochem. Biophys. Res. Commun. 58, 990-996.
30. Thevelein, J. M., and de Winde, J. H. (1999). Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 33, 904-918.
31. Toda, T., Cameron, S., Sass, P., Zoller, M., and Wigler, M. (1987). Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell 50, 277-287.
32. Vogel, H. J. (1964). Distribution of lysine pathways among fungi: evolutionary implications. American Naturalist 98, 435-446.
33. Vollmer, S. J., and Yanofsky, C. (1986). Efficient cloning of genes of Neurospora crassa. Proc. Natl. Acad. Sci. USA 83, 4869-4873.
34. Xu, J. R., and Hamer, J. E. (1996). MAP kinase and cAMP signaling regulate infection structure formation and pathogenic growth in the rice blast fungus Magnaporthe grisea. Genes Dev. 10, 2696-2706.
35. Yang, Q., Poole, S. I., and Borkovich, K. A. (2002). A G-protein beta subunit required for sexual and vegetative development and maintenance of normal G alpha protein levels in Neurospora crassa. Eukaryot. Cell 1, 378-390.
36. Yang, Z., and Dickman, M. B. (1999). Colletotrichum trifolii mutants disrupted in the catalytic subunit of cAMP-dependent protein kinase are nonpathogenic. Mol. Plant Microbe Interact. 12, 430-439.
37. Yarden, O., Plamann, M., Ebbole, D. J., and Yanofsky, C. (1992). cot-1, a gene required for hyphal elongation in Neurospora crassa, encodes a protein kinase. EMBO J. 11, 2159-2166.