Novel fluorescence-based integrated sensor for chemical and biological agent detection

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 5617, Issue , 2004, Pages 353-363

  Frye Mason, Greg ^a   Leuschen, Martin ^a   Wald, Lara ^a   Paul, Kateri ^b   Hancock, Lawrence F ^b   Fagan, Steve ^b   Krouse, Justin ^a   Hutchinson, Kira ^c  

^a ICx Technologies   (United States)

^b Nomadics Inc   (United States)

^c Nomadics Inc   (United States)

Author keywords

Biological warfare; Chemical warfare agent; Chromophore; CW; Fluorescence; LED; Light emitting diode; SUVOS; TIC; Toxic industrial chemical

Indexed keywords

BIOLOGICAL WARFARE (BW); CHEMICAL WARFARE (CW) AGENTS; SEMICONDUCTOR UV OPTICAL SOURCES (SUVOS) PROGRAM; TOXIC INDUSTRIAL CHEMICAL (TIC);

CHEMICAL SENSORS; CHROMOPHORES; FLUORESCENCE; LIGHT EMITTING DIODES; NEUROLOGY; SENSITIVITY ANALYSIS; TOXICITY; ULTRAVIOLET RADIATION;

BIOSENSORS;

EID: 17644388428     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.581275     Document Type: Conference Paper

References (14)

1. Yang, J. S. and Swager, T.M., 1998a. "Porous Shape Persistent Fluorescent Polymer Films: An Approach to TNT Sensory Materials," J. Am. Chem. Soc., 120, 5321-5322; Yang, J. S. and Swager, T.M., 1998b. "Fluorescent Porous Polymer Films as TNT Chemosensors: Electronic and Structural Effects," J. Am. Chem. Soc., 120, 11864-11873; Zhou, Q. and Swager, T., 1995. "Methodology for Enhancing the Sensitivity of Fluorescent Chemosensors: Energy Migration in Conjugated Polymers," J. Am. Chem. Soc., 117, 7017-7018.
2. Yang, J. S. and Swager, T.M., 1998a. "Porous Shape Persistent Fluorescent Polymer Films: An Approach to TNT Sensory Materials," J. Am. Chem. Soc., 120, 5321-5322; Yang, J. S. and Swager, T.M., 1998b. "Fluorescent Porous Polymer Films as TNT Chemosensors: Electronic and Structural Effects," J. Am. Chem. Soc., 120, 11864-11873; Zhou, Q. and Swager, T., 1995. "Methodology for Enhancing the Sensitivity of Fluorescent Chemosensors: Energy Migration in Conjugated Polymers," J. Am. Chem. Soc., 117, 7017-7018.
3. Yang, J. S. and Swager, T.M., 1998a. "Porous Shape Persistent Fluorescent Polymer Films: An Approach to TNT Sensory Materials," J. Am. Chem. Soc., 120, 5321-5322; Yang, J. S. and Swager, T.M., 1998b. "Fluorescent Porous Polymer Films as TNT Chemosensors: Electronic and Structural Effects," J. Am. Chem. Soc., 120, 11864-11873; Zhou, Q. and Swager, T., 1995. "Methodology for Enhancing the Sensitivity of Fluorescent Chemosensors: Energy Migration in Conjugated Polymers," J. Am. Chem. Soc., 117, 7017-7018.
4. National Institute of Justice, 2000, "Guide for the Selection of Chemical Agent and Toxic Industrial Material Detection Equipment for Emergency First Responders," NIT Guide 100-00.
5. see www.dtic.mil/ndia/11ground/lalier.pdf
6. U.S. Army Center for Health Promotion and Preventive Medicine, 2003, "Chemical Exposure Guidelines for Deployed Military Personnel," USACHPPM Technical Guide 230, Version 1.3, Updated May, 2003.
7. U.S. Army Chemical Materials Center, "Fact Sheet: Current and Revised Chemical Warfare Agent AELs"; U.S. Army Chemical Materials Center, "Fact Sheet: Summary Information on the Army's New Guidance Policy for the Revised Airborne Exposure Limits for Chemical Warfare Agents."
8. Dagani, R., 2003. "A Better Sensor for Nerve Gas," Chemical and Engineering News, 81(10).
9. Zhang, S-W. and Swager, T., 2003. "Fluorescent Detection of Chemical Warfare Agents: Functional Group Specific Ratiometric Chemosensors," J. Am. Chem. Soc., 125(12), 3420-3421.
10. Carrano, J., 2004. "Chemical and Biological Standards Study," Defense Advanced Research and Projects Agency (available at wwwl.va.gov/ vasafety/docs/C_B_Senor_Stand_Study_Report.pdf).
11. Manginell, R. P., Frye-Mason, G. C., Schubert, W. K., Shul, R. K., and Willison, C. L., 1998. "Microfabrication of Membrane-Based Devices by Deep-Reactive Ion Etching (DRIE) of Silicon", Proc. Microstructures and Microfabricated Systems IV, Electrochemical Society, 98-14, 62-69.
12. Frye-Mason, G., Leuschen, M., la Grone, M., Wald, L., Aker, C., Dock, M., Hancock, L. F., Pagan, S., and Paul, K, 2004. "Reactive Chromophores for Sensitive and Selective Detection of Chemical Warfare Agents," SPIE Defense and Security Symposium Proceedings (in press).
13. Frye-Mason, G., Kottenstette, R., Lewis, P., Heller, E., Manginell, R., Adkins, D., Dulleck, G., Jr., Martinez, D., Sasaki, D., Mowry, C., Matzke, C., and Anderson, L., 2000. "Hand-Held Miniature Chemical Analysis System (μChemLab) for Detection of Trace Concentrations of Gas Phase Analytes," Micro Total Analysis Systems 2000, Kluwer Academic Publishers: Dordrecht, The Netherlands, 229-232.
14. Grate, J. W., Snow, A. W., Ballantine, D. S., Jr., Wohltjen, H., Abraham, M. H., McGill, R. A., and Sasson, P., 1988. Anal. Chem., 60, 869-875.