-
1
-
-
0017734907
-
The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5- benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis
-
C. H. Cashin, W. Dawson, and E. A. Kitchen. The pharmacology of benoxaprofen (2-[4-chlorophenyl]-alpha-methyl-5-benzoxazole acetic acid), LRCL 3794, a new compound with antiinflammatory activity apparently unrelated to inhibition of prostaglandin synthesis. J. Pharm. Pharmacol. 29:330-336 (1977).
-
(1977)
J. Pharm. Pharmacol.
, vol.29
, pp. 330-336
-
-
Cashin, C.H.1
Dawson, W.2
Kitchen, E.A.3
-
3
-
-
0020313042
-
Supplement to anti-inflammatory properties of benoxaprofen
-
K. Tsurumi, K. Kyuki, H. Mibu, Y. Togawa, and H. Fujimura. Supplement to anti-inflammatory properties of benoxaprofen. Oyo Yakuri 23:651-659 (1982).
-
(1982)
Oyo Yakuri
, vol.23
, pp. 651-659
-
-
Tsurumi, K.1
Kyuki, K.2
Mibu, H.3
Togawa, Y.4
Fujimura, H.5
-
4
-
-
0019948363
-
Fatal cholestatic jaundice in elderly patients taking benoxaprofen
-
A. Duthie, A. Nicholls, M. Freeth, P. Moorhead, and D. Triger. Fatal cholestatic jaundice in elderly patients taking benoxaprofen. Br. Med. J. [Clin. Rea.] 285:62 (1982).
-
(1982)
Br. Med. J. [Clin. Rea.]
, vol.285
, pp. 62
-
-
Duthie, A.1
Nicholls, A.2
Freeth, M.3
Moorhead, P.4
Triger, D.5
-
5
-
-
0020062127
-
Jaundice associated with the use of benoxaprofen
-
B. M. Goudie. G. F. Birnie, G. Watkinson, R. N. Macsween, L. H. Kissen, and N. E. Cunningham. Jaundice associated with the use of benoxaprofen. Lancet 1:959 (1982).
-
(1982)
Lancet
, vol.1
, pp. 959
-
-
Goudie, B.M.1
Birnie, G.F.2
Watkinson, G.3
Macsween, R.N.4
Kissen, L.H.5
Cunningham, N.E.6
-
6
-
-
0017800711
-
Disposition and metabolism of benoxaprofen in laboratory animals and man
-
D. H. Chatfield and J. N. Green. Disposition and metabolism of benoxaprofen in laboratory animals and man. Xenobiotica 8:133-144 (1978).
-
(1978)
Xenobiotica
, vol.8
, pp. 133-144
-
-
Chatfield, D.H.1
Green, J.N.2
-
9
-
-
0021824844
-
Absorption and disposition kinetics of flunoxaprofen and benoxaprofen in healthy volunteers
-
M. Furlanut, G. Montanari, A. Perosa, C. Velussi, A. Forgione, and P. Palatini. Absorption and disposition kinetics of flunoxaprofen and benoxaprofen in healthy volunteers. Int. J. Clin. Pharmacol. Res. 5:165-170 (1985).
-
(1985)
Int. J. Clin. Pharmacol. Res.
, vol.5
, pp. 165-170
-
-
Furlanut, M.1
Montanari, G.2
Perosa, A.3
Velussi, C.4
Forgione, A.5
Palatini, P.6
-
10
-
-
0031953577
-
Stereoselective metabolism of benoxaprofen in rats. Biliary excretion of benoxaprofen taurine conjugate and glucuronide
-
K. Mohri, K. Okada, and L. Z. Benet. Stereoselective metabolism of benoxaprofen in rats. Biliary excretion of benoxaprofen taurine conjugate and glucuronide. Drug Metab. Dispos. 26:332-337 (1998).
-
(1998)
Drug Metab. Dispos.
, vol.26
, pp. 332-337
-
-
Mohri, K.1
Okada, K.2
Benet, L.Z.3
-
11
-
-
0024554315
-
Procedures to characterize in vivo and in vitro enantioselective glucuronidation properly: Studies with benoxaprofen glucuronides
-
H. Spahn, S. Iwakawa, E. T. Lin, and L. Z. Benet. Procedures to characterize in vivo and in vitro enantioselective glucuronidation properly: studies with benoxaprofen glucuronides. Pharm. Res. 6:125-132 (1989).
-
(1989)
Pharm. Res.
, vol.6
, pp. 125-132
-
-
Spahn, H.1
Iwakawa, S.2
Lin, E.T.3
Benet, L.Z.4
-
13
-
-
0018630012
-
Stereoselective inversion of (R)-(-)-benoxaprofen to the (S)-(+)-enantiomer in humans
-
R. J. Bopp, J. F. Nash, A. S. Ridolfo, and E. R. Shepard. Stereoselective inversion of (R)-(-)-benoxaprofen to the (S)-(+)-enantiomer in humans. Drug Metab. Dispos. 7:356-359 (1979).
-
(1979)
Drug Metab. Dispos.
, vol.7
, pp. 356-359
-
-
Bopp, R.J.1
Nash, J.F.2
Ridolfo, A.S.3
Shepard, E.R.4
-
15
-
-
0023881364
-
Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs
-
F. Jamali. Pharmacokinetics of enantiomers of chiral non-steroidal anti-inflammatory drugs. Eur. J. Drug Metab. Pharmacokin. 13:1-9 (1988).
-
(1988)
Eur. J. Drug Metab. Pharmacokin.
, vol.13
, pp. 1-9
-
-
Jamali, F.1
-
16
-
-
0025990446
-
Stereoselective disposition of carprofen, flunoxaprofen, and naproxen in rats
-
S. Iwakawa, H. Spahn, L. Z. Benet, and E. T. Lin. Stereoselective disposition of carprofen, flunoxaprofen, and naproxen in rats. Drug Metab. Dispos. 19:853-857 (1991).
-
(1991)
Drug Metab. Dispos.
, vol.19
, pp. 853-857
-
-
Iwakawa, S.1
Spahn, H.2
Benet, L.Z.3
Lin, E.T.4
-
17
-
-
0021086740
-
The metabolic chiral inversion of 2-arylpropionic acids - A novel route with pharmacological consequences
-
A. J. Hutt. and J. Caldwell. The metabolic chiral inversion of 2-arylpropionic acids - a novel route with pharmacological consequences. J. Pharm. Pharmacol. 35:693-704 (1983).
-
(1983)
J. Pharm. Pharmacol.
, vol.35
, pp. 693-704
-
-
Hutt, A.J.1
Caldwell, J.2
-
18
-
-
17044445025
-
Optical isomerization mechanism of R(-)-hydratropic acid derivatives
-
Y. Nakamura, T. Yamaguchi, S. Takahashi, S. Hashimoto, K. Iwatani, and Y. Nakagawa. Optical isomerization mechanism of R(-)-hydratropic acid derivatives. J. Pharmacobiodyn. 4:18 (1981).
-
(1981)
J. Pharmacobiodyn.
, vol.4
, pp. 18
-
-
Nakamura, Y.1
Yamaguchi, T.2
Takahashi, S.3
Hashimoto, S.4
Iwatani, K.5
Nakagawa, Y.6
-
19
-
-
0028360139
-
Taurine conjugation of ibuprofen in humans and in rat liver in vitro. Relationship to metabolic chiral inversion
-
M. A. Shirley, X. Guan, D. G. Kaiser, G. W. Halstead, and T. A. Baillie. Taurine conjugation of ibuprofen in humans and in rat liver in vitro. Relationship to metabolic chiral inversion. J. Pharmacol. Exp. Ther. 269:1166-1175 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 1166-1175
-
-
Shirley, M.A.1
Guan, X.2
Kaiser, D.G.3
Halstead, G.W.4
Baillie, T.A.5
-
20
-
-
0028872018
-
Stereospecific taurine conjugation of the trans-OH metabolite (active metabolite) of CS-670, a new 2-arylpropionic acid nonsteroidal anti-inflammatory drug, in dogs
-
M. Asami, W. Takasaki, H. Iwabuchi, H. Haruyama, K. Wachi, A. Terada, and Y. Tanaka. Stereospecific taurine conjugation of the trans-OH metabolite (active metabolite) of CS-670, a new 2-arylpropionic acid nonsteroidal anti-inflammatory drug, in dogs. Biol. Pharm. Bull. 18:1584-1589 (1995).
-
(1995)
Biol. Pharm. Bull.
, vol.18
, pp. 1584-1589
-
-
Asami, M.1
Takasaki, W.2
Iwabuchi, H.3
Haruyama, H.4
Wachi, K.5
Terada, A.6
Tanaka, Y.7
-
21
-
-
0010471382
-
Relation between optical isomerism and taurine conjugation of phenylpropionic acid derivatives
-
S. Kitamura, T. Yoshimura, K. Sugihara, K. Tatsumi, T. Konishi, and H. Nishikawa. Relation between optical isomerism and taurine conjugation of phenylpropionic acid derivatives. Xenobio. Metabol. and Dispos. 11:s74-s75 (1996).
-
(1996)
Xenobio. Metabol. and Dispos.
, vol.11
-
-
Kitamura, S.1
Yoshimura, T.2
Sugihara, K.3
Tatsumi, K.4
Konishi, T.5
Nishikawa, H.6
-
22
-
-
0345561583
-
In vivo studies on chiral inversion and amino acid conjugation of 2-[4-(3-methyl-2-thienyl)phenyl]propionic acid in rats and dogs
-
T. Konishi, H. Nishikawa, S. Kitamura, and K. Tatsumi. In vivo studies on chiral inversion and amino acid conjugation of 2-[4-(3-methyl-2-thienyl)phenyl] propionic acid in rats and dogs. Drug Metab. Dispos. 27:158-160 (1999).
-
(1999)
Drug Metab. Dispos.
, vol.27
, pp. 158-160
-
-
Konishi, T.1
Nishikawa, H.2
Kitamura, S.3
Tatsumi, K.4
-
23
-
-
0026782199
-
Formation of glycin conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dogs
-
Y. Tanaka, Y. Shimomura, T. Hirota, A. Nozaki, M. Ebata, W. Takasaki, E. Shigehara, R. Hayashi, and J. Caldwell. Formation of glycin conjugate and (-)-(R)-enantiomer from (+)-(S)-2-phenylpropionic acid suggesting the formation of the CoA thioester intermediate of (+)-(S)-enantiomer in dogs. Chirality 4:342-348 (1992).
-
(1992)
Chirality
, vol.4
, pp. 342-348
-
-
Tanaka, Y.1
Shimomura, Y.2
Hirota, T.3
Nozaki, A.4
Ebata, M.5
Takasaki, W.6
Shigehara, E.7
Hayashi, R.8
Caldwell, J.9
-
24
-
-
0017842362
-
A Radiochemical Assay for glycine N-acyltransferase activity. Some properties of the enzyme in rat and rabbit
-
M. O. James and J. R. Bend. A Radiochemical Assay for glycine N-acyltransferase activity. Some properties of the enzyme in rat and rabbit. Biochem. J. 172:285-291 (1978).
-
(1978)
Biochem. J.
, vol.172
, pp. 285-291
-
-
James, M.O.1
Bend, J.R.2
|