The Brucella abortus Cu,Zn superoxide dismutase is required for optimal resistance to oxidative killing by murine macrophages and wild-type virulence in experimentally infected mice

Infection and Immunity

Volumn 73, Issue 5, 2005, Pages 2873-2880

  Gee, Jason M ^a,b   Valderas, Michelle Wright ^a,d   Kovach, Michael E ^b,e   Grippe, Vanessa K ^b,f   Robertson, Gregory T ^c,g   Ng, Wai Leung ^c,h   Richardson, John M ^c   Winkler, Malcolm E ^c,h   Roop II, R Martin ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d OKLAHOMA STATE UNIVERSITY   (United States)

^e BALDWIN WALLACE COLLEGE   (United States)

^f CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^g Cumbre Inc   (United States)

^h INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOCYNIN; COPPER; COPPER ZINC SUPEROXIDE DISMUTASE; HOST FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; OXYGEN; PYROGALLOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RNA BINDING PROTEIN; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BACTERIAL INFECTION; BACTERIAL STRAIN; BRUCELLA ABORTUS; CELL CULTURE; CELL KILLING; CELL LYSATE; CONTROLLED STUDY; ENZYME MECHANISM; FEMALE; HOST CELL; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TWO DIMENSIONAL GEL ELECTROPHORESIS; VIRULENCE; WILD TYPE;

ANIMALS; BRUCELLA ABORTUS; BRUCELLOSIS; CELLS, CULTURED; FEMALE; GENE EXPRESSION REGULATION, BACTERIAL; HOST FACTOR 1 PROTEIN; HUMANS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MUTATION; RESPIRATORY BURST; SUPEROXIDE DISMUTASE; VIRULENCE;

EID: 17644362734     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.5.2873-2880.2005     Document Type: Article

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