Age-dependence of free radical-induced oxidative damage in ischemic-reperfused rat heart

Archives of Gerontology and Geriatrics

Volumn 22, Issue 3, 1996, Pages 297-309

  Nagy, Katalin ^a   Takács, Ildikó E ^b   Pankucsi, Csaba ^b  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Ascorbyl radical; Centrophenoxine; ESR spectroscopy; Heart ischemia reperfusion; Peroxidative damage; Protein oxidation

Indexed keywords

ASCORBIC ACID; CARBONYL DERIVATIVE; FREE RADICAL; MECLOFENOXATE; PROTEIN; SCAVENGER;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; MALE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALIA;

EID: 17444439496     PISSN: 01674943     EISSN: None     Source Type: Journal    
DOI: 10.1016/0167-4943(96)00700-5     Document Type: Article

References (31)

1. Arroyo, C.M., Kramer, J.H., Dickens, B.F. and Weglicki, W.B. (1987): Identification of free radicals in myocardial ischemia/reperfusion by spin trapping with nitrone DMPO. FEBS Lett., 221, 101-104.
2. Buettner, G.R. and Jurkiewicz, B.A. (1993): Ascorbate free radical as a marker of oxidative stress: an EPR study. Free Radic. Biol. Med., 14, 49-55.
3. Carney, J.M., Starke-Reed, P.E., Oliver, C.N., Landum, R.W., Cheng, M.S., Wu, F.F. and Floyd, R.A. (1991): Reversal of age-related increase in brain protein oxidation, decrease in enzyme activity and loss in temporal and spatial memory by chronic administration of the spin-trapping compound N-tert-butyl-α-phenyl-nitrone. Proc. Natl. Acad. Sci. USA, 88, 3633-3636.
4. Cutler, R.G. (1984): Antioxidants, aging and longevity. In: Free Radicals in Biology, Vol. VI, pp. 371-428. Editor: W.A. Pryor. Academic Press Inc., New York.
5. Garland, D., Russell, P. and Zigler, J.S. (1988): The oxidative modification of lens proteins. In: Basic Life Sciences, pp. 347-353. Editors: M.G. Simic, K.S. Taylor, J.F. Ward and C. von Sonntag. Plenum Press, New York.
6. Langendorff, O. (1895): Untersuchungen am überlebenden Säugetierherzen. Pflügers Arch., 61, 291-332 (in German).
7. Levine, R.L., Garland, D., Oliver, C.N., Amici, A., Climent, I., Lenz, A-G., Ahn, B-W., Shaltiel, S. and Stadtman, E.R. (1990): Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol., 186, 464-478.
8. Mao, G.D., Thomas, P.D., Lopaschuk, G.D. and Poznansky, M.J. (1993): Superoxide dismutase (SOD) - catalase conjugates. Role of hydrogen peroxide and the Fenton reaction in SOD toxicity. J. Biol. Chem., 268, 416-420.
9. Markwell, M.A.K., Haas, S.M., Bieber, L.L. and Tolbert, N.E. (1978): A modification of Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem., 87, 206-210.
10. Nagy, K. and Zs.-Nagy, I. (1984): Alterations in the molecular weight distribution of proteins in rat brain synaptosomes during aging and centrophenoxine treatment of old rats. Mech. Ageing Dev., 28, 171-176.
11. Nagy, K., Dajkó, G., Uray, I. and Zs.-Nagy, I. (1994): Comparative studies on the free radical scavenger properties of two nootropic drugs, CPH and BCE-001. Ann. N.Y. Acad. Sci., 717, 115-121.
12. Nohl, H., Stolze, K., Napetschnig, S. and Ishikawa, T. (1991): Is oxidative stress primarily involved in reperfusion injury of the ischemic heart? Free Radic. Biol. Med., 11, 581-588.
13. Oliver, C.N., Ahn, B-W., Moerman, E.J., Goldstein, S. and Stadtman, E.R. (1987): Age-related changes in oxidized proteins. J. Biol. Chem., 262, 5488-5491.
14. Oliver, C.N., Starke-Reed, P.E., Stadtman, E.R., Liu, G.J., Carney, J.M. and Floyd, R.A. (1990): Oxidative damage to brain proteins, loss of glutamine synthetase activity and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proc. Natl. Acad. Sci. USA, 87, 5144-5147.
15. Omar, B., McCord, J. and Downey, J. (1991): Ischemia-reperfusion. In: Oxidative Stress: Oxidants and Antioxidants, pp. 493-527. Editor: H. Sies. Academic Press.
16. Pietri, S., Culcasi, M. and Cozzone, P.J. (1989): Real-time continuous-flow spin trapping of hydroxyl free radical in the ischemic and post-ischemic myocardium. Eur. J. Biochem., 186, 163-173.
17. Pietri, S., Culcasi, M., Stella, L. and Cozzone, P.J. (1990): Ascorbyl free radical as a reliable indicator of free radical-mediated myocardial ischemic and post-ischemic injury. Eur. J. Biochem., 193, 845-854.
18. Poston, J.M. and Parenteau, G.L. (1992): Biochemical effects of ischemia on isolated, perfused rat heart tissues. Arch. Biochem. Biophys., 295, 34-41.
19. Powell, S.R. and Tortolani, A.J. (1992): Recent advances in the role of reactive oxygen intermediates in ischemic injury. J. Surg. Res., 53, 417-429.
20. Roy, D., Pathak, D.N. and Singh, R. (1983): Effect of centrophenoxine on the antioxidative enzymes in various regions of the aging rat brain. Exp. Geront., 18, 185-197.
21. Simpson, P.J. and Lucchesi, B.R. (1987): Free radicals and myocardial ischemia and reperfusion injury. J. Lab. Clin. Med., 110, 13-30.
22. Spoerri, P.E., Glees, P. and El-Ghazzawi, E. (1974): Accumulation of lipofuscin in the myocardium of senile guinea pigs: dissolution and removal of lipofuscin following dimethylaminoethyl-p-chlorophenoxy-acetate administration: an electron microscope study. Mech. Ageing Dev., 3, 311-321.
23. Starke-Reed, P.E. and Oliver, C.N. (1989): Protein oxidation and proteolysis during aging and oxidative stress. Arch. Biochem. Biophys., 275, 559-567.
24. Sun, J-Z., Kaur, H., Halliwell, B., Li, X-Y. and Bolli, R. (1993): Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo: direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning. Circ. Res., 73, 534-549.
25. Takács, I.E., Pankucsi, Cs., Varga, Sz.I. and Matkovics, B. (1993): Changes in antioxidant defence of Langendorff rat hearts during ischemia and reperfusion. In: Oxygen Free Radicals and Scavengers in the Natural Sciences, pp. 281-284. Editors: Gy. Mózsik, I. Emerit, J. Fehér, B. Matkovics and Á. Vincze. Akadémiai Kiadó, Budapest.
26. Tavazzi, B., Lazzarino, G., DiPierro, D. and Giardina, B. (1992): Malondialdehyde production and ascorbate decrease are associated to the reperfusion of the isolated post-ischemic rat heart. Free Radic. Biol. Med., 13, 75-78.
27. Tosaki, A., Droy-Lefaix, M.T., Pali, T. and Das, D.K. (1993): Effects of SOD, catalase, and a novel antiarrhytmic drug, EGB 761, on reperfusion-induced arrhythmias in isolated rat hearts. Free Radic. Biol. Med., 14, 361-370.
28. Wang, X., Liu, J., Yokoi, I., Kohno, M. and Mori, A. (1992): Direct detection of circulating free radicals in the rat using electron spin resonance spectrometry. Free Radic. Biol. Med., 12, 121-126.
29. . free radical scavenger. In: CRC Handbook of Free Radicals and Antioxidants in Biomedicine, Vol. II., pp. 87-94. Editor: J. Miquel. CRC Press Inc., Boca Raton, Florida.
30. Zs.-Nagy, I. (1994): The Membrane Hypothesis of Aging. CRC Press Inc., Boca Raton, Florida.
31. Zs.-Nagy, I. and Floyd, R.A. (1984): Electron spin resonance spectroscopic demonstration of the hydroxyl free radical scavenger properties of dimethylaminoethanol in spin trapping experiments confirming the molecular basis for the biological effects of centrophenoxine. Arch. Gerontol. Geriatr., 3, 297-310.