Interleukin-10 suppresses IP-10 gene transcription by inhibiting the production of class I interferon

Blood

Volumn 92, Issue 12, 1998, Pages 4742-4749

  Tebo, Julie M ^a   Kim, Hee Sun ^a   Gao, Jing ^a   Armstrong, David A ^a   Hamilton, Thomas A ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; CHEMOKINE; CYCLOHEXIMIDE; GAMMA INTERFERON; INTERLEUKIN 10; MESSENGER RNA; RANTES;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSCRIPTION; INTERFERON PRODUCTION; MESSENGER RNA SYNTHESIS; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL;

EID: 17444418985     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.12.4742.424k26_4742_4749     Document Type: Article

References (15)

1. Adams DO, Hamilton TA: The cell biology of macrophage activation [review]. Annu Rev Immunol 2:283, 1984
2. Adams DO, Hamilton TA: Macrophages as destructive cells in host defense, in Gallin JI, Goldstein IM, Snyderman R (eds): Inflammation: Basic Principles and Clinical Correlates. New York, NY, Raven, 1992, p 637
3. Nathan CF, Cohn ZA: Cellular components of inflammation: Monocytes and macrophages, in Kelly W, Harris E, Ruddy S, Hedge R (eds): Textbook of Rheumatology. Philadelphia, PA, Saunders, 1995, p 144
4. Bogdan C, Vodovotz Y, Nathan C: Macrophage deactivation by interleukin 10. J Exp Med 174:1549, 1991
5. Moore KW, O'Garra A, De Waal Malefyt R, Vieira P, Mosmann TR: interleukin-10. Annu Rev Immunol 11:165, 1993
6. Ho AS, Moore KW: Interleukin-10 and its receptor. Ther Immunol 1:173, 1994
7. Fiorentino DF, Zlotnik A, Mosmann TR, Howard M, O'Garra A: IL-10 inhibits cytokine production by activated macrophages. J Immunol 11:3815, 1991
8. Ohmori Y, Hamilton TA: Regulation of macrophage gene expression by T cell derived lymphokines. Pharmacol Ther 63:235, 1994
9. Bogdan C, Paik J, Vodovotz Y, Nathan C: Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-β and interleukin-10. J Biol Chem 267:23301, 1992
10. Wang P, Wu P, Siegel MI, Egan RW, Billah MM: IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol 153:811, 1994
11. Kasama T, Strieter RM, Lukacs NW, Burdick MD, Kunkel SL: Regulation of neutrophil-derived chemokine expression by IL-10. J Immunol 152:3559, 1994
12. Shrikant P, Weber E, Jilling T, Benveniste EN: Intercellular adhesion molecule-l gene expression by glial cells. Differential mechanisms of inhibition by IL-10 and IL-6. J Immunol 155:1489, 1995
13. Seitz M, Loetscher P, Dewald B, Towbin H, Gallati H, Baggiolini M: Interleukin-10 differentially regulates cytokine inhibitor and chemokine release from blood mononuclear cells and fibroblasts. Eur J Immunol 25:1129, 1995
14. Berkman N, John M, Roesems G, Jose PJ, Barnes PJ, Chung KF: Inhibition of macrophage inflammatory protein-lα expression by IL-10. Differential sensitivities in human blood monocytes and alveolar macrophages. J Immunol 155:4412, 1995
15. Takeshita S, Gage JR, Kishimoto T, Vredevoe DL, MartínezMaza O: Differential regulation of IL-6 gene transcription and expression by IL-4 and IL-10 in human monocytic cell lines. J Immunol 156:2591, 1996