Inhibition of gap junction currents by the abused solvent toluene

Drug and Alcohol Dependence

Volumn 78, Issue 2, 2005, Pages 221-224

  Del Re, Angelo M ^a   Woodward, John J ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Connexin; Electrophysiology; HEK 293

Indexed keywords

CELL MEMBRANE PROTEIN; GAP JUNCTION PROTEIN; ORGANIC SOLVENT; THINNER; TOLUENE;

ARTICLE; CELL COMMUNICATION; CHANNEL GATING; CONCENTRATION PROCESS; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOCHEMISTRY; CYTOPATHOLOGY; DRUG ABUSE; ELECTRIC CONDUCTIVITY; ELECTROPHYSIOLOGY; EMBRYO; GAP JUNCTION; HUMAN; HUMAN CELL; INHALATION; INHIBITION KINETICS; INTOXICATION; LONG TERM EXPOSURE; MEMBRANE CURRENT; METABOLIC INHIBITION; MOLECULAR BIOLOGY; MOLECULAR WEIGHT; MOOD DISORDER; PATCH CLAMP; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TOXICOKINETICS;

EID: 17444418335     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2004.10.005     Document Type: Article

References (23)

1. A.S. Bale, C.T. Smothers, and J.J. Woodward Inhibition of neuronal nicotinic acetylcholine receptors by the abused solvent, toluene Br. J. Pharmacol. 137 2002 375 383
2. M.J. Beckstead, J.L. Weiner, E.I. Eger 2nd, D.H. Gong, and S.J. Mihic Glycine and γ-aminobutyric acid (A) receptor function is enhanced by inhaled drugs of abuse Mol. Pharmacol. 57 2000 1199 1205
3. T. Blevins, T. Mirshahi, L.J. Chandler, and J.J. Woodward Effects of acute and chronic ethanol exposure on heteromeric N-methyl-d-aspartate receptors expressed in HEK 293 cells J. Neurochem. 69 1997 2345 2354
4. V.P. Bozhkova The specificity of gap junctional channels in early fish embryos and its significance for pattern formation in development Membr. Cell Biol. 11 1998 803 815
5. M. Burry, M. Guizzetti, J. Oberdoerster, and L.G. Costa Developmental neurotoxicity of toluene: in vivo and in vitro effects on astroglial cells Dev. Neurosci. 25 2003 14 19
6. J.M. Burt, and D.C. Spray Volatile anesthetics block intercellular communication between neonatal rat myocardial cells Circ. Res. 65 1989 829 837
7. A. Butterweck, U. Gergs, C. Elfgang, K. Willecke, and O. Traub Immunochemical characterization of the gap junction protein connexin-45 in mouse kidney and transfected human HeLa cells J. Membr. Biol. 141 1994 247 256
8. S.L. Cruz, M. Tooraj, B. Thomas, R.L. Balster, and J.J. Woodward Effects of the abused solvent toluene on recombinant N-methyl-d-aspartate and non-N-methyl-d-aspartate receptors expressed in Xenopus oocytes J. Pharmacol. Exp. Ther. 286 1998 334 340
9. S.L. Cruz, R.L. Balster, and J.J. Woodward Effects of volatile solvents on recombinant N-methyl-d-aspartate receptors expressed in Xenopus oocytes Br. J. Pharmacol. 131 2000 1303 1308
10. S.L. Cruz, G. Orta-Salazar, M.Y. Gathereau, Millan-Perez, L. Pena, and E.M. Salinas-Stefanon Inhibition of cardiac sodium currents by toluene exposure Br. J. Pharmacol. 140 2003 653 660
11. 2+ oscillations in pancreatic acini by multiple mechanisms Am. J. Physiol. 269 1995 G779 G788
12. S. Eskandari, G.A. Zampighi, D.W. Leung, E.M. Wright, and D.D. Loo Inhibition of gap junction hemichannels by chloride channel blockers J. Membr. Biol. 185 2002 93 102
13. E.G.A. Harks, J.P. Camina, P.H.J. Peters, D.L. Ypey, W.J.J.M. Scheenen, E.J.J. von Zoelen, and A.P.R. Theuvenet Besides affecting intracellular calcium signaling, 2-APB reversibly blocks gap junctional coupling in confluent monolayers, thereby allowing the measurement of single-cell membrane currents in undissociated cells FASEB J. 2003 10.1096/fj. 02-0786fje
14. G.F. Lopreato, R. Phelan, C.M. Borghese, M.J. Beckstead, and S.J. Mihic Inhaled drugs of abuse enhance serotonin-3 receptor function Drug Alcohol Depend. 70 2003 11 15
15. L. Miquerol, L. Dupays, M. Theveniau-Ruissy, S. Alcolea, T. Jarry-Guichard, P. Abran, and D. Gros Gap junctional connexins in the developing mouse cardiac conduction system Novartis Found. Symp. 250 2003 80 98
16. 2+ signalling pathway in cultured rabbit gastric epithelial cells J. Gastroenterol. 39 2004 104 110
17. C.R. Rose, and B.R. Ransom Gap junctions equalize intracellular Na+ concentration in astrocytes Glia 20 1997 299 307
18. R. Rozental, A.F. Andrade-Rozenta, X. Zheng, M. Urban, D.C. Spray, and F.C. Chiu Gap junction-mediated bidirectional signaling between human fetal hippocampal neurons and astrocytes Dev. Neurosci. 23 2001 420 431
19. J.C. Sáez, V.M. Berthoud, M.C. Brañes, A.D. Martínez, and E.C. Beyer Plasma membrane channels formed by connexins: their regulation and functions Physiol. Rev. 83 2003 1359 1400
20. I. Simpson, B. Rose, and W.R. Loewenstein Size limit of molecules permeating the junctional membrane channels Science 195 1977 294 296
21. C.H. Steffee, G.J. Davis, and K.K. Nicol A whiff of death: fatal volatile solvent inhalation abuse South. Med. J. 89 1996 879 884
22. R. Tillar, T.J. Shafer, and J.J. Woodward Toluene inhibits voltage-sensitive calcium channels expressed in pheochromocytoma cells Neurochem. Int. 41 2002 391 397
23. J.J. Woodward, M. Nowak, and D.L. Davies Effects of the abused solvent toluene on recombinant P2X receptors expressed in HEK293 cells Brain Res. Mol. Brain Res. 125 2004 86 95