Suplatast tosilate dimethylsulfonium treatment for steroid-dependent nephrotic syndrome

Pediatrics International

Volumn 47, Issue 2, 2005, Pages 230-231

  Ohtomo, Yoshiyuki ^a,b   Fujinaga, Shu Ichiro ^a,b   Hattori, Motoshi ^c  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Antiallergic drug; Nephrotic syndrome; Steroid responsive; Th2 cytokines

Indexed keywords

ANTIALLERGIC AGENT; CROMOGLYCATE DISODIUM; CYCLOPHOSPHAMIDE; PREDNISOLONE; STEROID; SUPLATAST TOSYLATE;

ADOLESCENT; ADULT; ALLERGIC DISEASE; ARTICLE; ASTHMA; ATOPIC DERMATITIS; CLINICAL ARTICLE; DISEASE ASSOCIATION; DRUG EFFICACY; DRUG MECHANISM; HUMAN; MALE; NEPHROTIC SYNDROME; PRIORITY JOURNAL; SCHOOL CHILD; STEROID THERAPY; TH2 CELL;

ADOLESCENT; ADULT; ANTI-ALLERGIC AGENTS; ARYLSULFONATES; CHILD; FEMALE; GLUCOCORTICOIDS; HUMANS; MALE; NEPHROSIS, LIPOID; PILOT PROJECTS; PREDNISOLONE; SULFONIUM COMPOUNDS;

EID: 17444401267     PISSN: 13288067     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1442-200x.2005.02040.x     Document Type: Article

References (9)

1. Meadow SR, Sarsfield JK. Steroid-responsive and nephrotic syndrome and allergy: clinical studies. Arch. Dis. Child. 1981; 56: 509-16.
2. Wardle EN. Minimal change nephrosis and allergy. Nephron 1996; 74: 422-3.
3. Mathieson PW. Immune dysregulation in minimal change nephropathy. Nephrol. Dial. Transplant. 2003; 18 (Suppl. 6): vi26-9.
4. Holdsworth SR, Kitching AR, Tipping PG. Th1 and Th2 T helper cell subsets affect patterns of injury and outcomes in glomerulonephritis. Kidney Int. 1999; 55: 1198-216.
5. Holgate ST. Asthma: past, present and future. Eur. Respir. J. 1993; 6: 1507-20.
6. Koda A, Yanagihara Y, Matsuura N. IPD-1151T: a prototype drug of IgE antibody synthesis modulation. Agents Actions Suppl. 1991; 34: 369-78.
7. Yanagihara Y, Kiniwa M, Ikizawa K, Sida T, Matsuura N, Koda A. Suppression of IgE production by IPD-1151T (suplatast tosilate), a new dimethylsulfonium agent: (2) Regulation of Ige response. Jpn. J. Pharmacol. 1993; 61: 31-9.
8. Yamaya H, Basaki Y, Togawa M, Kojima M, Kiniwa M, Matsuura N. Down-regulation of Th2 cell-mediated murine peritoneal eosinophilia by antiallergic agents. Life Sci. 1995; 19: 1647-54.
9. Tamaoki J, Kondo M, Sakai N et al. Effect of suplatast tosilate, a Th2 cytokine inhibitor, on steroid-dependent asthma: a double-blind randomised study. Lancet 2000; 356: 273-8.