Biopreservation of red blood cells: Past, present, and future

Transfusion Medicine Reviews

Volumn 19, Issue 2, 2005, Pages 127-142

  Scott, Kirby L ^a   Lecak, Jelena ^a   Acker, Jason P ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN;

BLOOD STORAGE; CELL FUNCTION; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; COLD INJURY; COOLING; CRYOPRESERVATION; CRYOPROTECTION; DESICCATION; ERYTHROCYTE; FREEZE DRYING; FREEZING; HUMAN; PRESERVATION; QUALITY CONTROL; REVIEW; RISK ASSESSMENT; TECHNIQUE; VITRIFICATION;

EID: 17444392867     PISSN: 08877963     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tmrv.2004.11.004     Document Type: Article

References (169)

1. M. Schwabbauer Normal erythrocyte production, physiology and destruction E.A. Stiene-Martin C.A. Lotspeich-Steininger J.A. Koepke Clinical hematology: Principles, procedures and correlations 1998 Lippincott Philadelphia 57 72
2. N. Mohandas, and J.A. Chasis Red blood cell deformability, membrane material properties and shape: Regulation by transmembrane, skeletal and cytosolic proteins and lipids Semin. Hematol. 30 1993 171 192
3. L.H. Derick, S.C. Liu, and A.H. Chishti Protein immunolocalization in the spread erythrocyte membrane skeleton Eur. J. Cell Biol. 57 1992 317 320
4. S.P. Klinken Red blood cells Int. J. Biochem. Cell Biol. 34 2002 1513 1518
5. D. Bratosin, J. Estaquier, and J.C. Ameisen Molecular and cellular mechanisms of erythrocyte programmed cell death: Impact on blood transfusion Vox Sang. 83 2002 307 310
6. A. Hustin Note sur une nouvelle méthode de transfusion Annales et Bulletin des Séances: Société des Sciences Médicales et Naturelles de Bruxelles 72 1914 104 111
7. P. Rous, and J.R. Turner The preservation of living red blood cells in vitro. I. Methods of preservation J. Exp. Med. 23 1916 219 237
8. P. Rous, and J.R. Turner The preservation of living red blood cells in vitro II. The transfusion of kept cells J. Exp. Med. 23 1916 239 248
9. P.L. Mollison The introduction of citrate as an anticoagulant for transfusion and of glucose as a red cell preservative Br. J. Haematol. 108 2000 13 18
10. P. Douzou Cryobiochemistry: An introduction 1977 Academic Press New York 1 286
11. M.J. Taylor Physico-chemical principles in low temperature biology B.W.W. Grout G.J. Morris The effects of low temperatures on biological systems 1987 Edward Arnold Ltd London 3 71
12. C. Bishop Some in vitro effects of adenine added to stored blood Transfusion 4 1964 265 270
13. G.J. Brewer, and R.D. Powell The adenosine triphosphate content of glucose-6-phosphate dehydrogenase-deficient and normal erythrocytes, including studies of a glucose-6-phosphate dehydrogenase-deficient man with "elevated erythrocytic ATP" J. Lab. Clin. Med. 67 1966 726 740
14. A.R. Haradin, R.I. Weed, and C.F. Reed Changes in physical properties of stored erythrocytes: Relationship to survival in vivo Transfusion 9 1969 229 237
15. R.T. Card Red cell membrane changes during storage Transfus. Med. Rev. 2 1988 40 47
16. J.R. Hess, and T.J. Greenwalt Storage of red blood cells: New approaches Transfus. Med. Rev. 16 2002 283 295
17. C.R. Valeri, and F.B. Collins Physiologic effects of 2,3-DPG-depleted red cells with high affinity for oxygen J. Appl. Physiol. 31 1971 823 827
18. E. Beutler Back to the future in RBC preservation Transfusion 40 2000 983 985
19. S.L. Fridey Standards for blood banks and transfusion services 2003 American Association of Blood Banks Bethesda, MD 161 163
20. G.L. Moore Additive solutions for better blood preservation CRC. Crit. Rev. Clin. Lab. Sci. 25 1987 211 229
21. D.M. Harmening Modern blood banking and transfusion practices 1999 F.A. Davis Company Philadelphia, PA 9 11
22. C.F. Högman Preparation and preservation of red cells Vox Sang. 74 1998 177 187
23. C.F. Högman Liquid-stored red blood cells for transfusion: A status report Vox Sang. 76 1999 67 77
24. E. Beutler Preservation of liquid red cells E.C. Rossi T.L. Simon G.S. Moss Principles of transfusion medicine 1991 Williams & Wilkins Baltimore 47 56
25. C.F. Högman, and H.T. Meryman Storage parameters affecting red blood cell survival and function after transfusion Transfus. Med. Rev. 13 1999 275 296
26. C.M. Martin, W.J. Sibbald, and X. Lu Age of transfused red blood cells is associated with ICU length of stay Clin. Invest. Med. 17 1994 B21
27. P.E. Marik, and W.J. Sibbald Effect of stored-blood transfusion on oxygen delivery in patients with sepsis JAMA 269 1993 3024 3029
28. M.A. Blajchman Immunomodulation and blood transfusion Am. J. Ther. 9 2002 389 395
29. S.R. Leal-Noval, I. Jara-Lopez, and J.L. Garcia-Garmndia Influence of erythrocyte concentrate storage time on post-surgical morbidity in cardiac surgery patients Anesthesiology 98 2003 815 822
30. G. Zallen, P.J. Offner, and E.E. Moore Age of transfused red blood cells is an independent risk factor for postinjury multiple organ failure Am. J. Surg. 178 1999 570 572
31. E.C. Vamvakas, and H.F. Taswell Long-term survival after blood transfusion Transfusion 34 1994 471 477
32. G.S. Whyte The transfused population of Canterbury, New Zealand and its mortality Vox Sang. 54 1988 65 70
33. F.R. Purdy, M.G. Tweeddale, and P.M. Marrick Association of mortality with age of blood transfused in septic ICU patients Can. J. Anaesth. 44 1997 1256 1261
34. J. Ho, W.J. Sibbald, and I.H. Chin-Yee Effects of storage on efficacy of red cell transfusion: When is it not safe? Crit. Care Med. 31 2003 S687 S697
35. D. Bratosin, J. Estaquier, and J.C. Ameisen Molecular and cellular mechanisms of erythrocyte programmed cell death: Impact on blood transfusion Vox Sang. 83 2002 307 310 (suppl. 1)
36. W.H. Walker, M. Netz, and K.H. Ganshirt 49 day storage of erythrocyte concentrates in blood bags with the PAGGS-mannitol Beitr. Infusionsther. 26 1990 55 59
37. C.R. Valeri, L.E. Pivacek, and G.P. Cassidy The survival, function and hemolysis of human RBCs stored at 4°C in additive solution (AS-1, AS-3 or AS-5) for 42 days and then biochemically modified, frozen, thawed, washed and stored at 4°C in sodium chloride and glucose solution for 24 hours Transfusion 40 2000 1341 1345
38. N. Hamasaki, and M. Yamamoto Red blood cell function and blood storage Vox Sang. 79 2000 191 197
39. C.R. Valeri Status report on the quality of liquid and frozen red blood cells Vox Sang. 83 2002 193 196
40. P. Mazur Basic problems in cryobiology K.D. Timmerhaus Advances in cryogenic engineering vol. 9 1964 Plenum Press New York 28 37
41. J. Lecak, K. Scott, and C. Young Evaluation of red blood cells stored at -80°C in excess of 10 years Transfusion 44 2004 1306 1313
42. C.R. Valeri, G. Ragno, and L.E. Pivacek An experiment with glycerol-frozen red blood cells stored at -80°C for up to 37 years Vox Sang. 79 2000 168 174
43. P. Mazur, S.P. Leibo, and E.H.Y. Chu A two-factor hypothesis of freezing injury: Evidence from Chinese hamster tissue-culture cells Exp. Cell Res. 71 1972 345 355
44. H.T. Meryman The exceeding of a minimum tolerable cell volume in hypertonic suspension as a cause of freezing injury G.E. Wolstenholme M. O'Connor The frozen cell 1970 Churchill London 51 64
45. A.M.M. Zade-Oppen Posthypertonic hemolysis in sodium chloride systems Acta Physiol. Scand. 73 1968 341 364
46. D.E. Pegg, and M.P. Diaper The effect of initial tonicity on freeze/thaw injury to human red cells suspended in solutions of sodium chloride Cryobiology 28 1991 18 35
47. D.E. Pegg, and M.P. Diaper On the mechanism of injury to slowly frozen erythrocytes Biophys. J. 54 1988 471 488
48. J.E. Lovelock The denaturation of lipid-protein complexes as a cause of damage by freezing Proc. R. Soc. Lond. B 147 1957 427 434
49. J.E. Lovelock The haemolysis of human red blood cells by freezing and thawing Biochim. Biophys. Acta 10 1953 414 426
50. P. Mazur, and K.W. Cole Influence of cell concentration on the contribution of unfrozen fraction and salt concentration to the survival of slowly frozen human erythrocytes Cryobiology 22 1985 509 536
51. P. Mazur, and N. Rigopoulos Contributions of unfrozen fraction and of salt concentration to the survival of slowly frozen human erythrocytes: Influence of warming rate Cryobiology 20 1983 274 289
52. P. Mazur, W.F. Rall, and N. Rigopoulos Relative contributions of the fraction of unfrozen water and of salt concentration to the survival of slowly frozen human erythrocytes Biophys. J. 36 1981 653 675
53. D.E. Pegg, and M.P. Diaper The "unfrozen fraction" hypothesis of freezing injury to human erythrocytes: A critical examination of the evidence Cryobiology 26 1989 30 43
54. H.T. Meryman Modified model for the mechanism of freezing injury in erythrocytes Nature 218 1968 333 336
55. H.T. Meryman Osmotic stress as a mechanism of freezing injury Cryobiology 8 1971 489 500
56. H.T. Meryman Freezing injury and its prevention in living cells Annu. Rev. Biophys. 3 1974 341 363
57. H. Ishiguro, and B. Rubinsky Mechanical interactions between ice crystals and red blood cells during directional solidification Cryobiology 31 1994 483 500
58. T. Nei Mechanism of freezing injury to erythrocytes: Effect of initial cell concentration on the post-thaw hemolysis Cryobiology 18 1981 229 237
59. D.E. Pegg The effect of cell concentration on the recovery of human erythrocytes after freezing and thawing in the presence of glycerol Cryobiology 18 1981 221 228
60. P. Mazur Kinetics of water loss from cells at subzero temperatures and the likelihood of intracellular freezing J. Gen. Physiol. 47 1963 347 369
61. J.O.M. Karlsson, E.G. Cravalho, and M. Toner Intracellular ice formation: Causes and consequences Cryo Letters 14 1993 323 334
62. P. Mazur Freezing of living cells: Mechanisms and implications Am. J. Physiol. 247 1984 C125 C142
63. M. Toner Nucleation of ice crystals inside biological cells P.L. Steponkus Advances in low temperature biology vol. 2 1993 JAI Press Ltd London 1 51
64. K. Muldrew, and L.E. McGann Mechanisms of intracellular ice formation Biophys. J. 57 1990 525 532
65. K. Muldrew, J.P. Acker, and J.A.W. Elliott The water to ice transition: Implications for living cells B.J. Fuller N. Lane E.E. Benson Life in the frozen state 2004 CRC Press New York 67 108
66. J.P. Acker, and L.E. McGann Innocuous intracellular ice improves survival of frozen cells Cell Transplant. 11 2002 563 571
67. R. Fowler, and M. Toner Prevention of hemolysis in rapidly frozen erythrocytes by using a laser pulse Ann. N. Y. Acad. Sci. 858 1998 245 252
68. B. Luyet, and G. Rapatz A review of basic researches on the cryopreservation of red blood cells Cryobiology 6 1970 425 482
69. M.W. Scheiwe, H.E. Nick, and C. Körber An experimental study on the freezing of red blood cells with and without hydroxyethyl starch Cryobiology 19 1982 461 477
70. G. Rapatz, J.J. Sullivan, and B.J. Luyet Preservation of erythrocytes in blood containing various cryoprotective agents, frozen at various rates and brought to a given final temperature Cryobiology 5 1968 18 25
71. K.R. Diller Intracellular freezing: Effect of extracellular supercooling Cryobiology 12 1975 480 485
72. J.O.M. Karlsson, E.G. Cravalho, and I.H.M. Borel Rinkes Nucleation and growth of ice crystals inside cultured hepatocytes during freezing in the presence of dimethyl sulfoxide Biophys. J. 65 1993 2524 2536
73. B.J. Luyet, and P.M. Gehenio The mechanism of injury and death by low temperature Biodynamica 3 1940 33 99
74. P.L. Steponkus, J. Wolfe, and M.F. Dowgert Stresses induced by contraction and expansion during a freeze-thaw cycle: A membrane perspective G.J. Morris A. Clarke Effects of low temperatures on biological membranes 1981 Academic Press Toronto 307 322
75. K. Muldrew, and L.E. McGann The osmotic rupture hypothesis of intracellular freezing injury Biophys. J. 66 1994 532 541
76. J. Levitt A sulfhydryl-disulfide hypothesis of frost injury and resistance in plants J. Theor. Biol. 3 1962 355 391
77. A.M. Karow, and W.R. Webb Tissue freezing: A theory for injury and survival Cryobiology 2 1965 99 108
78. J. Farrant, and G.J. Morris Thermal shock and dilution shock as the causes of freezing injury Cryobiology 10 1973 134 140
79. J.E. Lovelock Haemolysis by thermal shock Br. J. Haematol. 1 1955 117 129
80. M. Forsyth, and D.R. MacFarlane Recrystallization revisited Cryo Letters 7 1986 367 378
81. J.O.M. Karlsson A theoretical model of intracellular devitrification Cryobiology 42 2001 154 169
82. H.T. Meryman Cryoprotective agents Cryobiology 8 1971 173 183
83. L.E. McGann Differing actions of penetrating and nonpenetrating cryoprotective agents Cryobiology 15 1978 382 390
84. J.H. Crowe, L.M. Crowe, and J.F. Carpenter Interactions of sugars with membranes Biochim. Biophys. Acta 947 1988 367 384
85. T.J. Anchordoguy, A.S. Rudolph, and J.F. Carpenter Modes of interaction of cryoprotectants with membrane phospholipids during freezing Cryobiology 24 1987 324 331
86. J.E. Lovelock The mechanism of the protective action of glycerol against haemolysis by freezing and thawing Biochim. Biophys. Acta 11 1953 28 36
87. J.E. Lovelock The protective action of neutral solutes against haemolysis by freezing and thawing Biochem. J. 56 1954 265 270
88. P. Mazur Cryobiology: The freezing of biological systems Science 168 1970 939 949
89. C. Polge, A.U. Smith, and A.S. Parkes Revival of spermatozoa after vitrification and dehydration at low temperatures Nature 164 1949 666
90. A.U. Smith Prevention of hemolysis during freezing and thawing of red blood cells Lancet 2 1950 910
91. P.L. Mollison, and H.A. Sloviter Successful transfusion of previously frozen human red cells Lancet 10 1951 862 864
92. C.E. Huggins Reversible agglomeration: A practical method for removal of glycerol from frozen blood W. Spielmann S. Seidl Modern problems in blood preservation 1970 Fischer Verlag Stuggart 138 155
93. C.R. Valeri, A.H. Runck, and C.E. Brodine Recent advances in freeze-preservation of red blood cells JAMA 208 1969 489 492
94. L.L. Haynes, J.L. Tulis, and H.M. Pyle Clinical use of deglycerolized frozen blood JAMA 173 1960 1657
95. H.T. Meryman, and M. Hornblower A method for freezing and washing red blood cells using a high glycerol concentration Transfusion 12 1972 145 156
96. A.W. Rowe, E. Eyster, and A. Kellner Liquid nitrogen preservation of red blood cells for transfusion: A low glycerol-rapid freeze procedure Cryobiology 5 1968 119 128
97. H.W. Krijnen, J.J. De Wit, and C.J. Kuivenhoven Glycerol treated human red cells frozen with liquid nitrogen Vox Sang. 9 1964 559 572
98. J.H. Pert, R. Moore, and P.K. Schork Low-temperature preservation of human erythrocytes: Biochemical and clinical aspects Bibl. Haematol. 19 1965 47 53
99. J.L. Tullis, M.M. Kethel, and H.M. Pyle Studies on the in vivo survival of glycerolized and frozen human red blood cells JAMA 168 1958 399 404
100. H.T. Meryman Frozen red cells Transfus. Med. Rev. 3 1989 121 127
101. J.R. Hess Red cell freezing and its impact on the supply chain Transfus. Med. 14 2004 1 8
102. J.R. Hess, and M.J.G. Thomas Blood use in war and disaster: Lessons from the past century Transfusion 43 2003 1622 1633
103. C.C. Lelkens, F. Noorman, and J.G. Koning Stability after thawing of RBCs frozen with high- and low-glycerol method Transfusion 43 2003 157 164
104. C.R. Valeri, G. Ragno, and L.E. Pivacek In vivo survival of apheresis RBCs, frozen in 40-percent (wt/vol) glycerol and stored after deglycerolization for 15 days at 4°C in AS-3 for up to 21 days Transfusion 41 2001 933 939
105. C.R. Valeri, G. Ragno, and L.E. Pivacek A multicenter study of in vitro and in vivo values in human RBCs frozen with 40-percent (wt/vol) glycerol and stored after deglycerolization for 15 days at 4 degrees C in AS-3: Assessment of RBC processing in the ACP 215 Transfusion 41 2001 933 939
106. C.R. Valeri, C.G. Zaroulis, and J.J. Vecchione Therapeutic effectiveness and safety of outdated human red blood cells rejuvenated to restore oxygen transport function to normal, frozen for 3 to 4 years at -80 C, washed, and stored at 4 C for 24 hours prior to rapid infusion Transfusion 20 1980 159 170
107. G.M. Fahy, D.R. MacFarlane, and C.A. Angell Vitrification as an approach to cryopreservation Cryobiology 21 1984 407 426
108. D.R. MacFarlane Devitrification in glass-forming aqueous solutions Cryobiology 23 1986 230 244
109. G.M. Fahy, D.I. Levy, and S.E. Ali Some emerging principles underlying the physical properties, biological actions and utility of vitrification solutions Cryobiology 24 1987 196 213
110. D.E. Pegg Ice crystals in tissues and organs D.E. Pegg A.M. Karow The biophysics of organ cryopreservation vol. 147 1997 117 140
111. M.M. Strumia, L.S. Colwell, and P.V. Strumia The preservation of blood for transfusion. V. Post-transfusion survival of red cells modified with sugars, frozen, and stored in the frozen state J. Clin. Med. 56 1963 587 593
112. M.L. Bloom, E. Witebski, and A.P. Rinfret Rapidly, hard-frozen blood: Evaluation of progress and clinical survival Bibl. Haematol. 23 1965 642 645
113. C.T. Knorpp, W.R. Merchant, and P.W. Gikas Hydroxyethyl starch: Extracellular cryophylactic agent for erythrocytes Science 157 1967 1312 1313
114. R.J. Williams The surface activity of PVP and other polymers and their antihemolytic capacity Cryobiology 20 1983 521 526
115. P. Boutron, and J. Peyridieu Reduction in toxicity for red blood cells in buffered solutions containing high concentrations of 2,3-butanediol by trehalose, sucrose, sorbitol or mannitol Cryobiology 31 1994 367 373
116. C. Pellerin-Mendes, L. Million, and M. Marchand-Arvier In vitro study of the protective effect of trehalose and dextran during freezing of human red blood cells in liquid nitrogen Cryobiology 35 1997 173 186
117. M.M. Strumia, and P.V. Strumia Recovery and survival of human red cells frozen with albumin, dextran and lactose-albumin Bibl Haematol 19 1964 61 68
118. H.T. Meryman Freezing and vitrification of red cells, recollections and predictions: Quo vadis? S. Sibinga J.D. Cash Transfusion medicine 2001 Kluwer Academic Boston 69 85
119. E.-P. Horn, A. Sputtek, and T. Standl Transfusion of autologous, hydroxyethyl starch-cryopreserved red blood cells Anesth. Analg. 85 1997 739 745
120. A. Sputtek, G. Singbartl, and R. Langer Cryopreservation of red blood cells with the non-penetrating cryoprotectant hydroxyethyl starch Cryo Letters 16 1995 283 288
121. J.H. Crowe, J.F. Carpenter, and L.M. Crowe The role of vitrification in anhydrobiosis Annu. Rev. Physiol. 60 1998 73 103
122. A. Eroglu, M.J. Russo, and R. Bieganski Intracellular trehalose improves the survival of cryopreserved mammalian cells Nat. Biotechnol. 18 2000 163 167
123. J.H. Crowe, L.M. Crowe, and J.F. Carpenter Preserving dry biomaterials: The water replacement hypothesis. Part 1 Biopharm 4 1993 28 33
124. T. Chen, J.P. Acker, and A. Eroglu Beneficial effect of intracellular trehalose on the membrane integrity of dried mammalian cells Cryobiology 43 2001 168 181
125. J.P. Acker, A. Fowler, and B. Lauman Survival of desiccated mammalian cells: Beneficial effects of isotonic media Cell Preserv. Technol. 1 2002 129 140
126. A. Eroglu, M. Toner, and T.L. Toth Beneficial effect of microinjected trehalose on the cryosurvival of human oocytes Fertil. Steril. 77 2002 152 158
127. W.F. Wolkers, N.J. Walker, and F. Tablin Human platelets loaded with trehalose survive freeze-drying Cryobiology 42 2001 79 87
128. S.S. Buchanan, S.A. Gross, and J.P. Acker Cryopreservation of stem cells using trehalose: Evaluation of the method using a human hematopoietic cell line Stem Cells Dev. 13 2004 295 305
129. G. Brumfiel Just add water Nature 428 2004 14 15
130. A.P. MacKenzie The physico-chemical basis for the freeze-drying process Dev. Biol. Stand. 36 1977 51 67
131. H.T. Meryman Freeze-drying H.T. Meryman Cryobiology 1966 Academic Press New York 609 663
132. R.P. Goodrich, S.O. Sowemimo-Coker, and C.R. Zerez Preservation of metabolic activity in lyophilized human erythrocytes Proc. Natl. Acad. Sci. U. S. A. 89 1992 967 971
133. S.O. Sowemimo-Coker, R.P. Goodrich, and C.R. Zerez Refrigerated storage of lyophilized and rehydrated, lyophilized human red cells Transfusion 33 1993 322 329
134. H.T. Meryman Drying of living mammalian cells Ann. N. Y. Acad. Sci. 85 1960 729 739
135. A.P. MacKenzie, and G.L. Rapatz Freeze-drying preservation of human erythrocytes Cryobiology 8 1971 384
136. R.P. Goodrich, and S.O. Sowemimo-Coker Freeze-drying of red blood cells P.L. Steponkus Advances in Low Temperature Biology vol. 2 1993 JAI Press Ltd London 53 99
137. G. Spieles, I. Heschel, and G. Rau An attempt to recover viable human red blood cells after freeze-drying Cryo Letters 17 1996 43 52
138. J.H. Crowe, F.A. Hoekstra, and L.M. Crowe Anhydrobiosis Annu. Rev. Physiol. 54 1992 579 599
139. A.C. Leopold Membranes, metabolism and dry organisms 1986 Cornell University Press Ithaca 374
140. I. Ingram, and D. Bartels The molecular basis of dehydration tolerance in plants Annu. Rev. Plant Physiol. Plant Mol. Biol. 47 1996 377 403
141. A.E. Oliver, O. Leprince, and W.F. Wolkers Non-disaccharide-based mechanisms of protection during drying Cryobiology 43 2001 151 167
142. S.C. Hand, and J.E. Podrabsky Bioenergetics of diapause and quiescence in aquatic animals Thermochim. Acta 349 2000 31 42
143. S.C. Hand, and I. Hardewig Down-regulation of cellular metabolism during environmental stress: Mechanisms and implications Annu. Rev. Physiol. 58 1996 539 563
144. C.A. Rice-Evans, N.J. Miller, and G. Paganga Antioxidant properties of phenolic compounds Trends Plant Sci. 2 1997 152 159
145. S.A. Blackman, R.L. Obendorf, and A.C. Leopold Desiccation tolerance in developing soybean seeds: The role of stress proteins Physiol. Plant. 93 1995 630 638
146. L.M. Crowe Lessons from nature: The role of sugars in anhydrobiosis Comp. Biochem. Physiol., A 131 2002 505 513
147. K.B. Storey, and B.T. Storey Physiology, biochemistry and molecular biology of vertebrate freeze tolerance: The wood frog B.J. Fuller N. Lane E.E. Benson Life in the frozen state 2004 CRC Press New York 243 274
148. J. Wolfe, and G. Bryant Freezing, drying, and/or vitrification of membrane-solute-water systems Cryobiology 39 1999 103 129
149. B.P. Gaber, I. Chandrasekhar, and N. Pattabiraman The interaction of trehalose with the phospholipid bilayer: A molecular modeling study A.C. Leopold Membranes, metabolism and dry organisms 1986 Cornell University Press Ithaca, NY 231 241
150. J.H. Crowe, L.M. Crowe, and J.F. Carpenter Preserving dry biomaterials: The water replacement hypothesis. Part 2 Biopharm 5 1993 40 43
151. F. Franks Thermomechanical properties of amorphous saccharides: Their role in enhancing pharmaceutical product stability Biotechnol. Genet. Eng. Rev. 16 1999 281 292
152. L. Kreilgaard, S. Frokjaer, and J.M. Flink Effects of additives on the stability of recombinant human factor XIII during freeze-drying and storage in the dried solid Arch. Biochem. Biophys. 360 1998 121 134
153. D. Billi, D.H. Wright, and R.F. Helm Engineering desiccation tolerance in Escherichia coli Appl. Environ. Microbiol. 66 2000 1680 1684
154. E. Israeli, B.T. Shaffer, and B. Lighthart Protection of freeze-dried Escherichia coli by trehalose upon exposure to environment conditions Cryobiology 30 1993 519 523
155. S.B. Leslie, E. Israeli, and B. Lighthart Trehalose and sucrose protect both membranes and proteins in intact bacteria during drying Appl. Environ. Microbiol. 61 1995 3592 3597
156. M. Potts Desiccation tolerance of prokaryotes Microbiol. Rev. 58 1994 755 805
157. S.B. Leslie, S.A. Teter, and L.M. Crowe Trehalose lowers membrane phase transitions in dry yeast cells Biochim. Biophys. Acta 1192 1994 7 13
158. P. Cerrutti, M. Segovia de Huergo, and M. Galvagno Commercial baker's yeast stability as affected by intracellular content of trehalose, dehydration procedure and the physical properties of external matrices Appl. Microbiol. Biotechnol. 54 2000 575 580
159. J.C. Slaughter, and T. Nomura Intracellular glycogen and trehalose contents as predictors of yeast viability Enzyme Microb. Technol. 14 1992 64 67
160. R.M. Bieganski, A. Fowler, and J.R. Morgan Stabilization of active recombinant retroviruses in an amorphous dry state with trehalose Biotechnol. Prog. 14 1998 615 620
161. L.M. Crowe, J.H. Crowe, and A.S. Rudolph Preservation of freeze-dried liposomes by trehalose Arch. Biochem. Biophys. 242 1985 240 247
162. A. Garcia de Castro, J. Lapinski, and A. Tunnacliffe Anhydrobiotic engineering Nat. Biotechnol. 18 2000 473
163. A. Garcia de Castro, and A. Tunnacliffe Intracellular trehalose improves osmotolerance but not desiccation tolerance in mammalian cells FEBS Lett. 487 2000 199 202
164. K. Kinosita, and T.Y. Tsong Formation and resealing of pores of controlled sizes in human erythrocyte membrane Nature 268 1977 438 441
165. K. Kinosita, and T.Y. Tsong Survival of sucrose-loaded erythrocytes in the circulation Nature 272 1978 258 260
166. R.S. Franco, R. Barker, and S. Novick Effect of inositol hexaphosphate on the transient behavior of red cells following a DMSO-induced osmotic pulse J. Cell. Physiol. 129 1986 221 229
167. M. Harrison, C. Isaacson, and P. Rathinavelu Resealing of protein tyrosine kinase substrates into human erythrocytes by rapid freezing and thawing in liquid nitrogen M. Magnani J.R. DeLoach The use of resealed erythrocytes as carriers and bioreactors vol. 326 1992 Plenum Press New York 111 118
168. H. Levine Amorphous food and pharmaceutical systems 2002 Royal Society of Chemistry Cambridge 1 351
169. S. Rahman, and M.S. Rahman Handbook of food preservation 1999 Marcel Dekker New York 1 809