Design, synthesis and cytotoxic effect of hydroxy- and 3-alkylaminopropoxy- 9,10-anthraquinone derivatives

Bioorganic and Medicinal Chemistry

Volumn 13, Issue 10, 2005, Pages 3439-3445

  Teng, Chi Huang ^a   Won, Shen Jeu ^b   Lin, Chun Nan ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Anthraquinone derivatives; Cytotoxic; Synthesis

Indexed keywords

1 HYDROXY 3 [3 (ISOPROPYLAMINO)PROPOXYL] 9,10 ANTHRAQUINONE; 1,3 DIHYDROXY 4 PRENYL 9,10 ANTHRAQUINONE; 3 [3 (4 METHYLPIPERAZINOPROPOXY)] 9,10 ANTHRAQUINONE; 3 [3 (BUTYLAMINO)PROPOXY] 1 HYDROXY 9,10 ANTHRAQUINONE; 3 [3 (BUTYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (DIETHYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (ISOBUTYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (ISOPROPYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (PROPYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (TERT BUTYLAMINO)PROPOXY] 1 HYDROXY 9,10 ANTHRAQUINONE; 3 [3 (TERT BUTYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; 3 [3 (TERT CYCLOHEXYLAMINO)PROPOXY] 9,10 ANTHRAQUINONE; ANTHRAQUINONE DERIVATIVE; DNA FRAGMENT; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL DEATH; CELL STRAIN; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG INHIBITION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INCUBATION TIME; STRUCTURE ACTIVITY RELATION;

MINK CELL FOCUS-FORMING VIRUS;

EID: 17444387763     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.03.001     Document Type: Article

References (12)

1. F.R. Kerr J. Pathol. 105 1971 13
2. F.E. Sarrol, and I.D. Bowen Cell Tissue Res. 21 1988 45
3. D.A. Carson, and J.M. Ribeiro Lancet 341 1993 1251
4. B.-L. Wei, S.-H. Wu, M.-I. Chung, S.-J. Won, and C.-N. Lin Eur. J. Med. Chem. 35 2000 1089
5. F. Ojeda, M.I. Guarda, C. Maldonado, and H. Folch Cell Immunol. 125 1990 535
6. V.N. Afanasev, B.A. Korol, Y.A. Mantsygin, P.A. Nelipovich, V.-A. Pechtnikov, and S.-R. Umansky FEBS Lett. 194 1986 347
7. Z. Darzynkiewicz, S. Bruno, G. Del Bino, W. Gorezyca, M.A. Hotz, P. Lassota, and F. Traganas Cytometry 13 1992 795
8. A.H. Wyllic, J.F.R. Kerr, and A.R. Currie Int. Rev. Cytol. 68 1980 251
9. M.J. Arends, and A.H. Wyllic Int. Rev. Exp. Pathol. 32 1991 223
10. C.-M. Tsai, A.F. Gazdar, D.J. Venzon, G.M. Steinberg, R.L. Dedeick, J.L. Mulshine, and B.S. Kramer Cancer Res. 49 1989 2390
11. H.-S. Liu, H. Scrable, D.B. Villaret, M.A. Lieberman, and P. Stambrook Cancer Res. 52 1992 983
12. M.-Y. Chang, M.-S. Jan, S.-J. Wan, and H.-S. Liou Biochem. Biophys. Res. Commun. 248 1998 62