Polymorphism of phase II enzymes: Identification of new enzymes and polymorphic variants by database analysis

Toxicology Letters

Volumn 102-103, Issue , 1998, Pages 149-154

  Board, Philip ^a   Blackburn, Anneke ^a   Jermiin, Lars S ^a   Chelvanayagam, Gareth ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Bioinformatics; Genetic polymorphism; Phase II

Indexed keywords

GLUTATHIONE TRANSFERASE;

CONFERENCE PAPER; DATA BASE; ENZYME ACTIVITY; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; MULTIGENE FAMILY; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOBIOTIC METABOLISM;

AMINO ACID SEQUENCE; DATABASES; GLUTATHIONE TRANSFERASE; ISOENZYMES; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC;

EID: 17344393766     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(98)00300-2     Document Type: Conference Paper

References (17)

1. Ali-Osman, F., Akande, O., Antoun, G., Mao, J.X., Buolamwini, J.M., 1997. Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins. J. Biol. Chem. 272, 10004-10012.
2. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., Lipman, D.J., 1990. Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
3. Anders, M.W., Dekaut, W., Vamvakas, D., 1992. Glutathione-dependent toxicity. Xenobiotica 22, 1135-1145.
4. Board, P.G., 1998. Identification of cDNAs encoding two human alpha class glutathione transferases (GSTA3 and GSTA4) and the heterologous expression of GSTA4-4. Biochem. J. 330, 828-831.
5. Board, P.G., Webb, G.C., Coggan, M., 1989. Isolation of a cDNA clone and localization of the human glutathione S-transferase 3 genes to chromosome bands 11q13 and 12q13-14. Ann. Hum. Genet. 53, 205-213.
6. Board, P.G., Baker, R., Chelvanayagam, G., Jermiin, L., 1997. Zeta, a novel class of glutathione transferases in a range of species from plants to humans. Biochem. J. 328, 929-935.
7. Clarke, D.J., Moghrabi, N., Monaghan, G., Cassidy, A., Boxer, M., Hume, R., Burchell, B., 1997. Genetic defects of the UDP-glucuronosyltransferase-1 (UGT1) gene that cause familial non-haemolytic unconjugated hyperbilirubinaemias. Clin. Chim. Acta. 266, 63-74.
8. Fernandez-Canon, J.M., Penalva, M.A., 1998. Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue. J. Biol. Chem. 273, 329-337.
9. Glatt, H., 1997. Sulfation and sulfotransferases 4: bioactivation of mutagens via sulfation. FASEB J. 11, 314-321.
10. Harries, L.W., Stubbins, M.J., Forman, D., Howard, G.C.W., Wolf, C.R., 1997. Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis 18, 641-644.
11. Harris, M.J., Coggan, M., Langton, L., Wilson, S.R., Board, P.G., 1998. Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer. Pharmacogenetics 8, 27-31.
12. Hayes, J.D., Pulford, D.J., 1995. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. CRC Crit. Rev. Biochem. 30, 445-600.
13. Krynetski, E.Y., Tai, H.L., Yates, C.R., Fessing, M.Y., Loennechen, T., Schuetz, J.D., Relling, M.V., Evans, W.E., 1996. Genetic polymorphism of thiopurine S-methyltransferase: clinical importance and molecular mechanisms. Pharmacogenetics 6, 279-290.
14. Meech, R., Mackenzie, P.I., 1997. Structure and function of uridine diphosphate glucuronosyltransferases. Clin. Exp. Pharmacol. Physiol. 24, 907-915.
15. Menegon, A., Board, P.G., Blackburn, A., Mellick, G.D., LeCouteur, D.G., 1998. Parkinson's disease, pesticides and glutathione transferase polymorphisms. Lancet (in press).
16. Meyer, U.A., 1995. In: Pacifici, G.M., Francchia, G.N. (Eds.) Molecular Genetics of the Acetyltransferases Advances in Drug Metabolism in Man. European Commission, Brussels, pp. 588-606.
17. Tong, Z., Board, P.G., Anders, M.W., 1998. Glutathione transferase zeta catalyses the oxygenation of the carcinogen dichloroacetic acid to glyoxylic acid. Biochem. J. 331, 371-373.