CMV-viraemia during allogenic bone marrow transplantation in paediatric patients: Association with survival and graft-versus-host disease

Bone Marrow Transplantation

Volumn 21, Issue SUPPL. 2, 1998, Pages

  Matthes Martin, S ^a   Aberle, S W ^b   Peters, C ^a   Holter, W ^a   Popow Kraupp, Th ^b   Potschger U ^c   Fritsch, G ^c   Ladenstein, R ^a   Rosenmayer, A ^d   Dieckmann, K ^e   Gadner, H ^a  

^a ST ANNA CHILDREN S HOSPITAL   (Austria)

^b UNIVERSITY OF VIENNA   (Austria)

^c CHILDREN'S CANCER RESEARCH INSTITUTE   (Austria)

^d Austrian Bone Marrow Donor Registry   (Austria)

^e UNIVERSITY OF VIENNA   (Austria)

Author keywords

Children; Cytomegalovirus; Graft versus host disease; PCR

Indexed keywords

BUSULFAN; CYCLOPHOSPHAMIDE; ETOPOSIDE; GANCICLOVIR; MELPHALAN;

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ALLOGENIC BONE MARROW TRANSPLANTATION; BETA THALASSEMIA; CHILD; CHRONIC MYELOID LEUKEMIA; CONFERENCE PAPER; CYTOMEGALOVIRUS INFECTION; DISEASE SEVERITY; FANCONI ANEMIA; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; INCIDENCE; INFANT; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECURRENT VIRUS INFECTION; SURVIVAL; WHOLE BODY RADIATION;

ADOLESCENT; BONE MARROW TRANSPLANTATION; CHILD; CHILD, PRESCHOOL; CYTOMEGALOVIRUS INFECTIONS; FEMALE; GRAFT VS HOST DISEASE; HUMANS; INFANT; LEUKEMIA; MALE; PROSPECTIVE STUDIES; TRANSPLANTATION, HOMOLOGOUS; VIREMIA;

EID: 17344383752     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (14)

1. Link H, Battmer K, Stumme C. Cytomegalovirus in leukocytes after bone marrow transplantation demonstrated by m-RNA in situ hybridisation. Br J Haematol 1993; 85: 573-577.
2. Einsele H, Ehninger G, Hebart H et al. Incidence of local CMV infection and acute intestinal GVHD in marrow transplant recipients with severe diarrhoea. Bone Marrow Transplant 1994; 14: 955-963.
3. Bacigalupo A, Tedone E, Isaza A et al. CMV-antigenemia after allogenic bone marrow transplantation: correlation of CMV-antigen positive cell numbers with transplant-related mortality. Bone Marrow Transplant 1995; 16: 155-161.
4. Olive M, Simsek M, Al-Mufti S. Polymerase chain reaction assay for detection of human cytomegalovirus. Journal of Clinical Microbiology 1989; 27: 1238-1242.
5. Boeckh M, Gallez-Hawkins G, Myerson D et al. Plasma polymerase chain reaction for cytomegalovirus DANN after allogenic marrow transplantation: comparison with polymerase chain reaction using peripheral blood leukocytes, pp65 antigenemia, and viral culture. Transplantation 1997; 64(1): 108-130.
6. Zhuravaskaya T, Maciejewski J, Netski D et al. Spread of Human Cytomegalovirus (HCMV) After Infection of Human Hematopoetic Progenitor Cells: Model of HCMV Latency. Blood 1997; 6: 2482-2491.
7. Goodrich J, Boeckh M, Bowden R. Clinical Infectious Diseases 1994; 19: 287-298.
8. Hagglund H, Bostrom L, Remberger M et al. Risk factors for acute graft-versus-host disease in 291 consecutive HLA-identical bone marrow recipients. Bone Marrow Transplant 1995; 16: 747-753.
9. Einsele H, Waller H, Weber P et al. Cytomegalovirus in liver biopsies of marrow transplant recipients: detection methods, clinical, histological and immunohistological features. Med Microbiol Immunol 1994; 183: 205-216.
10. Lloid M, Schubert M, Myerson D et al. Cytomegalovirus infection of the tongue following marrow transplantation. Bone Marrow Transplant 1994; 14: 99-104.
11. Appleton A, Sviland L, Peiris J et al. Role of target organ infection with cytomegalovirus in the pathogenesis of graft-versus-host disease. Bone Marrow Transplant 1995; 15: 557-561.
12. Söderberg C, Larsson S, Rozell B et al. Cytomegalovirus-induced Cd13-specific Autoimmunity - a possible cause of chronic graft versus-host disease. Transplantation 1996; 4: 600-609.
13. Söderberg C, Sumitran-Karuppan S, Ljungman P et al. CD13-Specific autoimmunity in Cytomegalovirus-infected immunocompromised patients. Transplantation 1996; 4: 594-600.
14. Ringden O, Hermans J, Labopin M et al. The highest leukaemia-free survival after allogenic bone marrow transplantation is seen in patients with grade I acute graft-versus-host disease. Leuk Lymphoma 1996; 24: 71-79.