Real-time observation of affinity reactions using grating couplers: Determination of the detection limit and calculation of kinetic rate constants

Analytical Biochemistry

Volumn 248, Issue 2, 1997, Pages 269-276

  Polzius, Rainer ^a,d   Dießel, Edgar ^b   Bier, Frank F ^c   Bilitewski, Ursula ^a  

^a HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^b BAYER AG   (Germany)

^c MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^d Dräger Medical   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; COENZYMES; EQUILIBRIUM CONSTANTS; EVANESCENT FIELDS; GLYCOPROTEINS; KINETICS; LIGANDS; MOLECULAR WEIGHT;

ASSOCIATION RATE CONSTANTS; EVANESCENT FIELD SENSOR; HUMAN IMMUNOGLOBULIN; IMMOBILIZED RECEPTORS; KINETIC RATE CONSTANTS; OPTICAL GRATING COUPLER; REAL TIME OBSERVATION; SPECIFIC INTERACTION;

RATE CONSTANTS;

AVIDIN; BIOTIN; IMMUNOGLOBULIN; PROTEIN G;

ADSORPTION; ARTICLE; COVALENT BOND; DISSOCIATION; EQUILIBRIUM CONSTANT; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN BINDING;

EID: 17344383350     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1006/abio.1997.2105     Document Type: Article

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