Spatial perturbations within an RNA promoter specifically recognized by a viral RNA-dependent RNA polymerase (RdRp) reveal that RdRp can adjust its promoter binding sites

Journal of Virology

Volumn 73, Issue 1, 1999, Pages 198-204

  Stawicki, Scott Stevenson ^a   Cheng Kao, C ^a  

^a INDIANA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA DIRECTED RNA POLYMERASE; VIRUS ENZYME;

ARTICLE; BINDING SITE; GENE DELETION; GENE INSERTION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN RNA BINDING; RNA STRUCTURE;

EID: 17344373821     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.73.1.198-204.1999     Document Type: Article

References (16)

1. Adkins, S., R. W. Siegel, J. H. Sun, and C. C. Kao. 1997. Minimal templates directing accurate initiation of subgenomic RNA synthesis in vitro by the brome mosaic virus RNA-dependent RNA polymerase. RNA 3:634-647.
2. Adkins, S., S. S. Stawicki, G. Faurote, R. Siegel, and C. C. Kao. 1998. Mechanistic analysis of RNA synthesis by RNA-dependent RNA polymerase from two promoters reveals similarities to DNA-dependent RNA polymerases. RNA 4:455-470.
3. Ahlquist, P. 1992. Bromovirus RNA replication and transcription. Curr. Opin. Genet. Dev. 2:271-276.
4. Bausch, J., F. Kramer, E. Miale, C. Dobkin, and D. Mills. 1983. Terminal adenylation in the synthesis of RNA by Qβ replicase. J. Biol. Chem. 258:1978-1984.
5. Dreher, T. W., and T. C. Hall. 1988. Mutational analysis of the sequence and structural requirements in brome mosaic virus RNA for minus strand promoter activity. J. Mol. Biol. 201:31-40.
6. Fodor, E., B. L. Seong, and G. G. Brownlee. 1993. Photochemical crosslinking of influenza A polymerase to its virion RNA promoter defines a polymerase binding site at residues 9 to 12 of the promoter. J. Gen. Virol. 74:1327-1333.
7. Fodor, E., D. C. Pritlove, and G. G. Brownlee. 1995. Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus. J. Virol. 69:4012-4019.
8. Frankel, A., and A. Smith. 1998. Induced folding in RNA-protein recognition: more than a simple molecular handshake. Cell 92:149-151.
9. Gelles, J., and R. Landick. 1998. RNA polymerase as a molecular motor. Cell 93:13-16.
10. Goldbach, R., O. LeGall, and J. Wellink. 1991. Alpha-like viruses in plants. Semin. Virol. 2:19-25.
11. Ikeda, R., L. L. Chang, and G. S. Warshamana. 1993. Selection and characterization of a mutant T7 RNA polymerase that recognizes an expanded range of T7 promoter-like sequences. Biochemistry 32:9115-9124.
12. Joyce, C. M. 1997. Choosing the right sugar: how polymerases select a nucleotide substrate. Proc. Natl. Acad. Sci. USA 94:1619-1622.
13. 12a.Kao, C. C. Unpublished data.
14. Kao, C. C., and J. H. Sun. 1996. Initiation of minus-strand RNA synthesis by the brome mosaic virus RNA-dependent RNA polymerase: use of oligoribonucleotide primers. J. Virol. 70:6826-6830.
15. Klement, J. F., M. B. Moorefield, E. Jorgensen, J. E. Brown, S. Risman, and W. T. McAllister. 1990. Discrimination between bacteriophage T3 and T7 promoters by the T3 and T7 RNA polymerases depend primarily upon a three base-pair region located 10-12 base-pairs upstream from the start site. J. Mol. Biol. 215:21-29.
16. Lai, M. M. 1998. Cellular factors in the transcription and replication of viral RNA genomes. A parallel to DNA-dependent RNA transcription. Virology 244:1-12.