Effects of genotype and diet on cholesterol efflux into plasma and lipoproteins of normal, apolipoprotein A-I-, and apolipoprotein E-deficient mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 10, 1997, Pages 2010-2019

  Huang, Yadong ^a   Zhu, Yanhong ^a   Langer, Claus ^a   Raabe, Martin ^a   Wu, Shili ^a   Wiesenhütter, Bernd ^a   Seedorf, Udo ^a   Maeda, Nobuyo ^b   Assmann, Gerd ^a   Von Eckardstein, Arnold ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Animal models; Atherosclerosis; HDL subclasses; Reverse cholesterol transport

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN E;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DIETARY INTAKE; ELECTROPHORETIC MOBILITY; ESTERIFICATION; FAT INTAKE; FIBROBLAST; GENOTYPE; LIPID TRANSPORT; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN DEFICIENCY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 17344368989     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.10.2010     Document Type: Article

References (18)

1. Fielding CJ, Fielding PE. Molecular physiology of reverse cholesterol transport. J Lipid Res. 1995;36:211-228.
2. von Eckardstein A, Huang Y, Assmann G. Physiological role and clinical relevance of high-density lipoprotein subclasses. Curr Opin Lipidol. 1994;5:404-416.
3. Barrans A, Jaspard B, Barbaras R, Chap H, Perret B, Collet X. Pre-β-HDL: structure and metabolism. Biochim Biophys Acta. 1996;1300:73-85.
4. Castro GR, Fielding CJ. Early incorporation of cell-derived cholesterol into pre-β-migrating high density lipoprotein. Biochemistry 1988;27:25-29.
5. Czarnecka H, Yokoyama S. Regulation of cellular cholesterol efflux by lecithin: cholesterol acyltransferase reaction through nonspecific lipid exchange. J Biol Chem. 1996;266:2023-2028.
6. Czarnecka H, Yokoyama S. Lecithin: cholesterol acyltransferase reaction on cellular lipid released by free apolipoprotein-mediated efflux. Biochemistry 1995;34:4385-4392.
7. von Eckardstein A. Cholesterol efflux from macrophages and other cells. Curr Opin Lipidol. 1996;7:311-320.
8. Kawano M, Miida T, Fielding CJ, Fielding PE. Quantitation of preβ-HDL-dependent and nonspecific components of the total efflux of cellular cholesterol and phospholipid. Biochemistry 1993;32:5025-5028.
9. Fielding PE, Kawano M, Catapano A, Zoppo A, Marcovina S, Fielding CJ. Unique epitope of apolipoprotein A-I in pre-β-1 high density lipoprotein and its role in the catalyzed efflux of cellular cholesterol. Biochemistry 1994;33:6981-6985.
10. Fielding CJ, Moser A. Evidence for the separation of albumin- and apo A-I-dependent mechanisms of cholesterol efflux from cultured fibroblasts into human plasma. J Biol Chem. 1982;257:10955-10960.
11. Römling R, von Eckardstein A, Funke H, Motti C, Fragiacomo G, Noseda G, Assmann G. A nonsense mutation in the apolipoprotein A-I gene is associated with high density lipoprotein deficiency but not with coronary heart disease. Arterioscler Thromb. 1994;14:1915-1923.
12. Assmann G, von Eckardstein A, Funke H. High density lipoproteins, reverse transport of cholesterol, and coronary heart disease: insights from mutants. Circulation 1993;87(suppl. III):28-34.
13. Huang Y, von Eckardstein A, Wu S, Maeda N, Assmann G. A plasma lipoprotein containing only apolipoprotein E and with γ mobility on electrophoresis releases cholesterol from cells. Proc Natl Acad Sci USA. 1994;91:1834-1838.
14. von Eckardstein A, Huang Y, Wu S, SaadatSarmadi S, Schwarz S, Steinmetz A, Assmann G. High density lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma. Arterioscler Thromb Vasc Biol. 1995;15:1755-1763.
15. Fazio S, Yao Z. The enhanced association of apolipoprotein E with apolipoprotein B-containing lipoproteins in serum-stimulated hepatocytes occurs intracellularly. Arterioscler Thromb Vasc Biol. 1995;15:593-600.
16. von Eckardstein A, Huang Y, Wu S, Funke H, Noseda G, Assmann G. Reverse cholesterol transport in plasmas of patients with different forms of familial high density lipoprotein deficiency. Arterioscler Thromb Vasc Biol. 1995;15:691-703.
17. Piedrahita, Zhang SH, Hagamann J, Oliver PM, Maeda N. Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci USA. 1992;89:4471-4475.
18. Williamson R, Lee D, Hagamann J, Maeda N. Marked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-I. Proc Natl Acad Sci USA. 1992;89:7134-7138.