Effect of treadmill exercise on bone mass in female rats

Experimental Animals

Volumn 54, Issue 1, 2005, Pages 1-6

  Iwamoto, Jun ^a   Takeda, Tsuyoshi ^a   Sato, Yoshihiro ^b  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Mitate Hospital   (Japan)

Author keywords

Female rat; Mechanical loading; Treadmill running exercise

Indexed keywords

CALCITRIOL; CALCIUM; PARATHYROID HORMONE;

BIOMECHANICS; BONE GROWTH; BONE MASS; BONE MATURATION; BONE MINERAL; BONE STRENGTH; CALCIUM BLOOD LEVEL; CANCELLOUS BONE; CORTICAL BONE; DUAL ENERGY X RAY ABSORPTIOMETRY; FALLING; FEMALE; FEMUR; FRAGILITY FRACTURE; LUMBAR VERTEBRA; MENOPAUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOPENIA; OVARIECTOMY; PARATHYROID HORMONE BLOOD LEVEL; REVIEW; TIBIA; TREADMILL EXERCISE; VITAMIN BLOOD LEVEL; WEIGHT BEARING; ANIMAL; ANIMAL EXPERIMENT; BONE DENSITY; BONE DEVELOPMENT; EXERCISE; EXERCISE TEST; HUMAN; METABOLIC BONE DISEASE; METABOLISM; PHYSIOLOGY; POSTMENOPAUSE OSTEOPOROSIS; RAT; TIME;

ANIMALS; BONE DENSITY; BONE DISEASES, METABOLIC; BONE RESORPTION; CALCITRIOL; CALCIUM; EXERCISE; EXERCISE TEST; FEMALE; HUMANS; OSTEOGENESIS; OSTEOPOROSIS, POSTMENOPAUSAL; OVARIECTOMY; PARATHYROID HORMONE; PHYSICAL CONDITIONING, ANIMAL; RATS; TIME FACTORS; WEIGHT-BEARING;

EID: 17244375184     PISSN: 13411357     EISSN: None     Source Type: Journal    
DOI: 10.1538/expanim.54.1     Document Type: Review

References (31)

1. Barengolts, E.I., Curry, D.J., Bapna, M.S., and Kukreja, S.C. 1993. Effects of two non-endurance exercise protocols on established bone loss in ovariectomized adult rats. Calcif. Tissue Int. 52:239-243.
2. Barengolts, E.I., Curry, D.J., Bapna, M.S., and Kukreja, S.C. 1993. Effects of endurance exercise on bone mass and mechanical properties in intact and ovariectomized rats. J. Bone Miner. Res. 8:937-942.
3. Barengolts, E.I., Lathon, P.V., Curry, D.J., and Kukreja, S.C. 1994. Effects of endurance exercise on bone histomorphometric parameters in intact and ovariectomized rats. Bone Miner. 6:133-140.
4. Bourrin, S., Palle, S., Pupier, R., Vico, L., and Alexandre, C. 1995. Effect of physical training on bone adaptation in three zones of the rat tibia. J. Bone Miner. Res. 10:1745-1752.
5. Chen, M.M., Yeh, J.K., Aloia, J.F., Tierney, J.M., and Sprintz, S. 1994. Effect of treadmill execise on tibial cortical bone in aged female rats: A histomorphometry and dual energy x-ray absorptiometry study. Bone 15:313-319.
6. Darnley, M.J., DiMarco, N.M., and Aukema, H.M. 2000. Safety of chronic exercise in a rat model of kidney disease. Med. Sci. Sports Exerc. 32:576-580.
7. Frost, H.M. and Jee, W.S.S. 1992. On the rat model of human osteopenias and osteoporoses. Bone Miner. 18:227-236.
8. Fukuda, S., Iida, H., and Yan, X. 2002. Preventive effects of running exercise on bones in heavy ion particle irradiated rats. J. Radiat. Res. 43 (Suppl): S233-S238.
9. Huang, T.H., Yang, R.S., Hsieh, S.S., and Liu, S.H. 2002. Effects of caffeine and exercise on the development of bone: a densitometric and histomorphometric study in young Wistar rats. Bone 30:293-299.
10. Iwamoto, J., Takeda, T., and Ichimura, S. 1998. Effects of exercise on bone mineral density in mature osteopenic rats. J. Bone Miner. Res. 13:1308-1317.
11. Iwamoto, J., Takeda, T., Ichimura, S., and Ushiku, N. 1998. Effects of moderate running exercise on bone mass and bone metabolism in mature osteopenic rats. J. Jpn. Soc. Bone Morphom. 8:107-117.
12. Iwamoto, J., Yeh, J.K., and Aloia, J.F. 1999. Differential effect of treadmill exercise on three cancellous bone sites in the young growing rat. Bone 24:163-169.
13. Iwamoto, J., Yeh, J.K., and Aloia, J.F. 2000. Effect of deconditioning on cortial and cancellous bone growth in the exercise trained young rats. J. Bone Miner. Res. 15:1842-1849.
14. Iwamoto, J., Shimamura, C., Takeda, T., Abe, H., Ichimura, S., Sato, Y., and Toyama, Y. 2004. Effects of treadmill exercise on bone mass, bone metabolism, and calciotropic hormones in young growing rats. J. Bone Miner. Metab. 22:26-31.
15. Kannus, P., Sievanen, H., Jarvinen, T.L., Jarvinen, M., Kvist, M., Oja, P., Vouri, I., and Jozsa, L. 1994. Effects of free mobilization and low- to high-intensity treadmill running on the immobilization-induced bone loss in rats. J. Bone Miner. Res. 9:1613-1619.
16. Mosekilde, L., Danielsen, C.C., Sogaard, C.H., and Thorling, E. 1994. The effect of long-term exercise on vertebral and femoral bone mass, dimensions, and strength - assessed in a rat model. Bone 15:293-301.
17. Oxlund, H., Anderson, N.B., Ortoft, G., Orskov, H., and Andreassen, T.T. 1998. Growth hormone and mild exercise in combination markedly enhance cortical bone formation and strength in old rats. Endocrinology 139: 1899-1904.
18. Reed, A.H., McCarty, H.L., Evans, G.L., Turner, R.T., and Westerlind, K.C. 2002. The effects of chronic alcohol consumption and excercise on the skeleton of adult male rats. Alcohol Clin, Exp. Res. 26:1269-1274.
19. Tuukkanen, J., Peng, Z., and Vaananen, H.K. 1994. Effect of running exercise on the bone loss induced by orchidectomy in the rat. Calcif. Tissue. Int. 55:33-37.
20. Yamamoto, N., Takahashi, H.E., Tanizawa, T., Fujimoto, R., Hara, T., and Tanaka, S.,1993. Maintenance of bone mass by physical exercise after discontinuation of intermittent hPTH (1-34) administration. Bone Miner. 23:333-342.
21. Yamazaki, I. and Yamaguchi, H. 1989. Characteristics of an ovariectomized osteopenic rat model. J. Bone Miner. Res. 4: 13-22.
22. Yeh, J.K., Aloia, J.F., and Yasumura, S. 1989. Effect of physical activity on calcium and phosphorus metabolism in the rat. Am. J. Physiol. 256:E1-E6.
23. Yeh, J.K., and Aloia, J.F. 1990. Effect of physical activity on calciotropic hormones and calcium balance in rats. Am. J. Physiol. 258: E263-E268.
24. Yeh, J.K. and Aloia, J.F. 1990. Deconditioning increases bone resorption and decreases bone formation in the rat. Metabolism 39:659-663.
25. Yeh, J.K., Liu, C.C., and Aloia, J.F. 1993. Effects of exercise and immobilization on bone formation and resorption in young rats. Am. J. Physiol. 264: E182-E189.
26. Yeh, J.K., Aloia, J.F., Chen, M.M., Tierney, J.M., and Sprintz, S. 1993. Influence of exercise on cancellous bone of the aged female rat. J. Bone Miner. Res. 8: 1117-1125.
27. Yeh, J.K., Aloia, J.F., Tierney, J.M., and Sprintz, S. 1993. Effect of treadmill exercise on vertebral and tibial bone mineral content and bone mineral density in the aged adult rat: Determined by dual energy X-ray absorptiometry. Calcif. Tissue Int. 52: 234-238.
28. Yeh, J.K., Liu, C.C., and Aloia, J.F. 1993. Additive effect of treadmill exercise and 17β-estradoil replacement on prevention of tibial bone loss in adult ovariectomized rat. J. Bone Miner. Res. 8: 677-683.
29. Yeh, J.K., Aloia, J.F., and Barilla, M.L. 1994. Effects of 17β-estradiol replacement and treadmill exercise on vertebral and femoral bones of the ovariectomized rat. Bone Miner. 24: 223-234.
30. Yeh. J.K., Aloia, J.F., and Chen, M. 1994. Growth hormone administration potentiates the effect of treadmill exercise on long bone formation but not on the vertebrae in middle-aged rats. Calcif. Tissue Int. 54:38-43.
31. Yeh, J.K., Aloia, J.F., Chen, M., Ling, N., Koo, H.C., and Millard, W.J. 1994. Effect of growth hormone administration and treadmill exercise on serum and skeletal IGF-I in rats. Am. J. Physiol. 266: E129-E135.