Molecular recognition of an ADP-ribosylating Clostridium botulinum C3 exoenzyme by RalA GTPase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 15, 2005, Pages 5357-5362

  Holbourn, Kenneth P ^a   Sutton, J Mark ^b   Evans, Hazel R ^a   Shone, Clifford C ^b   Acharya, K Ravi ^a  

^a University of Bath   (United Kingdom)

^b PUBLIC HEALTH ENGLAND   (United Kingdom)

Author keywords

ADP ribosylation; Protein protein interaction; X ray crystallography

Indexed keywords

BACTERIAL ENZYME; EXOENZYME C3; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; BACILLUS CEREUS; CLOSTRIDIUM; CLOSTRIDIUM BOTULINUM; CLOSTRIDIUM LIMOSUM; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME INHIBITION; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TARGET CELL;

ADP RIBOSE TRANSFERASES; AMINO ACID SEQUENCE; BINDING SITES; BOTULINUM TOXINS; CLOSTRIDIUM BOTULINUM; CRYSTALLOGRAPHY, X-RAY; GUANOSINE DIPHOSPHATE; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; RAL GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

BACILLUS CEREUS; CLOSTRIDIUM BOTULINUM; CLOSTRIDIUM LIMOSUM; STAPHYLOCOCCUS AUREUS;

EID: 17244365578     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0501525102     Document Type: Article

References (43)

1. Passador, L. & Iglewski, W. (1994) Methods Enzymol. 235, 617-631.
2. Kreuger, K. M. & Barbieri, J. T. (1995) Clin. Microbiol. Rev. 8, 34-47.
3. Popoff, M. R., Hauser, D., Boquet, P., Eklund, M. W. & Gill, D. M. (1991) Infect. Immun. 59, 3673-3679.
4. Aktories, K., Rosener, S., Blaschke, U. & Chhatwal, G. S. (1988) Eur. J. Biochem. 172, 445-450.
5. Wilde, C. & Aktories, K. (2001) Toxicon 39, 1647-1660.
6. Aktories, K., Braun, U., Rosener, S., Just, I. & Hall, A. (1989) Biochem. Biophys. Res. Commun. 158, 209-213.
7. Chardin, P., Boquet, P., Madaule, F., Popoff, M. R., Rubin, E. J. & Gill, D. M. (1989) EMBO J. 8, 1087-1092.
8. Williamson, K. C. L., Smith, A., Moss, J. & Vaughan, M. (1990) J. Biol. Chem. 265, 32820-32829.
9. Aktories, K. & Hall, A. (1989) Trends Pharmacol. Sci. 10, 415-418.
10. Wilde, C., Chhatwal, G. S., Schmalzing, G., Aktories, K. & Just, I. (2001) J. Biol. Chem. 276, 9537-9542.
11. Ridley, A. J. (2001) Trends Cell Biol. 11, 471-477.
12. Rubin, E. J., Gill, D. M., Boquet, P. & Popoff, M. R. (1988) Mol. Cell. Biol. 8, 418-426.
13. Lehmann, M., Fournier, A., Selles-Navarro, I., Dergham, P., Sebok, A., Leclerc, N., Tigyi, G. & McKerracher, L. (1999) J. Neurosci. 19, 7537-7547.
14. Watanabe, Y., Morimatsu, M. & Syuto, B. (2000) J. Vet. Med. Sci. 62, 473-478.
15. Wilde, C., Barth, H., Sehr, P., Han, L., Schmidt, M., Just, I. & Aktories, K. (2002) J. Biol. Chem. 277, 14771-14776.
16. Chardin, P. & Tavitian, A. (1986) EMBO J. 5, 2203-2208.
17. Urano, T., Emkey, R. & Feig, L. A. (1996) EMBO J. 15, 810-816.
18. Ohta, Y., Suzuki, N., Nakamura, S., Hartwig, J. H. & Stossel, T. P. (1999) Proc. Natl. Acad. Sci. USA 96, 2122-2128.
19. Nakashima, S., Morinaka, K., Koyama, S., Ikeda, M., Kishida, M., Okawa, K., Iwamatsu, A., Kishida, S. & Kikuchi, A. (1999) EMBO J. 18, 3629-3642.
20. Jullien-Flores, V., Dorseuil, O., Romero, F., Letourneur, F., Saragosti, S., Berger, R., Tavitian, A., Gacon, G. & Camonis, J. H. (1995) J. Biol. Chem. 270, 22473-22477.
21. Moskalenko, S., Henry, D. O., Rosse, C., Mirey, G., Camonis, J. H. & White, M. A. (2002) Nat. Cell Biol. 4, 66-72.
22. Sugihara, K., Asano, S., Tanaka, K., Iwamatsu, A., Okawa, K. & Ohta, Y. (2002) Nat. Cell Biol. 4, 73-78.
23. Chien, Y. & White, M. A. (2003) EMBO Rep. 4, 800-806.
24. Han, S., Arvai, A. S., Clancy, S. B. & Tainer, J. A. (2001) J. Mol. Biol. 305, 95-107.
25. Evans, H. R., Holloway, D. E., Sutton, J. M., Ayriss, J., Shone, C. C. & Acharya, K. R. (2004) Acta Crystallogr. D 60, 1502-1155.
26. Menetrey, J., Flatau, G., Stura, E. A., Charbonnier, J. B., Gas, F., Teulon, J. M., Le Du, M. H., Boquet, P. & Menez, A. (2002) J. Biol. Chem. 277, 30950-30957.
27. Evans, H. R., Sutton, J. M., Holloway, D. E., Ayriss, J., Shone, C. C. & Acharya, K. R. (2003) J. Biol. Chem. 278, 45924-45930.
28. Fukai, S., Matern, H. T., Jagath, J. R., Scheller, R. H. & Brunger, A. T. (2003) EMBO J. 22, 3267-3278.
29. Otwinowski, Z. (1993) DENZO: An Oscillation Data Processing Program for Macromolecular Crystallography (Yale Univ. Press, New Haven, CT).
30. Otwinowski, Z. (1993) SCALEPACK: Software for the Scaling Together of Integrated Intensities Measured on a Number of Separate Diffraction Images (Yale Univ. Press, New Haven, CT).
31. Collaborative Computational Project, No. 4 (1994) Acta Crystallogr. D 50, 760-763.
32. Vagin, A. & Teplyakov, A. (2000) Acta Crystallogr. D 56, 1622-1624.
33. Murshudov, G. N. (1997) Acta Crystallogr. D 53, 240-255.
34. Brünger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., GrosseKunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., et al. (1998) Acta Crystallogr. D 54, 905-921.
35. Jones, T. A., Zou, J. Y., Cowan, S. W. & Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 109-110.
36. Brünger, A. T. (1992) Nature 355, 472-474.
37. Esnouf, R. M. (1997) J. Mol. Graphics 15, 132-134.
38. Laskowski, R. A., MacArthur, M. W., Moss, D. S. & Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291.
39. Takai, Y., Sasaki, T. & Matozaki, T. (2001) Physiol. Rev. 81, 153-208.
40. Sekine, A., Fujiwara, M. & Narumiya, S. (1989) J. Biol. Chem. 264, 8602-8605.
41. Wilde, C., Genth, H., Aktories, K. & Just, I. (2000) J. Biol. Chem. 275, 16478-16483.
42. Rajamani, D., Thiel, S., Vajda, S. & Camacho, C. J. (2004) Proc. Natl. Acad. Sci. USA 101, 11287-11292.
43. Notredame, C., Higgins, D. G. & Heringa, J. (2000) J. Mol. Biol. 302, 205-217.