Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains

Journal of Biological Chemistry

Volumn 278, Issue 20, 2003, Pages 18330-18335

  Müller, Carsten ^a   Richter, Susanne ^b   Rinas, Ursula ^c  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

^b CYTOS BIOTECHNOLOGY AG   (Switzerland)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BLOOD; DIMERS; ENTHALPY; MONOMERS; REDOX REACTIONS;

PLATELETS;

GROWTH KINETICS;

CYSTEINE; DIMER; DISULFIDE; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR AA; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; GUANIDINE; ISOPROTEIN; PLATELET DERIVED GROWTH FACTOR;

ARTICLE; CHEMICAL REACTION KINETICS; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; ENTHALPY; GEL PERMEATION CHROMATOGRAPHY; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN FOLDING; CHEMICAL MODEL; CHEMISTRY; ENZYME ACTIVATION; ESCHERICHIA COLI; HUMAN; KINETICS; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE; THERMODYNAMICS; TIME;

DIMERIZATION; DISULFIDES; ENZYME ACTIVATION; ESCHERICHIA COLI; GUANIDINE; HUMANS; KINETICS; MODELS, CHEMICAL; PLATELET-DERIVED GROWTH FACTOR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; TEMPERATURE; THERMODYNAMICS; TIME FACTORS;

EID: 17144472332     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212317200     Document Type: Article

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