American families with Crohn's disease have strong evidence for linkage to chromosome 16 but not chromosome 12

Gastroenterology

Volumn 115, Issue 5, 1998, Pages 1056-1061

  Brant, S R ^a   Fu, Y ^a   Fields, C T ^a   Baltazar, R ^a   Ravenhill, G ^a   Pickles, M R ^a   Rohal, P M ^a   Mann, J ^a   Kirschner, B S ^a   Jabs, E W ^a   Bayless, T M ^a   Hanauer, S B ^a   Cho, J H ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

ARTICLE; CHROMOSOME 12; CHROMOSOME 16; CHROMOSOME 3P; CHROMOSOME 7Q; CONTROLLED STUDY; CROHN DISEASE; ETHNOLOGY; FAMILIAL DISEASE; GENETIC LINKAGE; GENETIC MARKER; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; JEW; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; UNITED STATES;

EID: 17144472209     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70073-3     Document Type: Article

References (24)

1. EV Loftus Jr MD Silverstein WJ Sandborn WJ Tremaine WS Harmsen AR Zinsmeister Crohn's disease in Olmsted County, Minnesota, 1940-1993: incidence, prevalence and survival Gastroenterology 114 1998 1161 1168
2. RS Sandler Epidemiology SR Targan F Shanahan Inflammatory bowel disease: from bench to bedside 1994 Williams & Wilkins Baltimore, MD 5 30
3. H Yang JI Rotter Genetics of inflammatory bowel disease SR Targan F Shanahan Inflammatory bowel disease: from bench to bedside 1994 Williams & Wilkins Baltimore, MD 32 64
4. C Tysk E Lindberg G Jarnerot B Floderus-Myrhed Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking Gut 29 1988 990 996
5. H Yang C McElree MP Roth F Shanahan SR Targan JI Rotter Familial empiric risks for inflammatory bowel disease: differences between Jews and non-Jews Gut 34 1993 517 524
6. JP Hugot P Laurent-Puig C Gower-Rousseau JM Olson JC Lee L Beaugerie I Naom JL Dupas A VanGossum M Orholm C Bonaiti-Pellie J Weissenbach CG Mathew JE Lennard-Jones A Cortot JF Colombel G Thomas Mapping of a susceptibility locus for Crohn's disease on chromosome 16 Nature 379 1996 821 823
7. J Satsangi M Parkes E Louis M Lathrop J Bell DP Jewell Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12 Nat Genet 14 1996 199 202
8. RH Duerr MM Barmada L Zhang S Davis RA Preston LJ Chensny JL Brown GD Ehrlich DE Weeks CE Aston Linkage and association between inflammatory bowel disease and a locus on chromosome 12 Am J Hum Genet 63 1998 95 100
9. E Lander L Kruglyak Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results Nat Genet 11 1995 241 247
10. DK Podolsky Inflammatory bowel disease N Engl J Med 325 1991 928 937 and 1008-1016
11. C Gower-Rousseau JL Salomez JL Dupas R Marti MC Nuttens A Votte M Lemahieu B Lemaire JF Colombel A Cortot Incidence of inflammatory bowel disease in northern France (1988-1990) Gut 35 1994 1433 1438
12. B Yuan D Vaske JL Weber J Beck VC Sheffield Improved set of short tandem repeat polymorphisms for screening the human genome Am J Hum Genet 60 1997 459 460
13. 1st ed N Dracopoli JL Haines BR Korf DT Moir CC Morton CE Seidman JG Seidman DR Smith Current protocols in human genetics 1994 John Wiley & Sons, New York
14. SC Kogan Boherty J Gitschier An improved method for prenatal diagnosis of genetic diseases by analysis of amplified DNA sequences N Engl J Med 317 1987 985 990
15. M Litt X Hauge V Sharma Shadow bands seen when typing polymorphic dinucleotide repeats: some causes and some cures Biotechniques 15 1993 280 284
16. L Kruglyak MJ Daly MP Reeve-Daly ES Lander Parametric and nonparametric linkage analysis: a unified multipoint approach Am J Hum Genet 58 1996 1347 1363
17. L Kruglyak ES Lander Complete multipoint sib-pair analysis of qualitative and quantitative traits Am J Hum Genet 57 1997 439 454
18. CS Probert V Jayanthi AO Hughes JR Thompson AC Wicks JF Mayberr y Prevalence and family risk of ulcerative colitis and Crohn's disease: an epidemiological study among Europeans and south Asians in Leicestershire Gut 34 1993 1547 1551
19. M Orholm P Munkholm E Langholz OH Nielsen TI Sorensen V Binder Familial ocurrence of inflammatory bowel disease N Engl J Med 324 1991 84 88
20. JH Cho DL Nicolae L Gold C Fields MC LaBuda PM Rohal MR Pickles L Qin Y Fu JS Mann BS Kirschner EW Jabs J Weber SB Hanauer TM Bayless SR Brant Identification of novel susceptibility loci for inflammatory bowel disease on chromo-somes 1p, 3q, 4q: evidence for epistasis between 1p and IBD1 Proc Natl Acad Sci U S A 95 1998 7502 7507
21. JI Bell GM Lathrop Multiple loci for multiple sclerosis Nat Genet 13 1996 377 378
22. ES Lander NJ Schork Genetic dissection of complex traits Science 265 1994 2037 2048
23. JD Ohmen HY Yang KK Yamamoto HY Zhao M Yuanhong LG Bentley Z Haung S Gerwehr S Pressman C McElree S Targan JI Rotter N Fischel-Ghodsian Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis Hum Mol Genet 5 1996 1679 1684
24. M Parkes J Satsangi A Merriman DP Jewell Precision mapping of chromosome 12 linkage in IBD: evidence for a haplotype association (abstr) Gastroenterology 114 1998 A1058 Received March 18, 1998. Accepted June 30, 1998