Protective Immune Responses toTheileria Annulata of Relevance to Vaccine Development

Tropical Animal Health and Production

Volumn 29, Issue , 1997, Pages 136S-138S

  Preston, Patricia M ^a   Visser, Astrid ^a   Abraham, A ^a   Richardson, Wendy ^a   Richardson, Jeanette ^a   Forsyth, Lynn ^a   Bell Sakyi, Lesley ^b   Wilkie, Gwen ^b   Entrican, G ^c   Boid, R ^b   Spooner, R L ^b   Brown, C G D ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c Moredun Animal Health   (United Kingdom)

Author keywords

East Coast Fever; European Union; Innate Immune Mechanism; Natural Killer Cell Activity; Nitric Oxide

Indexed keywords

PARASITE ANTIGEN; PROTOZOAL VACCINE;

ANIMAL; ANIMAL PARASITOSIS; ARTICLE; CATTLE; CATTLE DISEASE; GROWTH, DEVELOPMENT AND AGING; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MACROPHAGE; MACROPHAGE ACTIVATION; NATURAL KILLER CELL; THEILERIA ANNULATA;

ANIMALS; ANTIGENS, PROTOZOAN; CATTLE; CATTLE DISEASES; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; MACROPHAGE ACTIVATION; MACROPHAGES; PROTOZOAN VACCINES; THEILERIA ANNULATA; THEILERIASIS;

EID: 17144461055     PISSN: 00494747     EISSN: 15737438     Source Type: Journal    
DOI: 10.1007/BF02632954     Document Type: Article

References (11)

1. Entrican G., McInnes C. J., Logan M., Preston P. M., Martinod S. &Brown C. G. D. (1991). Production of interferons by bovine and ovine cell lines infected withTheileria annulata orTheileria parva.Parasite Immunology 13, 339–343.
2. Fearon D. T. &Locksley R. M. (1996). The instructive role of innate immunity in the acquired immune response.Science,272, 50–54.
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4. Preston P. M. &Brown C. G. D. (1985). Inhibition of lymphocyte invasion by sporozoites and the transformation of trophozoite-infected lymphocytesin vitro by serum fromTheileria annulata immune cattle.Parasite Immunology 7, 301–314.
5. Preston P. M. &Brown C. G. D. (1988). Macrophage mediated cytostasis and lymphocyte cytotoxixcity in cattle immunised withTheileria annulata sporozoites or macroschizont-infected cell lines.Parasite Immunology 10, 631–647.
6. Preston P. M., Brown C. G. D. &Spooner R. L. (1983). Cell mediated cytotoxicity inTheileria annulata infection with evidence for BoLA restriction.Clinical & Experimental Immunology 53, 88–100.
7. Preston P. M., Brown C. G. D., Bell-Sakyi L. J., Richardson W. &Sanderson A. (1992a). Tropical theileriosis inBos taurus andBos taurus × Bos indicus calves. Response to infection with graded doses of sporozoites.Research in Veterinary Science 53, 230–243.
8. Preston P. M., Brown C. G. D. &Richardson W. (1992b). Cytokines inhibit the development of trophozoite-infected cells ofTheileria annulata andTheileria parva but enhance the proliferation of macroschizont-infected cell lines.Parasite Immunology 14, 125–141.
9. Preston P. M., Brown C. G. D., Entrican G., Richardson W. &Boid R. (1993). Synthesis of tumour necrosis factor alpha and interferons by mononuclear cells fromTheileria annulata infected cettle.Parasite Immunology 15, 525–534.
10. Richardson J. O., Forsyth L. M. G., Brown C. G. D. & Preston P. M. (1997). Nitric oxide causes the macroschizonts ofTheileria annulata to disappear and host cells to become apoptotic.Veterinary Research Communications in press.
11. Visser A., Abraham A., Bell-Sakyi L. J., Brown C. G. D. &Preston P. M. (1995). Nitric oxide inhibits the establishment of macroschizont-infected cell lines and is produced by macrophages of calves undergoing bovine tropical theileriosis and East Coast fever.Parasite Immunology 17, 91–102.