Cytogenetic analysis of 477 psoriatics revealed an increased frequency of aberrations involving chromosome region 11q

European Journal of Human Genetics

Volumn 7, Issue 3, 1999, Pages 339-344

  Enerbäck, Charlotta ^a   Holmqvist, Deborah ^a   Inerot, Annica ^a   Enlund, Fredrik ^a   Samuelsson, Lena ^a   Torinsson, Åsa ^a   Wahlström, Jan ^a   Swanbeck, Gunnar ^a   Martinsson, Tommy ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cytogenetics; FISH; Psoriasis; Translocation

Indexed keywords

HLA ANTIGEN;

ARTICLE; ATOPY; CHROMOSOME 11Q; CHROMOSOME 6; CHROMOSOME TRANSLOCATION 11; CYTOGENETICS; FLUORESCENCE IN SITU HYBRIDIZATION; GENOME; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PSORIASIS; TELOMERE;

EID: 17144459708     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200311     Document Type: Article

References (24)

1. Swanbeck G, Inerot A, Martinsson T, Wahlström J: A population genetic study of psoriasis. Br J Dermatol 1994; 131: 32-39.
2. Trembath RC, Clough RL, Rosbotham JL et al: Identification of a major susceptibility locus on chromosome 6p and evidence for further disease loci revealed by a two stage genome-wide search in psoriasis. Hum Mol Genet 1997; 6: 813-820.
3. Tomfohrde J, Silverman A, Barnes R et al: Gene for familiar psoriasis susceptibility mapped to the distal end of human chromosome 17q. Science 1994; 264: 1141-1145.
4. Matthews D, Fry L, Powles A et al: Evidence that a locus for familial psoriasis maps to chromosome 4q. Nat Genet 1996; 14: 231-233.
5. Nair RP, Henseler T, Jenisch S et al: Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. Hum Mol Genet 1997; 8: 1349-1356.
6. Enlund F, Samuelsson L, Enerbäck C et al: Analysis of three suggested psoriasis susceptibility loci in a large Swedish material; confirmation of linkage to chromosome 6p(HLA-region), and to 17q, but not to 4q. Hum Hered (in press).
7. Greenstein RM, Reardon MP, Chan TS: An X-autosome translocation in a girl with Duchenne Muscular Dystrophy (DMD): evidence for DMD gene localization. Pediatr Res 1977; 11: 457.
8. Fountain JW, Wallace MR, Brereton AM et al: Physical mapping of the von Recklinghausen neurofibromatosis region on chromosome 17. Am J Genet 1989; 44: 58-67.
9. Swanbeck G, Inerot A, Martinsson T et al: Genetic councelling in psoriasis. Br J Dermatol 1997; 137: 939-942.
10. Johannesson T, Holmqvist D, Martinsson T, Wahlström J: An improved technique for chromosome preparations from human lymphocytes. Hereditas 1991; 115: 295-297.
11. Dib C, Faure C, Samson N, Drouot A et al: A comprehensive genetic map of the human genome based on 5,264 microsatellites. Nature 1996; 380: 152-154.
12. Petronzelli F, Bonamico M, Ferrante P et al: Genetic contribution of the HLA region to the familial clustering of coeliac disease. Ann Hum Genet 1997; 61: 307-317.
13. Greco L, Corazza G, Babron MC et al: Genome search in celiac disease. Am J Genet 1998; 62: 669-675.
14. Michaelsson G, Gerdén B: How common is gluten intolerance among patients with psoriasis? Acta Derm Ven 1991; 71: 90.
15. Hashimoto L, Habita C, Beressi JP et al: Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11q. Nature 1994; 371: 8.
16. Cookson WOCM, Sharp P, Faux JA, Hopkin JM: Linkage between immunoglobulin E responses underlaying asthma and rhinitis and chromosome 11q. Lancet 1989; I: 1292-1295.
17. Sandford AJ, Shirakawa T, Moffatt MF et al: Localisation of atopy and beta subunit of high-affinity IgE receptor (FCER1) on chromosome 11q. Lancet 1993; 341: 332-334.
18. Risch SS, Roitman-Johnson B, Greenberg et al: Genetic analysis of atopy in three large kindreds: no evidence of linkage to D11S97. Clin Exp Allergy 1992; 22: 1070-1076.
19. Wallace C, Bernstein R, Pinto MR: Non-random in vitro 7;14 translocations detected in a routine cytogenetic series. Hum Genet 1984; 66: 157-161.
20. Satsangi J, Parker M, Louis M et al: Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosome 3, 7 and 12. Nat Genet 1996; 14: 199-202.
21. Becker KG, Simon R, Bailey-Wilson JE et al: Clustering of non-major histocompatibility complex loci in human autoimmune diseases. Proc Natl Acad Sci USA 1998; 95: 9979-9984.
22. Nielsen J, Zachariae H: Chromosome aberrations in severe psoriasis. Acta Derm Ven 1973; 53: 192-194.
23. Locher H, Fränz J: Chromosomenveränderungen bei Methotrexatebehandlungen. Med Welt 1967; 34: 1956.
24. Jacobs PA, Melville M, Ratcliffe S: A cytogenetic survey of 11,680 newborn infants. Ann Hum Genet 1974; 37: 359.