TrkA receptors delay C6-2B glioma cell growth in rat striatum

Molecular Brain Research

Volumn 56, Issue 1-2, 1998, Pages 273-276

  Rabin, Stuart J ^a   Tornatore, Carlo ^b   Baker Cairns, Belinda ^c   Spiga, Giulio ^a   Mocchetti, Italo ^a  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Glioblastoma multiforme; NGF; P75NTR; TrkA

Indexed keywords

NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN TUMOR; CELL GROWTH; CELL TRANSPLANTATION; CONTROLLED STUDY; CORPUS STRIATUM; DOWN REGULATION; GLIOBLASTOMA; GLIOMA CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PRIORITY JOURNAL; RAT; TUMOR; TUMOR GROWTH;

ANIMALS; CELL DIVISION; CORPUS STRIATUM; GLIOMA; IMMUNOHISTOCHEMISTRY; PROTO-ONCOGENE PROTEINS; RATS; RATS, NUDE; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 17144441105     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(98)00020-5     Document Type: Article

References (18)

1. Burger P.C., Green S.B. Patient age, histological features, and length of survival in patients with glioblastoma multiforme. Cancer. 59:1987;1617-1625.
2. Chao M., Hempstead B. p75 and Trk: a two-receptor system. Trends Neurosci. 18:1995;321-326.
3. Clary D.O., Weskamp G., Austin L.A., Reichardt L.F. TrkA cross-linking mimics neuronal responses to nerve growth factor. Mol. Biol. Cell. 5:1994;549-563.
4. Colangelo A.M., Fink D.W., Rabin S.J., Mocchetti I. Induction of nerve growth factor responsiveness in C6-2B glioma cells by expression of TrkA proto-oncogene. Glia. 12:1994;117-127.
5. Conrad C.A., Milosavlijevic V.P., Yung A.W.K. Advances in chemotherapy for brain tumors. Neurol. Clin. 13:1995;795-812.
6. Kaplan D.R., Hempstead B.L., Martin-Zanca D., Chao M.V., Parada L.F. The trk protooncogene product: A signal transducing receptor for nerve growth factor. Science. 252:1991;554-558.
7. Lachyankar M.B., Ross A.H., Litofsky S., Condor P.J., Quesenberry P.J., Recht L.D. TrkA expression decreases the in vivo aggressiveness of C6 glioma cells. Cancer Res. 57:1997;532-536.
8. Levi-Montalcini R. The nerve growth factor 35 years later. Science. 237:1987;1154-1162.
9. Matsushima H., Bogenmann E. Expression of TrkA cDNA in neuroblastomas mediates differentiation in vitro and in vivo. Mol. Cell. Biol. 13:1993;7447-7456.
10. Missale C., Boroni F., Losa M., Giovannelli M., Zannellato A., Dal Toso R., Balsani A., Spano P.F. Nerve growth factor suppresses the transforming phenotype of human prolactinomas. Proc. Natl. Acad. Sci. U.S.A. 90:1993;7961-7965.
11. Mocchetti I., De Bernardi M.A., Szekely A.M., Alho H., Brooker G., Costa E. Regulation of NGF biosynthesis by beta-adrenergic receptor activation in astrocytoma cells: A potential role of c-Fos protein. Proc. Natl. Acad. Sci. U.S.A. 86:1989;3891-3895.
12. Mocchetti I., Spiga G., Hayes V.Y., Isackson P.J., Colangelo A.M. Glucocorticoids differentially increase nerve growth factor and basic fibroblast growth factor expression in the rat brain. J. Neurosci. 16:1996;2141-2148.
13. Muragaki Y., Chou T.T., Kaplan D.R., Trojanowski J.Q., Lee V.M.-Y. Nerve growth factor induces apoptosis in human medulloblastoma cell line that express TrkA receptors. J. Neurosci. 17:1997;530-542.
14. Palmer T.D., Rosman G.J., Osborne W.R., Miller A.D. Genetically modified skin fibroblasts persist long term after transplantation but gradually inactivate introduced genes. Proc. Natl. Acad. Sci. U.S.A. 88:1991;1330-1334.
15. Poluha W., Poluha D.K., Ross A.H. TrkA neurogenic receptor regulates differentiation of neuroblastoma cells. Oncogene. 10:1995;185-189.
16. Rabin S.J., Tornatore C., Baker-Cairns B., Keir S., Mocchetti I. TrkA expression attenuates C6 glioma cell growth: in vivo and in vitro studies. Neurosci. abstr. 487.8:1996.
17. Shrieve D.C., Loeffler J.S. Advances in radiation therapy for brain tumors. Neurol. Clin. 13:1995;773-793.
18. Tornatore C., Rabin S.J., Baker-Cairns B., Keir S., Mocchetti I. Engraftment of C6-2B cells into the striatum of ACI nude rats as a tool for comparison of the in vitro and in vivo phenotype of a glioma cell line. Cell Transplant. 6:1997;317-326.