Synthesis of a series of sulfinic acid analogs of GABA and evaluation of their GABA(B) receptor affinities

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 21, 1998, Pages 3059-3064

  Carruthers, Nicholas I ^a   Spitler, James M ^a   Wong, Shing Chun ^a   Blythin, David J ^a   Chen, Xiao ^a   Shue, Ho Jane ^a   She, Hoyan S ^a   Lee, Joe F ^a   Rizzo, Charles ^a   Ting, Pauline C ^a   West Jr , Robert E ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; BACLOFEN; SULFINIC ACID DERIVATIVE;

ARTICLE; CENTRAL NERVOUS SYSTEM; DRUG EFFECT; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; EPOXIDATION; FOURIER TRANSFORMATION; NEUROTRANSMITTER RELEASE; NONHUMAN; PEPTIDE SYNTHESIS; RECEPTOR AFFINITY; STOMACH ACID SECRETION;

GAMMA-AMINOBUTYRIC ACID; RECEPTORS, GABA-B; STRUCTURE-ACTIVITY RELATIONSHIP; SULFINIC ACIDS;

EID: 17144439227     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00565-4     Document Type: Article

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