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Volumn 272, Issue 1 35-1, 1997, Pages

Measurement of hepatic R(a) UDP-glucose in vivo in rats: Relation to glycogen deposition and labeling patterns

Author keywords

galactose; glycogen synthesis; hepatic metabolism; in vivo metabolism; intracellular fluxes; noninvasive probes

Indexed keywords

GALACTOSE; GLUCURONIC ACID; GLYCOGEN; URIDINE DIPHOSPHATE GLUCOSE; CARBON; GLUCOSE; GLYCEROL;

EID: 17144435393     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.1997.272.1.e155     Document Type: Article
Times cited : (22)

References (30)
  • 3
    • 1842311393 scopus 로고
    • In vivo measurement of the appearance rate of hepatic UDP-glucose and partitioning of gluconeogenic flux in fasting and refed rat
    • Hellerstein, M. K. In vivo measurement of the appearance rate of hepatic UDP-glucose and partitioning of gluconeogenic flux in fasting and refed rat (Abstract). Clin. Res. 35: 505A, 1987.
    • (1987) Clin. Res. , vol.35
    • Hellerstein, M.K.1
  • 4
    • 0027954268 scopus 로고
    • Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers
    • Hellerstein, M. K., N. L. Benowitz, R. A. Neese, R. Hoh, P. Jacob, I. Fong, J. Hsieh, and D. Faix. Effects of cigarette smoking and its cessation on lipid metabolism and energy expenditure in heavy smokers. J. Clin. Invest. 93: 265-272, 1994.
    • (1994) J. Clin. Invest. , vol.93 , pp. 265-272
    • Hellerstein, M.K.1    Benowitz, N.L.2    Neese, R.A.3    Hoh, R.4    Jacob, P.5    Fong, I.6    Hsieh, J.7    Faix, D.8
  • 6
    • 0022525686 scopus 로고
    • Glycoconjugates as non-invasive probes of intrahepatic metabolism: Pathways of glucose entry into compartmentalized hepatic UDP-glucose pools during glycogen accumulation
    • Hellerstein, M. K., D. J. Greenblatt, and H. N. Munro. Glycoconjugates as non-invasive probes of intrahepatic metabolism: pathways of glucose entry into compartmentalized hepatic UDP-glucose pools during glycogen accumulation. Proc. Natl. Acad. Sci. USA 83: 7044-7048, 1986.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 7044-7048
    • Hellerstein, M.K.1    Greenblatt, D.J.2    Munro, H.N.3
  • 7
    • 0028926483 scopus 로고
    • Rate of glucose entry into hepatic UDP-glucose by the direct pathway in fasted and fed states in normal humans
    • Hellerstein, M. K., S. Kaempfer, J.-M. Schwarz, K. Wu, and C. H. L. Shackleton. Rate of glucose entry into hepatic UDP-glucose by the direct pathway in fasted and fed states in normal humans. Metab. Clin. Exp. 44: 172-182, 1995.
    • (1995) Metab. Clin. Exp. , vol.44 , pp. 172-182
    • Hellerstein, M.K.1    Kaempfer, S.2    Schwarz, J.-M.3    Wu, K.4    Shackleton, C.H.L.5
  • 8
    • 0026448766 scopus 로고
    • Mass isotopomer distribution analysis: A technique for measuring biosynthesis and turnover of polymers
    • Endocrinol. Metab. 26
    • Hellerstein, M. K., and R. A. Neese. Mass isotopomer distribution analysis: a technique for measuring biosynthesis and turnover of polymers. Am. J. Physiol. 263 (Endocrinol. Metab. 26): E988-E1001, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Hellerstein, M.K.1    Neese, R.A.2
  • 9
    • 0031014206 scopus 로고    scopus 로고
    • Altered fluxes responsible for reduced hepatic glucose production and gluconeogenesis by exogenous glucose in rats
    • Endocrinol. Metab. 35
    • Hellerstein, M. K., R. A. Neese, J.-M. Schwarz, S. Turner, D. Faix, and K. Wu. Altered fluxes responsible for reduced hepatic glucose production and gluconeogenesis by exogenous glucose in rats. Am. J. Physiol. 272 (Endocrinol. Metab. 35): E163-E172, 1997.
    • (1997) Am. J. Physiol. , vol.272
    • Hellerstein, M.K.1    Neese, R.A.2    Schwarz, J.-M.3    Turner, S.4    Faix, D.5    Wu, K.6
  • 10
    • 0025859708 scopus 로고
    • Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution
    • Hellerstein, M. K., K. Wu, S. Kaempfer, C. Kletke, and C. H. L. Shackleton. Sampling the lipogenic hepatic acetyl-CoA pool in vivo in the rat. Comparison of xenobiotic probe to values predicted from isotopomeric distribution in circulating lipids and measurement of lipogenesis and acetyl-CoA dilution. J. Biol. Chem. 266: 10912-10919, 1991.
    • (1991) J. Biol. Chem. , vol.266 , pp. 10912-10919
    • Hellerstein, M.K.1    Wu, K.2    Kaempfer, S.3    Kletke, C.4    Shackleton, C.H.L.5
  • 11
    • 0025214987 scopus 로고
    • The relationship between gluconeogenic substrate supply and glucose production in humans
    • Endocrinol. Metab. 21
    • Jahoor, F., E. J. Peters, and R. R. Wolfe. The relationship between gluconeogenic substrate supply and glucose production in humans. Am. J. Physiol. 258 (Endocrinol. Metab. 21): E288-E296, 1990.
    • (1990) Am. J. Physiol. , vol.258
    • Jahoor, F.1    Peters, E.J.2    Wolfe, R.R.3
  • 12
    • 0025079179 scopus 로고
    • Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans: Demonstration of hepatic autoregulation without a change in plasma glucose concentration
    • Jenssen, T., N. Nurjhan, A. Consoli, and J. E. Gerich. Failure of substrate-induced gluconeogenesis to increase overall glucose appearance in normal humans: demonstration of hepatic autoregulation without a change in plasma glucose concentration. J. Clin. Invest. 86: 489-497, 1990.
    • (1990) J. Clin. Invest. , vol.86 , pp. 489-497
    • Jenssen, T.1    Nurjhan, N.2    Consoli, A.3    Gerich, J.E.4
  • 13
    • 0016873527 scopus 로고
    • Futile cycles in the metabolism of glucose
    • edited by B. Horecker and E. Stadman. New York: Academic
    • Katz, J., and R. Rognstad. Futile cycles in the metabolism of glucose. In: Current Topics in Cellular Regulation, edited by B. Horecker and E. Stadman. New York: Academic, 1976, vol. 10, p. 238-239.
    • (1976) Current Topics in Cellular Regulation , vol.10 , pp. 238-239
    • Katz, J.1    Rognstad, R.2
  • 14
    • 0022977654 scopus 로고
    • Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects
    • Klein, S., V. R. Young, G. L. A. Blackburn, B. R. Bistrian, and R. R. Wolfe. Palmitate and glycerol kinetics during brief starvation in normal weight young adult and elderly subjects. J. Clin. Invest. 78: 928-933, 1986.
    • (1986) J. Clin. Invest. , vol.78 , pp. 928-933
    • Klein, S.1    Young, V.R.2    Blackburn, G.L.A.3    Bistrian, B.R.4    Wolfe, R.R.5
  • 15
    • 3242858033 scopus 로고
    • Comparison of precursor pool enrichments (p) and fractional gluconeogenesis (f) for secreted glucuronate (GIcUA) and plasma glucose (Glc)
    • Letscher, A. E., R. A. Neese, S. Turner, J.-M. Schwarz, D. Cesar, and M. K. Hellerstein. Comparison of precursor pool enrichments (p) and fractional gluconeogenesis (f) for secreted glucuronate (GIcUA) and plasma glucose (Glc) (Abstract). FASEB J. 8: A954, 1994.
    • (1994) FASEB J. , vol.8
    • Letscher, A.E.1    Neese, R.A.2    Turner, S.3    Schwarz, J.-M.4    Cesar, D.5    Hellerstein, M.K.6
  • 17
    • 0003117264 scopus 로고
    • D-Glucaric acid
    • edited by R. L. Whistler, M. L. Wolfrom, and J. N. Bomiller. New York: Academic
    • Mehltretter, C. L. D-Glucaric acid. In: Methods in Carbohydrate Chemistry, edited by R. L. Whistler, M. L. Wolfrom, and J. N. Bomiller. New York: Academic, 1963, p. 46-48.
    • (1963) Methods in Carbohydrate Chemistry , pp. 46-48
    • Mehltretter, C.L.1
  • 18
    • 0001580155 scopus 로고
    • Evolution of protein metabolism in mammals
    • edited by H. N. Munro. New York: Academic
    • Munro, H. N. Evolution of protein metabolism in mammals. In: Mammalian Protein Metabolism, edited by H. N. Munro. New York: Academic, 1969, vol. III, p. 133-182.
    • (1969) Mammalian Protein Metabolism , vol.3 , pp. 133-182
    • Munro, H.N.1
  • 19
    • 0028980981 scopus 로고
    • Measurement of gluconeogenesis and rate of appearance of intrahepatic triose-phosphate and its regulation by substrates by mass isotopomer distribution analysis (MIDA). Testing of assumptions and potential problems
    • Neese, R. A., D. Faix, J.-M. Schwarz, S. M. Turner, D. Vu, and M. K. Hellerstein. Measurement of gluconeogenesis and rate of appearance of intrahepatic triose-phosphate and its regulation by substrates by mass isotopomer distribution analysis (MIDA). Testing of assumptions and potential problems. J. Biol. Chem. 270: 14452-14463, 1995.
    • (1995) J. Biol. Chem. , vol.270 , pp. 14452-14463
    • Neese, R.A.1    Faix, D.2    Schwarz, J.-M.3    Turner, S.M.4    Vu, D.5    Hellerstein, M.K.6
  • 20
    • 0021333207 scopus 로고
    • Evidence for suppression of hepatic glucose-6-phosphatase with carbohydrate feeding
    • Newgard, C. B., D. W. Foster, and J. D. McGarry. Evidence for suppression of hepatic glucose-6-phosphatase with carbohydrate feeding. Diabetes 33: 192-195, 1984.
    • (1984) Diabetes , vol.33 , pp. 192-195
    • Newgard, C.B.1    Foster, D.W.2    McGarry, J.D.3
  • 21
    • 0015712086 scopus 로고
    • Liver glycogen in man - The effect of total starvation or a carbohydrate-poor diet followed by carbohydrate refeeding
    • Nilsson, L. H., and E. Hultman. Liver glycogen in man - the effect of total starvation or a carbohydrate-poor diet followed by carbohydrate refeeding. Scand. J. Lab. Invest. 32: 325-330, 1973.
    • (1973) Scand. J. Lab. Invest. , vol.32 , pp. 325-330
    • Nilsson, L.H.1    Hultman, E.2
  • 22
    • 0025994801 scopus 로고
    • No reduction in total hepatic glucose output by inhibition of gluconeogenesis with ethanol in NIDDM patients
    • Puhakeinen, I., V. A. Koivisto, and H. Yki-Jarvinen. No reduction in total hepatic glucose output by inhibition of gluconeogenesis with ethanol in NIDDM patients. Diabetes 40: 1319-1327, 1991.
    • (1991) Diabetes , vol.40 , pp. 1319-1327
    • Puhakeinen, I.1    Koivisto, V.A.2    Yki-Jarvinen, H.3
  • 23
    • 0025078498 scopus 로고
    • Liquid chromatography/mass spectrometry of plasma glucose and secreted glucuronate for metabolic studies in humans
    • Reid, J. S., S. Kaempfer, K. Wu, M. K. Hellerstein, and C. H. L. Shackleton. Liquid chromatography/mass spectrometry of plasma glucose and secreted glucuronate for metabolic studies in humans. Biomed. Mass. Spectrom. 19: 535-540, 1990.
    • (1990) Biomed. Mass. Spectrom. , vol.19 , pp. 535-540
    • Reid, J.S.1    Kaempfer, S.2    Wu, K.3    Hellerstein, M.K.4    Shackleton, C.H.L.5
  • 24
    • 0027199061 scopus 로고
    • Mechanism by which hyperglycemia inhibits glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes
    • Rossetti, L., A. Giaccari, N. Barzilai, K. Howard, G. Sebel, and M. Hu. Mechanism by which hyperglycemia inhibits glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes. J. Clin. Invest. 92: 1126-1134, 1993.
    • (1993) J. Clin. Invest. , vol.92 , pp. 1126-1134
    • Rossetti, L.1    Giaccari, A.2    Barzilai, N.3    Howard, K.4    Sebel, G.5    Hu, M.6
  • 25
    • 0028849608 scopus 로고
    • Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting
    • Endocrinol. Metab. 32
    • Rother, K. I., and W. F. Schwenk. Hepatic glycogen accurately reflected by acetaminophen glucuronide in dogs refed after fasting. Am. J. Physiol. 269 (Endocrinol. Metab. 32): E766-E773, 1995.
    • (1995) Am. J. Physiol. , vol.269
    • Rother, K.I.1    Schwenk, W.F.2
  • 26
    • 13144286656 scopus 로고
    • Acetaminophen glucuronidation accurately reflects gluconeogenesis in fasted dogs
    • Schwenk, M. F. Acetaminophen glucuronidation accurately reflects gluconeogenesis in fasted dogs. Clin. Res. 38: 309A, 1990.
    • (1990) Clin. Res. , vol.38
    • Schwenk, M.F.1
  • 27
    • 0007562377 scopus 로고
    • Disorders of galactose metabolism
    • edited by J. B. Stanbury, J. B. Wyngaarden, and D. S. Fredrickson. New York: McGraw-Hill
    • Segal, S. Disorders of galactose metabolism. In: The Metabolic Basis of Inherited Disease (5th ed.), edited by J. B. Stanbury, J. B. Wyngaarden, and D. S. Fredrickson. New York: McGraw-Hill, 1983, p. 167-191.
    • (1983) The Metabolic Basis of Inherited Disease (5th Ed.) , pp. 167-191
    • Segal, S.1
  • 28
    • 0010629572 scopus 로고
    • Some observations in the metabolism of D-galactose in normal man
    • Segal, S., and A. Blair. Some observations in the metabolism of D-galactose in normal man. J. Clin. Invest. 40: 2016-2025, 1961.
    • (1961) J. Clin. Invest. , vol.40 , pp. 2016-2025
    • Segal, S.1    Blair, A.2
  • 29
    • 0347366555 scopus 로고
    • Glucose load diverts hepatic gluconeogenic product from glucose to glycogen in vivo
    • Endocrinol. Metab. Gastrointest. Physiol. 4
    • Shikama, H., and M. Ui. Glucose load diverts hepatic gluconeogenic product from glucose to glycogen in vivo. Am. J. Physiol. 235 (Endocrinol. Metab. Gastrointest. Physiol. 4): E354-E360, 1978.
    • (1978) Am. J. Physiol. , vol.235
    • Shikama, H.1    Ui, M.2
  • 30
    • 0023664910 scopus 로고
    • Fructose effect to suppress hepatic glycogen degradation
    • Youn, J. H., H. R. Kaslow, and R. N. Bergman. Fructose effect to suppress hepatic glycogen degradation. J. Biol. Chem. 262: 11470-11477, 1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 11470-11477
    • Youn, J.H.1    Kaslow, H.R.2    Bergman, R.N.3


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