Hematopoietic capacity of adult human skeletal muscle is negligible

Bone Marrow Transplantation

Volumn 35, Issue 7, 2005, Pages 663-666

  Allan, D S ^a,b   Jay, K E ^a   Bhatia, M ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Muscle; Stem cells; Transplantation

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; ERYTHROPOIETIN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; COLONY FORMING UNIT; CONTROLLED STUDY; EX VIVO STUDY; FETUS; FLOW CYTOMETRY; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; SCID MOUSE; SKELETAL MUSCLE;

ADULT; ANIMALS; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELLS, CULTURED; GRAFT SURVIVAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; MICE; MICE, SCID; MUSCLE, SKELETAL; TRANSPLANTATION, HETEROLOGOUS;

EID: 17144427015     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704866     Document Type: Article

References (14)

1. Jackson KA, Mi T, Goodell MA. Hematopoietic potential of stem cells isolated from murine skeletal muscle. Proc Natl Acad Sci USA 1999; 96: 14482-14486.
2. McKinney-Freeman SL, Jackson KA, Camargo FD et al. Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci USA 2002; 99: 1341-1346.
3. Kawada H, Ogawa M. Bone marrow origin of hematopoietic progenitors and stem cells in murine muscle. Blood 2001; 98: 2008-2013.
4. Geiger H, True JM, Grimes B et al. Analysis of the hematopoietic potential of muscle-derived cells in mice. Blood 2002; 100: 721-723.
5. Issarachai S, Priestley GV, Nakamoto B, Papayannopoulou T. Cells with hemopoietic potential residing in muscle are itinerant bone marrow-derived cells. Exp Hematol 2002; 30: 366-373.
6. Majka SM, Jackson KA, Kienstra KA et al. Distinct progenitor populations in skeletal muscle are bone-marrow derived and exhibit different cell fates during vascular regeneration. J Clin Invest 2003; 111: 71-79.
7. Jay KE, Gallacher L, Bhatia M. Emergence of muscle and neural hematopoiesis in humans. Blood 2002; 100: 3193-3202.
8. Dell'Agnola C, Rabascio C, Mancuso P et al. In vitro and in vivo hematopoietic potential of human stem cells residing in muscle tissue. Exp Hematol 2002; 30: 905-914.
9. Maeno M, Mead PE, Kelley C et al. The role of BMP-4 and GATA-2 in the induction and differentiation of hematopoietic mesoderm in Xenopus laevis. Blood 1996; 88: 1965-1972.
10. Kelley C, Yee K, Harland R, Zon LI. Ventral expression of GATA-1 and GATA-2 in the Xenopus embryo defines induction of hematopoietic mesoderm. Dev Biol 1994; 165: 193 205.
11. 1-negative progenitors in treated as well as newly diagnosed patients. Blood 1984; 63: 1172-1177.
12. Eaves CJ, Eaves AC. Erythroid progenitor cell numbers in human marrow - implication for regulation. Exp Hematol 1979; 7 (Suppl. 5): 54.
13. Lillioja S, Young AA, Culter CL et al. Skeletal muscle capillary density and fiber type are possible determinants of in vivo insulin resistance in man. J Clin Invest 1987; 80: 415-424.
14. McGuire BJ, Secomb TW. A theoretical model for oxygen transport in skeletal muscle under conditions of high oxygen demand. J Appl Physiol 2001; 91: 2255-2265.