Evaluation of a rapid bedside toxicology screen in patients suspected of drug toxicity

Journal of Emergency Medicine

Volumn 28, Issue 4, 2005, Pages 389-394

  Tomaszewski, Christian ^a   Runge, Jeffrey ^a   Gibbs, Michael ^a   Colucciello, Stephen ^a   Price, Marlow ^a  

^a CAROLINAS MEDICAL CENTER   (United States)

Author keywords

drug screens; emergency department; point of care testing; toxicology

Indexed keywords

AMPHETAMINE; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; CARBAMAZEPINE; COCAINE; DIBENZAZEPINE; ILLICIT DRUG; OPIATE; PHENCYCLIDINE; TETRAHYDROCANNABINOL; TRICYCLIC ANTIDEPRESSANT AGENT; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC KIT; DRUG ABUSE; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IMMUNOASSAY; INFANT; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCREENING TEST; TANDEM MASS SPECTROMETRY; TOXICITY TESTING;

EID: 17144404841     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jemermed.2004.11.021     Document Type: Article

References (22)

1. J.D. Mahoney, P.L. Gross, T.A. Stern Quantitative serum toxic screening in the management of suspected drug overdose Am J Emerg Med 8 1990 16 22
2. A.S. Brett Implications of discordance between clinical impression and toxicology analysis in drug overdose Arch Intern Med 148 1998 437 441
3. A.L. Kellerman, S.D. Fihn, J.P. LoGerfo Impact of drug screeening in suspected overdose Ann Emerg Med 16 1987 1206 1216
4. A.H.B. Wu, S.S. Wong, K.G. Johnson Evaluation of the Triage system for emergency drugs-of-abuse testing in urine J Anal Toxicol 17 1993 241 245
5. K.F. Buechler, S. Moi, B. Noar Simultaneous detection of seven drugs of abuse by the Triage panel for drugs of abuse Clin Chem 38 1992 1678 1684
6. J.G. Schwartz, I.L. Hurd, J.J. Carnahan Determination of tricyclic antidepressants for ED analysis Am J Emerg Med 12 1994 513 516
7. Technical Bulletin Triage™ Plus TCA. Panel for drugs of abuse plus tricyclic antidepressants 1994 Biosite Diagnostics San Diego, CA
8. B. Dawson-Saunders, R.G. Trapp Basic and clinical biostatistics 2 edn. 1994 Appleton & Lange Norwalk, CT 143 161
9. S.R. Biggs, L.F. Chasseaud, D.R. Hawkins Determination of amitriptyline and its major basic metabolites in human urine by high-performance liquid chromatography Drug Metab Dispos 7 1979 233 236
10. J.L. Valentine, E.M. Komoroski Use of a visual panel detection method for drugs of abuse clinical and laboratory experience with children and adolescents J Pediatr 126 1995 135 140
11. R. de la Torre, A. Domingo-Salvany, R. Badia Clinical evaluation of the Triage™ analytical device for drugs-of-abuse testing Clin Chem 42 1996 1433 1438
12. S.D. Ferrara, L. Tedeschi, G. Frison Drugs-of-abuse testing in urine statistical approach and experimental comparison of immunochemical and chromatographic techniques J Anal Toxicol 18 1994 278 291
13. R.L. Fitzgerald, D.A. Rexin, D.A. Herold Detecting benzodiazepines immunoassays compared with negative chemical ionization gas chromatography/mass spectrophotometry Clin Chem 40 1994 373 380
14. T.R. Koch, R.L. Raglin, S. Kirk Improved screening for benzodiazepine metaboites in urine using the Triage™ Panel for Drugs of Abuse J Anal Toxicol 18 1994 168 172
15. P.T. Mearrick, J.S. Chahl Screening for benzodiazepines in urine after hydrolysis of glucuronide conjugates Clin Chem 31 1985 152
16. O. Beck, P. Lafolie, G. Odelius Immunological screening of benzodiazepines in urine improved detection of oxazepam intake Toxicol Lett 52 1990 7 14
17. O. Beck, P. Lafolie, P. Hjemdahl Detection of benzodiazepine intake in therapeutic doses by immunoanalysis of urine two techniques evaluated and modified for improved performance Clin Chem 38 1992 271 275
18. A.D. Fraser, R. Meatherall Comparative evaluation of five immunoassays for the analysis of alprazolam and triazolam metabolites in urine effect of lowering the screening and GC-MS cut-off values J Anal Toxicol 20 1996 217 223
19. thedn. 1996 McGraw-Hill New York, NY
20. A.S. Christophersen Tetrahydrocannibinol stability in whole blood plastic versus glass containers J Anal Toxicol 10 1992 129 131
21. S.M. Furst, P. Sukhai, R.A. McClelland Covalent binding of carbamazepine oxidative metabolites to neutrophils Drug Metab Dispos 23 1995 590 594
22. J.M. Sugarman, G.C. Rodgers, R.I. Paul Utility of toxicology screening in a pediatric emergency department Pediatr Emerg Care 13 1997 194 197