The metalation of 1- and 2-(trifluoromethyl)naphthalenes: Noteworthy site selectivities

Synthesis

Volumn , Issue 5, 2005, Pages 798-803

  Cottet, Fabrice ^a   Castagnetti, Eva ^a   Schlosser, Manfred ^a  

^a EPFL   (Switzerland)

Author keywords

(trifluoromethyl)naphthalenes; (trifluoromethyl)napnthoic acids; Metal coordination; Metalations; Regioselectivity; Superbases

Indexed keywords

ACIDITY; CARBON DIOXIDE; ELECTRON TRANSITIONS; ISOMERS; LITHIUM COMPOUNDS; ORGANOMETALLICS; POTASSIUM COMPOUNDS; REACTION KINETICS;

1- AND 2-(TRIFULOROMETHYL)NAPHTHALENES; ELECTRONEGATIVE SUBSTITUENTS EFFECTS; KINETIC ACIDITY; METALATION;

NAPHTHALENE;

1 (TRIFLUOROMETHYL)NAPHTHALENE DERIVATIVE; 1 TRIFLUOROMETHYL 2 NAPHTHOIC ACID; 2 (TRIFLUOROMETHYL)NAPHTHALENE DERIVATIVE; 2 TRIFLUOROMETHYL 1 NAPHTHOIC ACID; 3 TRIFLUOROMETHYL 1 NAPHTHOIC ACID; 3 TRIFLUOROMETHYL 2 NAPHTHOIC ACID; CARBON DIOXIDE; ETHYLENEDIAMINE DERIVATIVE; LITHIUM DERIVATIVE; N,N,N',N' TETRAMETHYLETHYLENEDIAMINE; ORGANOMETALLIC COMPOUND; TERT BUTYLLITHIUM; UNCLASSIFIED DRUG;

ACIDITY; ARTICLE; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; ELECTROCHEMICAL ANALYSIS; ELECTRON TRANSPORT; ISOMERISM; METALLATION; STEREOCHEMISTRY;

EID: 17144394435     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-861814     Document Type: Article

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